FMS-like tyrosine kinase 1

同義遺伝子名

Flt1, Emrk2, Flt, VEGFR1, Embryonic receptor kinase 2, Flt-1, vascular permeability factor receptor, sFlt1, vascular endothelial growth factor receptor, VEGFR-1, Tyrosine-protein kinase receptor FLT, AI323757, FMS-like tyrosine kinase 1, FLT-1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:29.50

小脳:36.80

脳幹:-

脳梁:-

松果体:773.40

末梢神経:-

脊柱:141.90

網膜:-

目:30.40

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:15.80

GeneChip

大脳:5.77

小脳:5.77

脳幹:-

脳梁:-

松果体:-

末梢神経:5

脊柱:6.02

網膜:4.77

目:4.86

動脈:-

静脈:6.75

リンパ節:5.28

末梢血:-

脾臓:5.08

胸腺:-

骨髄:4.81

脂肪:6.49

骨:5.08

皮膚:6.06

CAGE

大脳:3.71

小脳:-

脳幹:4.16

脳梁:-

松果体:-

末梢神経:-

脊柱:4.22

網膜:-

目:-

動脈:4.25

静脈:-

リンパ節:3.21

末梢血:-

脾臓:2.12

胸腺:1.69

骨髄:-

脂肪:-

骨:2.45

皮膚:3.20

RNA-seq

大脳:5.18

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:1146

前立腺:-

卵巣:-

精巣:-

心臓:74.40

骨格筋:142

食道:-

胃:-

腸:-

結腸:35.20

肝臓:-

肺:90.40

膀胱:-

腎臓:40.30

下垂体:-

甲状腺:-

副腎:-

膵臓:131.40

乳腺:42.40

唾液腺:-

GeneChip

子宮:5.75

胎盤:12.15

前立腺:4.99

卵巣:5.22

精巣:5.22

心臓:6.98

骨格筋:6.36

食道:-

胃:5.29

腸:5.14

結腸:-

肝臓:5.38

肺:7.03

膀胱:5.30

腎臓:6.02

下垂体:5.17

甲状腺:-

副腎:5.80

膵臓:5.56

乳腺:6.17

唾液腺:5.09

CAGE

子宮:3.21

胎盤:5.99

前立腺:1.97

卵巣:3.15

精巣:0

心臓:-

骨格筋:-

食道:-

胃:3.39

腸:2.79

結腸:2.74

肝臓:2.74

肺:4.78

膀胱:3.23

腎臓:-

下垂体:2.79

甲状腺:-

副腎:4.41

膵臓:3.74

乳腺:3.15

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.86

食道:-

胃:-

腸:-

結腸:-

肝臓:2.73

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010228
Gene ID	14254
Unigene ID	Mm.389712
Probe set ID	1454037_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000029648

オーソログ対応遺伝子

ヒト[4]	NM_001159920, NM_001160030, NM_001160031, NM_002019
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain
IPR009134	Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal
IPR009135	Tyrosine-protein kinase, vascular endothelial growth factor receptor 1 (VEGFR1), N-terminal

遺伝子オントロジー (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001525	angiogenesis
GO:0048514	blood vessel morphogenesis
GO:0030154	cell differentiation
GO:0016477	cell migration
GO:0006935	chemotaxis
GO:0048598	embryonic morphogenesis
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0002548	monocyte chemotaxis
GO:0007275	multicellular organismal development
GO:0001569	patterning of blood vessels
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0045766	positive regulation of angiogenesis
GO:0030335	positive regulation of cell migration
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0010863	positive regulation of phospholipase C activity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0006940	regulation of smooth muscle contraction
GO:0001666	response to hypoxia
GO:0002040	sprouting angiogenesis
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0048010	vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0019838	growth factor binding
GO:0042802	identical protein binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005021	vascular endothelial growth factor receptor activity

FMS-like tyrosine kinase 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function