PTK2 protein tyrosine kinase 2

詳細情報を見る

同義遺伝子名

mKIAA4203, pp125FAK, Fak, Ptk2, Fadk, FRNK, PTK2 protein tyrosine kinase 2, FADK 1, Fak1, Focal adhesion kinase 1, FAK, KIAA4203

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:156.30 小脳:202.60 脳幹:127.10 脳梁:- 松果体:- 末梢神経:76.40 脊柱:236.40 網膜:96.40 目:121.60 動脈:168.80 静脈:- リンパ節:- 末梢血:14.40 脾臓:39.50 胸腺:88.90 骨髄:- 脂肪:- 骨:100.20 皮膚:63.30
GeneChip 大脳:3.97 小脳:3.76 脳幹:- 脳梁:- 松果体:- 末梢神経:3.68 脊柱:3.61 網膜:3.38 目:3.45 動脈:- 静脈:3.94 リンパ節:3.71 末梢血:- 脾臓:3.55 胸腺:- 骨髄:3.54 脂肪:3.76 骨:3.39 皮膚:3.44
CAGE 大脳:3.75 小脳:- 脳幹:3.36 脳梁:- 松果体:- 末梢神経:- 脊柱:3.35 網膜:- 目:- 動脈:3.43 静脈:- リンパ節:3.10 末梢血:- 脾臓:2.51 胸腺:1.85 骨髄:- 脂肪:- 骨:2.45 皮膚:3.17
RNA-seq 大脳:6.22 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:174.50 胎盤:82.80 前立腺:- 卵巣:160.90 精巣:110.80 心臓:111.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:52.90     肝臓:-        肺:170.70    膀胱:66.20 腎臓:40.30 下垂体:- 甲状腺:112.50 副腎:- 膵臓:18.80 乳腺:94.70 唾液腺:-
GeneChip 子宮:3.79 胎盤:4.26 前立腺:3.72 卵巣:3.91 精巣:3.69 心臓:3.60 骨格筋:3.78 食道:- 胃:3.70 腸:3.72 結腸:- 肝臓:3.81 肺:4.11 膀胱:3.77 腎臓:3.59 下垂体:3.93 甲状腺:- 副腎:3.53 膵臓:3.80 乳腺:3.73 唾液腺:3.60
CAGE 子宮:3.86 胎盤:3.95 前立腺:3.34 卵巣:3.64 精巣:3.00 心臓:- 骨格筋:- 食道:- 胃:2.36 腸:3.37 結腸:3.26     肝臓:3.31    肺:4.15 膀胱:3.07 腎臓:- 下垂体:3.42 甲状腺:- 副腎:3.33 膵臓:3.32 乳腺:3.87 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.91 食道:- 胃:- 腸:- 結腸:-     肝臓:2.56        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007982
Gene ID 14083
Unigene ID Mm.254494
Probe set ID 1430827_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022607

オーソログ対応遺伝子

ヒト[4]  NM_001199649, NM_005607, NM_153831
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1458538
1528852
2132399
7478517
7479864
7487975
7529876
7566154
7685911
7726850
7766995
7997267
8562954
8816475
8843417
9032297
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9226367
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9750131
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10066258
10332027
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10366455
10409670
10413676
10417825
10431817
10699171
10742111
10896938
10922068
10967115
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11114734
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16533505
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17197095
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17409352
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19451276
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20082310
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20205236
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24089517
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24260201
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24809783

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0001568  blood vessel development
GO:0030644  cellular chloride ion homeostasis
GO:0006928  cellular component movement
GO:0021955  central nervous system neuron axonogenesis
GO:0043542  endothelial cell migration
GO:0048013  ephrin receptor signaling pathway
GO:0040023  establishment of nucleus localization
GO:0030198  extracellular matrix organization
GO:0060396  growth hormone receptor signaling pathway
GO:0007229  integrin-mediated signaling pathway
GO:0007254  JNK cascade
GO:0000165  MAPKKK cascade
GO:0000226  microtubule cytoskeleton organization
GO:0007275  multicellular organismal development
GO:0043066  negative regulation of apoptosis
GO:0050771  negative regulation of axonogenesis
GO:0030336  negative regulation of cell migration
GO:0022408  negative regulation of cell-cell adhesion
GO:0046621  negative regulation of organ growth
GO:0051964  negative regulation of synaptogenesis
GO:0001764  neuron migration
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0045785  positive regulation of cell adhesion
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0060252  positive regulation of glial cell proliferation
GO:0050766  positive regulation of phagocytosis
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0050806  positive regulation of synaptic transmission
GO:0045909  positive regulation of vasodilation
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0042127  regulation of cell proliferation
GO:0008360  regulation of cell shape
GO:0045667  regulation of osteoblast differentiation
GO:0007172  signal complex assembly
GO:0001570  vasculogenesis

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005925  focal adhesion
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0042383  sarcolemma

Molecular Function

GO:0003779  actin binding
GO:0005524  ATP binding
GO:0005178  integrin binding
GO:0008432  JUN kinase binding
GO:0016301  kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0000166  nucleotide binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004713  protein tyrosine kinase activity
GO:0042169  SH2 domain binding
GO:0004871  signal transducer activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups