fibroblast growth factor receptor 3

同義遺伝子名

Heparin-binding growth factor receptor, Fgfr3, CD333 antigen, Sam3, fibroblast growth factor receptor 3, Fgfr-3, HBGFR, Mfr3, FGFR-3, Fibroblast growth factor receptor 3 precursor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:9.90

骨髄:51.30

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:8.85

小脳:8.43

脳幹:-

脳梁:-

松果体:-

末梢神経:5.24

脊柱:10.22

網膜:6.89

目:7.99

動脈:-

静脈:6.98

リンパ節:5.77

末梢血:-

脾臓:6.90

胸腺:-

骨髄:5.24

脂肪:6.04

骨:6.35

皮膚:9.43

CAGE

大脳:2.63

小脳:-

脳幹:3.23

脳梁:-

松果体:-

末梢神経:-

脊柱:3.70

網膜:-

目:-

動脈:0.54

静脈:-

リンパ節:0

末梢血:-

脾臓:1.06

胸腺:0

骨髄:-

脂肪:-

骨:1.51

皮膚:2.71

RNA-seq

大脳:19.26

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:23

精巣:73.90

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:8.10

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:3.30

唾液腺:-

GeneChip

子宮:5.51

胎盤:5.44

前立腺:7.61

卵巣:6.01

精巣:5.45

心臓:6.21

骨格筋:5.97

食道:-

胃:6.75

腸:6.95

結腸:-

肝臓:7.59

肺:9.90

膀胱:8.31

腎臓:7.89

下垂体:5.05

甲状腺:-

副腎:5.93

膵臓:7.02

乳腺:5.74

唾液腺:5.62

CAGE

子宮:0.74

胎盤:0.69

前立腺:0.63

卵巣:0.94

精巣:0

心臓:-

骨格筋:-

食道:-

胃:1.07

腸:1.05

結腸:1.19

肝臓:2.74

肺:3.28

膀胱:2.14

腎臓:-

下垂体:0.70

甲状腺:-

副腎:0.64

膵臓:1.84

乳腺:0.46

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.58

食道:-

胃:-

腸:-

結腸:-

肝臓:2.58

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001163215
Gene ID	14184
Unigene ID	Mm.69044
Probe set ID	1421841_at [Mouse430_2]
Ensembl ID	ENSMUSG00000054252

オーソログ対応遺伝子

ヒト[6]	NM_000142, NM_001163213, NM_022965
ラット[1]	NM_053429, NM_001163213, NM_022965

染色体

5B2 [34,064,373 - 34,079,716]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0060385	axonogenesis involved in innervation
GO:0070977	bone maturation
GO:0060349	bone morphogenesis
GO:0051216	cartilage development
GO:0030154	cell differentiation
GO:0007267	cell-cell signaling
GO:0090102	cochlea development
GO:0048546	digestive tract morphogenesis
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0030900	forebrain development
GO:0048839	inner ear development
GO:0060113	inner ear receptor cell differentiation
GO:0070307	lens fiber cell development
GO:0002089	lens morphogenesis in camera-type eye
GO:0000165	MAPKKK cascade
GO:0002009	morphogenesis of an epithelium
GO:0022010	myelination in the central nervous system
GO:0048712	negative regulation of astrocyte differentiation
GO:0008285	negative regulation of cell proliferation
GO:0048640	negative regulation of developmental growth
GO:0050680	negative regulation of epithelial cell proliferation
GO:0045839	negative regulation of mitosis
GO:0045879	negative regulation of smoothened signaling pathway
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0014003	oligodendrocyte development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0045597	positive regulation of cell differentiation
GO:0008284	positive regulation of cell proliferation
GO:0001938	positive regulation of endothelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0043525	positive regulation of neuron apoptosis
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0010518	positive regulation of phospholipase activity
GO:0031398	positive regulation of protein ubiquitination
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0048678	response to axon injury
GO:0035019	somatic stem cell maintenance
GO:0021762	substantia nigra development

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0005783	endoplasmic reticulum
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0009898	internal side of plasma membrane
GO:0005764	lysosome
GO:0016020	membrane
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

fibroblast growth factor receptor 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function