colony stimulating factor 1 receptor

詳細情報を見る

同義遺伝子名

Fms, CSF-1-R, Fim-2, Csfmr, AI323359, CD115 antigen, Csf1r, Fms proto-oncogene, c-fms, CD115, M-CSFR, CSF-1R, colony stimulating factor 1 receptor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.80 小脳:18.40 脳幹:- 脳梁:- 松果体:257.80 末梢神経:267.50 脊柱:- 網膜:32.10 目:22.80 動脈:253.20 静脈:- リンパ節:13534.10 末梢血:- 脾臓:895.30 胸腺:49.40 骨髄:141 脂肪:- 骨:325.60 皮膚:7.90
GeneChip 大脳:10.95 小脳:9.36 脳幹:- 脳梁:- 松果体:- 末梢神経:9.05 脊柱:10.49 網膜:10.96 目:9.69 動脈:- 静脈:12.77 リンパ節:13.16 末梢血:- 脾臓:12.97 胸腺:- 骨髄:11.67 脂肪:11.22 骨:12.21 皮膚:11.03
CAGE 大脳:3.97 小脳:- 脳幹:4.39 脳梁:- 松果体:- 末梢神経:- 脊柱:4.64 網膜:- 目:- 動脈:4.62 静脈:- リンパ節:5.63 末梢血:- 脾臓:5.90 胸腺:3.98 骨髄:- 脂肪:- 骨:4.86 皮膚:5.10
RNA-seq 大脳:13.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:248.50 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:32.70 腸:- 結腸:52.90     肝臓:63.40        肺:60.30    膀胱:66.20 腎臓:32.20 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:62 唾液腺:-
GeneChip 子宮:10.94 胎盤:13.85 前立腺:9.61 卵巣:10.59 精巣:7.80 心臓:10.92 骨格筋:9.80 食道:- 胃:9.61 腸:9.74 結腸:- 肝臓:10.75 肺:11.38 膀胱:11.19 腎臓:10.41 下垂体:8.32 甲状腺:- 副腎:10.73 膵臓:10.23 乳腺:11.19 唾液腺:9.80
CAGE 子宮:4.18 胎盤:5.66 前立腺:3.16 卵巣:3.93 精巣:1.89 心臓:- 骨格筋:- 食道:- 胃:3.67 腸:4.13 結腸:4.43     肝臓:4.99    肺:4.47 膀胱:4.47 腎臓:- 下垂体:3.30 甲状腺:- 副腎:4.33 膵臓:3.71 乳腺:4.36 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.33 食道:- 胃:- 腸:- 結腸:-     肝臓:6.03        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001037859
Gene ID 12978
Unigene ID Mm.22574
Probe set ID 1419872_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024621

オーソログ対応遺伝子

ヒト[1]  NM_005211
ラット[1]  NM_001029901

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1302014
1314163
1354640
1354644
1372092
1374350
1427864
1643308
1660841
1673105
1679325
1710023
1840281
2160591
2172781
2408759
2456920
2554332
2567264
2902233
2905686
2963140
2966922
3066742
3110291
3464762
6289129
6364482
6641714
7542761
7626889
7669676
7745707
7894173
7962166
8007983
8094303
8094988
8095010
8099512
8207122
8262059
8390965
8415751
8441691
8497248
8499630
8632916
8661696
8706013
8777716
8786318
8896402
8981357
8981363
9176397
9180904
9324354
9372970
9421432
9590173
9593684
9611252
9811459
9823776
9852586
9893162
10330148
10330270
10349636
10381505
10438963
10529424
10556427
10585470
10597251
10679268
10981960
11027604
11027835
11042159
11076861
11114734
11217851
11698278
11698502
11756160
11796577
11964285
12101129
12223521
12381783
12466851
12477932
12517946
12540842
12614284
12618529
14749363
14767486
15073037
15178709
15215307
15297464
15312244
15483629
15489334
15580571
15616565
15860730
15914564
16081819
16141072
16141073
16172397
16444257
16600665
16602821
16705167
16823860
16877523
16925795
16944957
17116688
17121910
17353186
17420256
17438263
17512498
17932563
17967422
18287559
18328744
18375440
18519746
18523268
18691974
18814279
19017797
19059913
19109221
19219684
19273628
19339695
19733489
19772887
19966810
20008303
20008528
20035012
20123678
20181277
20388654
20418886
20489731
20504948
20571037
20581147
20647008
20682855
20803546
20966214
21041311
21141543
21267068
21549805
21610095
21677750
21727904
21930791
22046273
22084313
22129827
22153499
22294205
22375015
22451653
22516201
22542597
22565823
22573666
22575736
22579672
22749353
22826234
23144792
23177320
23296467
23314290
23383005
23418320
23451116
23575636
23956422
24052571
24056773
24378336
24742461

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0045217  cell-cell junction maintenance
GO:0071345  cellular response to cytokine stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0030097  hemopoiesis
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030316  osteoclast differentiation
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0046488  phosphatidylinositol metabolic process
GO:0048015  phosphoinositide-mediated signaling
GO:0016310  phosphorylation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0090197  positive regulation of chemokine secretion
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045672  positive regulation of osteoclast differentiation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0045124  regulation of bone resorption
GO:0008360  regulation of cell shape
GO:0031529  ruffle organization
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0019955  cytokine binding
GO:0016301  kinase activity
GO:0005011  macrophage colony stimulating factor receptor activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0019903  protein phosphatase binding
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity