fibroblast growth factor receptor 2

同義遺伝子名

fibroblast growth factor receptor 2, FGFR-2, CD332 antigen, AW556123, MGC102519, Ect1, Fgfr-7, Fgfr7, Bek, Fgfr2, Fibroblast growth factor receptor 2 precursor, Keratinocyte growth factor receptor, KGFRTr, Fgfr-2, AU043015

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:78.10

小脳:73.70

脳幹:158.90

脳梁:-

松果体:-

末梢神経:114.70

脊柱:141.90

網膜:-

目:60.80

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:39.50

骨髄:-

脂肪:212.70

骨:125.20

皮膚:79.20

GeneChip

大脳:8.57

小脳:9.29

脳幹:-

脳梁:-

松果体:-

末梢神経:6.67

脊柱:9.87

網膜:8.75

目:10.06

動脈:-

静脈:9.16

リンパ節:6.54

末梢血:-

脾臓:6.63

胸腺:-

骨髄:7.23

脂肪:7.78

骨:8.48

皮膚:10.80

CAGE

大脳:2.39

小脳:-

脳幹:2.73

脳梁:-

松果体:-

末梢神経:-

脊柱:3.26

網膜:-

目:-

動脈:1.80

静脈:-

リンパ節:1.20

末梢血:-

脾臓:0.52

胸腺:0.95

骨髄:-

脂肪:-

骨:1.51

皮膚:3.42

RNA-seq

大脳:4.58

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:305.40

胎盤:96.70

前立腺:92.60

卵巣:68.90

精巣:59.10

心臓:-

骨格筋:-

食道:-

胃:32.70

腸:-

結腸:17.60

肝臓:-

肺:70.30

膀胱:-

腎臓:72.50

下垂体:12.90

甲状腺:112.50

副腎:-

膵臓:37.50

乳腺:2638

唾液腺:324

GeneChip

子宮:10.03

胎盤:9.06

前立腺:8.85

卵巣:9.43

精巣:7.21

心臓:6.83

骨格筋:6.80

食道:-

胃:10.33

腸:9.15

結腸:-

肝臓:8.39

肺:10.43

膀胱:10.12

腎臓:8.01

下垂体:6.84

甲状腺:-

副腎:11.21

膵臓:7.35

乳腺:8.58

唾液腺:9.20

CAGE

子宮:3.29

胎盤:3.04

前立腺:2.57

卵巣:3.14

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:2.44

腸:2.19

結腸:2.85

肝臓:2.64

肺:3.93

膀胱:3.14

腎臓:-

下垂体:0.99

甲状腺:-

副腎:4.17

膵臓:1.61

乳腺:1.50

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.32

食道:-

胃:-

腸:-

結腸:-

肝臓:3.46

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_201601
Gene ID	14183
Unigene ID	Mm.16340
Probe set ID	1433489_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000030849

オーソログ対応遺伝子

ヒト[37]	NM_000141, NM_001144913, NM_001144914, NM_001144915, NM_001144916, NM_001144917, NM_001144918, NM_001144919, NM_022970
ラット[18]	NM_001109892, NM_001109893, NM_001109894, NM_001109895, NM_001109896, NM_012712, NM_001144918, NM_001144919, NM_022970

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0007409	axonogenesis
GO:0060348	bone development
GO:0030282	bone mineralization
GO:0060349	bone morphogenesis
GO:0060667	branch elongation involved in salivary gland morphogenesis
GO:0060670	branching involved in embryonic placenta morphogenesis
GO:0060442	branching involved in prostate gland morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0048755	branching morphogenesis of a nerve
GO:0060449	bud elongation involved in lung branching
GO:0045165	cell fate commitment
GO:0007267	cell-cell signaling
GO:0060365	coronal suture morphogenesis
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048557	embryonic digestive tract morphogenesis
GO:0048568	embryonic organ development
GO:0048562	embryonic organ morphogenesis
GO:0009880	embryonic pattern specification
GO:0048730	epidermis morphogenesis
GO:0030855	epithelial cell differentiation
GO:0050673	epithelial cell proliferation
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0001837	epithelial to mesenchymal transition
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0022612	gland morphogenesis
GO:0048565	gut development
GO:0031069	hair follicle morphogenesis
GO:0001701	in utero embryonic development
GO:0042472	inner ear morphogenesis
GO:0032808	lacrimal gland development
GO:0060601	lateral sprouting from an epithelium
GO:0070307	lens fiber cell development
GO:0060174	limb bud formation
GO:0048286	lung alveolus development
GO:0030324	lung development
GO:0060463	lung lobe morphogenesis
GO:0060484	lung-associated mesenchyme development
GO:0060615	mammary gland bud formation
GO:0003149	membranous septum morphogenesis
GO:0048762	mesenchymal cell differentiation
GO:0060915	mesenchymal cell differentiation involved in lung development
GO:0060916	mesenchymal cell proliferation involved in lung development
GO:0030901	midbrain development
GO:0016331	morphogenesis of embryonic epithelium
GO:0035264	multicellular organism growth
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0045839	negative regulation of mitosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0021847	neuroblast division in the ventricular zone
GO:0007528	neuromuscular junction development
GO:0042476	odontogenesis
GO:0021769	orbitofrontal cortex development
GO:0035265	organ growth
GO:0009887	organ morphogenesis
GO:0030916	otic vesicle formation
GO:0003148	outflow tract septum morphogenesis
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0045787	positive regulation of cell cycle
GO:0051781	positive regulation of cell division
GO:0008284	positive regulation of cell proliferation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0010518	positive regulation of phospholipase activity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0009791	post-embryonic development
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523	prostate epithelial cord elongation
GO:0060512	prostate gland morphogenesis
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0021860	pyramidal neuron development
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0010453	regulation of cell fate commitment
GO:0042127	regulation of cell proliferation
GO:0050678	regulation of epithelial cell proliferation
GO:0070372	regulation of ERK1 and ERK2 cascade
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
GO:0060688	regulation of morphogenesis of a branching structure
GO:0040014	regulation of multicellular organism growth
GO:0051150	regulation of smooth muscle cell differentiation
GO:0008589	regulation of smoothened signaling pathway
GO:0048608	reproductive structure development
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0048489	synaptic vesicle transport
GO:0001657	ureteric bud development
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis
GO:0055010	ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0005938	cell cortex
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0060076	excitatory synapse
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

fibroblast growth factor receptor 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function