estrogen receptor 2 (beta)

詳細情報を見る

同義遺伝子名

ERbeta, Estrogen receptor beta, Estrb, Esr2, ER[b], oestrogen receptor beta, Nr3a2, estrogen receptor 2 (beta), ER-beta, ER beta

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:196.20 小脳:73.70 脳幹:190.70 脳梁:- 松果体:257.80 末梢神経:152.90 脊柱:47.30 網膜:225 目:326.70 動脈:84.40 静脈:- リンパ節:97.20 末梢血:43.10 脾臓:105.30 胸腺:247 骨髄:128.20 脂肪:- 骨:263 皮膚:197.90
GeneChip 大脳:4.85 小脳:5.04 脳幹:- 脳梁:- 松果体:- 末梢神経:4.89 脊柱:5.09 網膜:4.69 目:4.97 動脈:- 静脈:4.72 リンパ節:4.60 末梢血:- 脾臓:4.71 胸腺:- 骨髄:5.02 脂肪:4.93 骨:4.75 皮膚:4.95
CAGE 大脳:0.18 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0.17 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0.29
RNA-seq 大脳:1.99 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:82.80 前立腺:30.90 卵巣:91.90 精巣:192.10 心臓:93 骨格筋:71 食道:- 胃:98.20 腸:- 結腸:70.50     肝臓:90.50        肺:70.30    膀胱:198.50 腎臓:153.10 下垂体:258.30 甲状腺:- 副腎:- 膵臓:28.10 乳腺:140.40 唾液腺:54
GeneChip 子宮:4.60 胎盤:4.81 前立腺:5.82 卵巣:7.55 精巣:5.01 心臓:5.16 骨格筋:5.45 食道:- 胃:4.74 腸:4.84 結腸:- 肝臓:4.96 肺:5.15 膀胱:5.15 腎臓:5.19 下垂体:5.14 甲状腺:- 副腎:4.55 膵臓:5.43 乳腺:4.83 唾液腺:5.31
CAGE 子宮:1.16 胎盤:0.11 前立腺:1.80 卵巣:4.69 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0.47    肺:2.01 膀胱:0.46 腎臓:- 下垂体:0 甲状腺:- 副腎:0 膵臓:0 乳腺:0.20 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.24 食道:- 胃:- 腸:- 結腸:-     肝臓:1.03        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_207707
Gene ID 13983
Unigene ID Mm.25610
Probe set ID 1426103_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021055

オーソログ対応遺伝子

ヒト[18]  NM_001040275, NM_001040276, NM_001214902, NM_001214903, NM_001437
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8977441
9027582
9058381
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001662  behavioral fear response
GO:0007420  brain development
GO:0071392  cellular response to estradiol stimulus
GO:0060743  epithelial cell maturation involved in prostate gland development
GO:0030520  estrogen receptor signaling pathway
GO:0008628  induction of apoptosis by hormones
GO:0007611  learning or memory
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0048521  negative regulation of behavior
GO:0060548  negative regulation of cell death
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001764  neuron migration
GO:0001541  ovarian follicle development
GO:0045742  positive regulation of epidermal growth factor receptor signaling pathway
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060740  prostate gland epithelium morphogenesis
GO:0042127  regulation of cell proliferation
GO:0043523  regulation of neuron apoptosis
GO:0006355  regulation of transcription, DNA-dependent
GO:0032355  response to estradiol stimulus
GO:0033574  response to testosterone stimulus
GO:0060011  Sertoli cell proliferation
GO:0043401  steroid hormone mediated signaling pathway
GO:0030518  steroid hormone receptor signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0060065  uterus development
GO:0060068  vagina development

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0003677  DNA binding
GO:0019899  enzyme binding
GO:0030284  estrogen receptor activity
GO:0034056  estrogen response element binding
GO:0042562  hormone binding
GO:0008289  lipid binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0005496  steroid binding
GO:0003707  steroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding