connective tissue growth factor

詳細情報を見る

同義遺伝子名

connective tissue growth factor, fisp-12, Ccn2, Ctgf, hypertrophic chondrocyte-specific gene product 24, Fisp12, Hcs24, Fisp-12, Hypertrophic chondrocyte-specific protein 24, Protein FISP-12, Connective tissue growth factor precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:3.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:7.66 小脳:6.65 脳幹:- 脳梁:- 松果体:- 末梢神経:8.54 脊柱:7.31 網膜:8.27 目:10.35 動脈:- 静脈:11.87 リンパ節:5.89 末梢血:- 脾臓:9.93 胸腺:- 骨髄:7.08 脂肪:8.23 骨:9.14 皮膚:11.50
CAGE 大脳:2.86 小脳:- 脳幹:2.90 脳梁:- 松果体:- 末梢神経:- 脊柱:3.19 網膜:- 目:- 動脈:6.76 静脈:- リンパ節:2.38 末梢血:- 脾臓:3.76 胸腺:2.11 骨髄:- 脂肪:- 骨:3.92 皮膚:4.29
RNA-seq 大脳:6.22 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:9.48 胎盤:11.97 前立腺:11.37 卵巣:9.91 精巣:8.66 心臓:11.24 骨格筋:9.37 食道:- 胃:8.27 腸:8.12 結腸:- 肝臓:7.52 肺:11.85 膀胱:12.93 腎臓:10.76 下垂体:8.66 甲状腺:- 副腎:9.60 膵臓:6.78 乳腺:9.28 唾液腺:9.40
CAGE 子宮:3.78 胎盤:5.78 前立腺:3.76 卵巣:4.88 精巣:3.06 心臓:- 骨格筋:- 食道:- 胃:4.08 腸:2.98 結腸:2.60     肝臓:2.60    肺:5.56 膀胱:4.78 腎臓:- 下垂体:3.68 甲状腺:- 副腎:5.03 膵臓:2.33 乳腺:3.78 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.10 食道:- 胃:- 腸:- 結腸:-     肝臓:3.31        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010217
Gene ID 14219
Unigene ID Mm.390287
Probe set ID 1416953_at  [Mouse430_2]
Ensembl ID ENSMUSG00000019997

オーソログ対応遺伝子

ヒト[1]  NM_001901
ラット[1]  NM_022266

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1419914
1888698
2029337
7687569
9135077
9184077
9780329
10082563
10446209
10595311
11031104
11217851
11237711
11973313
12036876
12112457
12297288
12441304
12466851
12477932
12571253
12712324
12736220
12763067
12842083
14633130
15256388
15305294
15315937
15376321
15489334
15496414
15574513
15610731
15699040
15800063
15862142
15980944
15981023
16019426
16141072
16186174
16343439
16380465
16602821
16611331
16710777
16767377
16769906
16889607
17111364
17164417
17197570
17204263
17215322
17239853
17330803
17350707
17362910
17541935
17554073
17625227
17657819
17765657
17804598
17846733
17875658
17890868
18067859
18075496
18089935
18095342
18201696
18213577
18215621
18245842
18276598
18287562
18319604
18474939
18481203
18535099
18554416
18596209
18597638
18632843
18667463
18835464
18840685
18927151
19004856
19008461
19038999
19096030
19111553
19131512
19194549
19255250
19276073
19332661
19364818
19385047
19407155
19409883
19411759
19423687
19498055
19500499
19541844
19565505
19657322
19698122
19707545
19730442
19766716
19817698
19959709
20018872
20019329
20053791
20080568
20133625
20213804
20235153
20333347
20348416
20406330
20430035
20445055
20497571
20534727
20571031
20585662
20615956
20637190
20721934
20877562
20936632
20946117
21121985
21186275
21239535
21267068
21382976
21454550
21491433
21533890
21602138
21654839
21747166
21750040
21826667
21868453
21876171
21913214
21925146
21969300
21978691
22008794
22035642
22043022
22095278
22321187
22363445
22421594
22532143
22542845
22563064
22573622
22611085
22749815
22885106
22913183
22926930
22993071
23048035
23073844
23142580
23175628
23199377
23212098
23284892
23287510
23322166
23322734
23401504
23525012
23530034
23555635
23564449
23571711
23620511
23673415
23741006
23756156
23778361
23816882
23839921
23863479
23868935
23904456
23918385
23950936
23951098
23983074
23985903
23993699
24082083
24115331
24122827
24161906
24217924
24380865
24508728
24627144
24754049

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0001502  cartilage condensation
GO:0007155  cell adhesion
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0007160  cell-matrix adhesion
GO:0060401  cytosolic calcium ion transport
GO:0006260  DNA replication
GO:0070278  extracellular matrix constituent secretion
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007229  integrin-mediated signaling pathway
GO:0030324  lung development
GO:0060548  negative regulation of cell death
GO:0010629  negative regulation of gene expression
GO:0001503  ossification
GO:0060452  positive regulation of cardiac muscle contraction
GO:0043280  positive regulation of caspase activity
GO:0050867  positive regulation of cell activation
GO:0010942  positive regulation of cell death
GO:0045597  positive regulation of cell differentiation
GO:0008284  positive regulation of cell proliferation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0070318  positive regulation of G0 to G1 transition
GO:0010628  positive regulation of gene expression
GO:0046330  positive regulation of JNK cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051496  positive regulation of stress fiber formation
GO:0001558  regulation of cell growth
GO:0032330  regulation of chondrocyte differentiation

Cellular Component

GO:0005938  cell cortex
GO:0005801  cis-Golgi network
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0048471  perinuclear region of cytoplasm
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0001968  fibronectin binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0005520  insulin-like growth factor binding
GO:0005178  integrin binding