disabled homolog 2 (Drosophila)

同義遺伝子名

AI957090, AA960054, Doc2, D15Wsu122e, Mitogen-responsive phosphoprotein, 5730435J12Rik, Dab2, p96, Disabled homolog 2, Doc-2, disabled homolog 2 (Drosophila), DOC-2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:48.60

小脳:165.80

脳幹:63.60

脳梁:-

松果体:257.80

末梢神経:19.10

脊柱:-

網膜:32.10

目:38

動脈:168.80

静脈:-

リンパ節:118.80

末梢血:14.40

脾臓:144.80

胸腺:29.60

骨髄:141

脂肪:850.90

骨:212.90

皮膚:71.30

GeneChip

大脳:5.78

小脳:5.73

脳幹:-

脳梁:-

松果体:-

末梢神経:5.98

脊柱:5.70

網膜:5.46

目:6.07

動脈:-

静脈:8.80

リンパ節:7.73

末梢血:-

脾臓:6.09

胸腺:-

骨髄:5.68

脂肪:9.05

骨:6.89

皮膚:6.96

CAGE

大脳:2.98

小脳:-

脳幹:2.99

脳梁:-

松果体:-

末梢神経:-

脊柱:2.71

網膜:-

目:-

動脈:4.96

静脈:-

リンパ節:5.47

末梢血:-

脾臓:1.94

胸腺:2.49

骨髄:-

脂肪:-

骨:2.83

皮膚:4.69

RNA-seq

大脳:3.24

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:745.60

前立腺:-

卵巣:218.30

精巣:59.10

心臓:37.20

骨格筋:71

食道:-

胃:98.20

腸:-

結腸:70.50

肝臓:9.10

肺:100.40

膀胱:198.50

腎臓:491.60

下垂体:284.20

甲状腺:112.50

副腎:424.40

膵臓:9.40

乳腺:182.80

唾液腺:-

GeneChip

子宮:8.18

胎盤:9.34

前立腺:6.65

卵巣:8.59

精巣:6.01

心臓:7.10

骨格筋:6.20

食道:-

胃:6.10

腸:5.94

結腸:-

肝臓:6.32

肺:7.71

膀胱:8.62

腎臓:10.35

下垂体:6.14

甲状腺:-

副腎:10.79

膵臓:6.70

乳腺:8.11

唾液腺:6.66

CAGE

子宮:4.22

胎盤:4.47

前立腺:2.88

卵巣:4.75

精巣:2.85

心臓:-

骨格筋:-

食道:-

胃:3.91

腸:2.54

結腸:2.53

肝臓:3.36

肺:4.28

膀胱:4.75

腎臓:-

下垂体:2.89

甲状腺:-

副腎:6.52

膵臓:3.97

乳腺:6.34

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.93

食道:-

胃:-

腸:-

結腸:-

肝臓:2.13

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001037905
Gene ID	13132
Unigene ID	Mm.240830
Probe set ID	1423805_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022150

オーソログ対応遺伝子

ヒト[4]	NM_001343
ラット [0]

染色体

15A1 [6,249,788 - 6,390,712]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR006020	Phosphotyrosine interaction domain
IPR011993	Pleckstrin homology-type

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0007257	activation of JUN kinase activity
GO:0006915	apoptosis
GO:0030154	cell differentiation
GO:0000904	cell morphogenesis involved in differentiation
GO:0071364	cellular response to epidermal growth factor stimulus
GO:0048268	clathrin coat assembly
GO:0006897	endocytosis
GO:0007492	endoderm development
GO:0007588	excretion
GO:0001701	in utero embryonic development
GO:0007275	multicellular organismal development
GO:0060766	negative regulation of androgen receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0030308	negative regulation of cell growth
GO:0050680	negative regulation of epithelial cell proliferation
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0010977	negative regulation of neuron projection development
GO:0032091	negative regulation of protein binding
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0006907	pinocytosis
GO:0032349	positive regulation of aldosterone biosynthetic process
GO:0045785	positive regulation of cell adhesion
GO:0030335	positive regulation of cell migration
GO:0045807	positive regulation of endocytosis
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0001921	positive regulation of receptor recycling
GO:0032968	positive regulation of RNA elongation from RNA polymerase II promoter
GO:0060391	positive regulation of SMAD protein nuclear translocation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0015031	protein transport
GO:0006898	receptor-mediated endocytosis
GO:0048545	response to steroid hormone stimulus
GO:0006810	transport
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0016324	apical plasma membrane
GO:0030132	clathrin coat of coated pit
GO:0030665	clathrin coated vesicle membrane
GO:0005905	coated pit
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0016020	membrane
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0070022	transforming growth factor beta receptor complex

Molecular Function

GO:0030276	clathrin binding
GO:0005178	integrin binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0035091	phosphoinositide binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0046332	SMAD binding

disabled homolog 2 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function