GO:0043066 | negative regulation of apoptosis |
GO:0043154 | negative regulation of caspase activity |
GO:0043085 | positive regulation of catalytic activity |
CASP8 and FADD-like apoptosis regulator |
詳細情報を見る |
同義遺伝子名
I-FLICE, Flip, Cash, CASH, c-Flip, Caspase homolog, FADD-like antiapoptotic molecule 1, MACH-related inducer of toxicity, Casper, Cellular FLICE-like inhibitory protein, Usurpin, MGC103395, CLARP, Caspase-like apoptosis regulatory protein, Caspase-eight-related protein, CASP8 and FADD-like apoptosis regulator, Cflar, CASP8 and FADD-like apoptosis regulator precursor, c-FLIP, MRIT, Inhibitor of FLICE, FLAME, FLAME-1
Refseq ID | NM_207653 |
---|---|
Gene ID | 12633 |
Unigene ID | Mm.336848 |
Probe set ID | 1425686_at [Mouse430_2] |
Ensembl ID | ENSMUSG00000026031 |
ヒト[18] | NM_001127183, NM_001127184, NM_001202515, NM_001202516, NM_001202517, NM_001202518, NM_001202519, NM_003879 |
ラット[2] | NM_001033864, NM_057138, NM_001202515, NM_001202516, NM_001202517, NM_001202518, NM_001202519, NM_003879 |
- |
IPR001875 | Death effector |
IPR011029 | DEATH-like |
IPR011600 | Peptidase C14, caspase catalytic |
IPR015917 | Peptidase C14, caspase precursor p45, core |
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Biological Process
Cellular Component
GO:0031265 | CD95 death-inducing signaling complex |
GO:0005737 | cytoplasm |
GO:0031264 | death-inducing signaling complex |