corticotropin releasing hormone receptor 1

詳細情報を見る

同義遺伝子名

CRF1, CRF 1 receptor, Corticotropin-releasing hormone receptor 1, MGC124240, CRFR1, MGC124237, CRF-R, CRF-R1alpha, Crhr1, corticotropin releasing hormone receptor 1, CRH-R 1, Crhr

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:6.87 小脳:9.27 脳幹:- 脳梁:- 松果体:- 末梢神経:5.86 脊柱:6.75 網膜:6.03 目:6.15 動脈:- 静脈:5.61 リンパ節:5.55 末梢血:- 脾臓:5.92 胸腺:- 骨髄:5.71 脂肪:5.65 骨:5.63 皮膚:5.54
CAGE 大脳:2.30 小脳:- 脳幹:1.49 脳梁:- 松果体:- 末梢神経:- 脊柱:0.91 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0.62 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0.15
RNA-seq 大脳:5.85 小脳:5.85 脳幹:5.85 脳梁:5.85 松果体:5.85 末梢神経:5.85 脊柱:5.85 網膜:5.85 目:5.85 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:9.40 乳腺:- 唾液腺:-
GeneChip 子宮:5.55 胎盤:5.57 前立腺:5.70 卵巣:5.46 精巣:5.98 心臓:6.14 骨格筋:5.91 食道:- 胃:5.70 腸:5.47 結腸:- 肝臓:6.01 肺:5.47 膀胱:5.62 腎臓:5.73 下垂体:6.87 甲状腺:- 副腎:5.29 膵臓:6.37 乳腺:5.56 唾液腺:5.90
CAGE 子宮:0 胎盤:0 前立腺:0.37 卵巣:0.13 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:0 膀胱:0 腎臓:- 下垂体:2.01 甲状腺:- 副腎:0 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007762
Gene ID 12921
Unigene ID Mm.189201
Probe set ID 1418810_at  [Mouse430_2]
Ensembl ID ENSMUSG00000018634

オーソログ対応遺伝子

ヒト[12]  NM_001145146, NM_001145147, NM_001145148, NM_004382
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0048148  behavioral response to cocaine
GO:0048149  behavioral response to ethanol
GO:0048266  behavioral response to pain
GO:0007166  cell surface receptor linked signal transduction
GO:0071376  cellular response to corticotropin-releasing hormone stimulus
GO:0042755  eating behavior
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0030855  epithelial cell differentiation
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007188  G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0051867  general adaptation syndrome, behavioral process
GO:0009755  hormone-mediated signaling pathway
GO:0060291  long-term synaptic potentiation
GO:0007613  memory
GO:0032099  negative regulation of appetite
GO:0032811  negative regulation of epinephrine secretion
GO:0007218  neuropeptide signaling pathway
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0043306  positive regulation of mast cell degranulation
GO:0048167  regulation of synaptic plasticity
GO:0001666  response to hypoxia
GO:0006950  response to stress
GO:0007165  signal transduction
GO:0008542  visual learning

Cellular Component

GO:0045177  apical part of cell
GO:0033267  axon part
GO:0043025  cell soma
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005771  multivesicular body
GO:0005886  plasma membrane
GO:0005802  trans-Golgi network
GO:0031982  vesicle

Molecular Function

GO:0015056  corticotrophin-releasing factor receptor activity
GO:0051424  corticotropin-releasing hormone binding
GO:0043404  corticotropin-releasing hormone receptor activity
GO:0001965  G-protein alpha-subunit binding
GO:0004930  G-protein coupled receptor activity
GO:0042277  peptide binding
GO:0032403  protein complex binding
GO:0004871  signal transducer activity
GO:0004888  transmembrane receptor activity