Eph receptor A2

詳細情報を見る

同義遺伝子名

AW545284, Sek-2, Ephrin type-A receptor 2 precursor, Myk2, Eck, Tyrosine-protein kinase receptor ECK, SEK-2, Epha2, Eph receptor A2, Sek2, Epithelial cell kinase, MPK-5

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:10.80 末梢血:- 脾臓:65.80 胸腺:9.90 骨髄:- 脂肪:- 骨:37.60 皮膚:-
GeneChip 大脳:5.70 小脳:6 脳幹:- 脳梁:- 松果体:- 末梢神経:5.64 脊柱:5.82 網膜:5.90 目:7.31 動脈:- 静脈:6.62 リンパ節:6.28 末梢血:- 脾臓:6.25 胸腺:- 骨髄:6.43 脂肪:6.11 骨:6.54 皮膚:7.49
CAGE 大脳:0.13 小脳:- 脳幹:0.87 脳梁:- 松果体:- 末梢神経:- 脊柱:0.17 網膜:- 目:- 動脈:1.28 静脈:- リンパ節:0.23 末梢血:- 脾臓:0.52 胸腺:0 骨髄:- 脂肪:- 骨:1.02 皮膚:2.66
RNA-seq 大脳:0.93 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:55.20 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:20.10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:3.30 唾液腺:-
GeneChip 子宮:6.53 胎盤:6.45 前立腺:6.10 卵巣:5.79 精巣:6.07 心臓:6.36 骨格筋:6.12 食道:- 胃:7.65 腸:7.43 結腸:- 肝臓:7.26 肺:7.95 膀胱:6.80 腎臓:6.17 下垂体:6.05 甲状腺:- 副腎:6.67 膵臓:6.11 乳腺:6.26 唾液腺:6.77
CAGE 子宮:1.54 胎盤:1.64 前立腺:0.20 卵巣:0.69 精巣:0 心臓:- 骨格筋:- 食道:- 胃:2.16 腸:3.06 結腸:3.03     肝臓:2.32    肺:2.52 膀胱:1.94 腎臓:- 下垂体:0.29 甲状腺:- 副腎:1.89 膵臓:1.30 乳腺:1.28 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.28 食道:- 胃:- 腸:- 結腸:-     肝臓:1.98        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010139
Gene ID 13836
Unigene ID Mm.258105
Probe set ID 1421151_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000006445

オーソログ対応遺伝子

ヒト[1]  NM_004431
ラット[1]  NM_001108977

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032863  activation of Rac GTPase activity
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0048320  axial mesoderm formation
GO:0001568  blood vessel development
GO:0046849  bone remodeling
GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0007155  cell adhesion
GO:0060326  cell chemotaxis
GO:0030154  cell differentiation
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0048013  ephrin receptor signaling pathway
GO:0030216  keratinocyte differentiation
GO:0070309  lens fiber cell morphogenesis
GO:0033598  mammary gland epithelial cell proliferation
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0021915  neural tube development
GO:0030182  neuron differentiation
GO:0060035  notochord cell development
GO:0014028  notochord formation
GO:0048570  notochord morphogenesis
GO:0001649  osteoblast differentiation
GO:0030316  osteoclast differentiation
GO:0016310  phosphorylation
GO:0090004  positive regulation of establishment of protein localization in plasma membrane
GO:0006468  protein amino acid phosphorylation
GO:0043491  protein kinase B signaling cascade
GO:0045765  regulation of angiogenesis
GO:0043535  regulation of blood vessel endothelial cell migration
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0010591  regulation of lamellipodium assembly
GO:0070848  response to growth factor stimulus
GO:0001501  skeletal system development
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001570  vasculogenesis

Cellular Component

GO:0030054  cell junction
GO:0042995  cell projection
GO:0005925  focal adhesion
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0031256  leading edge membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005003  ephrin receptor activity
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity