toll-like receptor 3

詳細情報を見る

同義遺伝子名

AI957183, Toll-like receptor 3 precursor, toll-like receptor 3, Tlr3, CD283 antigen

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:6.90

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:172

脊柱:-

網膜:-

目:7.60

動脈:-

静脈:-

リンパ節:162

末梢血:-

脾臓:118.50

胸腺:-

骨髄:12.80

脂肪:-

骨:12.50

皮膚:7.90

GeneChip

大脳:5.89

小脳:5.62

脳幹:-

脳梁:-

松果体:-

末梢神経:5.45

脊柱:6.47

網膜:6.50

目:7.02

動脈:-

静脈:4.94

リンパ節:7.06

末梢血:-

脾臓:6.62

胸腺:-

骨髄:4.71

脂肪:6.35

骨:5.43

皮膚:6.39

CAGE

大脳:1.52

小脳:-

脳幹:1.85

脳梁:-

松果体:-

末梢神経:-

脊柱:2.25

網膜:-

目:-

動脈:2.67

静脈:-

リンパ節:3.23

末梢血:-

脾臓:1.52

胸腺:1.26

骨髄:-

脂肪:-

骨:1.02

皮膚:2.56

RNA-seq

大脳:1.16

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:34.50

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:20.10

膀胱:66.20

腎臓:-

下垂体:64.60

甲状腺:-

副腎:-

膵臓:-

乳腺:42.40

唾液腺:-

GeneChip

子宮:6.69

胎盤:5.83

前立腺:6.91

卵巣:6.08

精巣:4.57

心臓:6.29

骨格筋:5.40

食道:-

胃:6.61

腸:7.75

結腸:-

肝臓:5.97

肺:7.17

膀胱:7.18

腎臓:6.15

下垂体:5.68

甲状腺:-

副腎:6.45

膵臓:5.15

乳腺:6.82

唾液腺:7.58

CAGE

子宮:2.68

胎盤:1.86

前立腺:1.91

卵巣:2.00

精巣:0

心臓:-

骨格筋:-

食道:-

胃:2.36

腸:3.34

結腸:3.39

肝臓:1.64

肺:2.34

膀胱:2.74

腎臓:-

下垂体:2.18

甲状腺:-

副腎:1.87

膵臓:0.84

乳腺:3.23

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.15

食道:-

胃:-

腸:-

結腸:-

肝臓:2.03

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_126166
Gene ID	142980
Unigene ID	Mm.33874
Probe set ID	1422782_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031639

オーソログ対応遺伝子

ヒト[1]	NM_003265
ラット[1]	NM_198791

染色体

遺伝子ファミリー (Interpro ID)

IPR000157

Toll-Interleukin receptor

遺伝子オントロジー (GO ID)

Biological Process

GO:0071360	cellular response to exogenous dsRNA
GO:0006952	defense response
GO:0051607	defense response to virus
GO:0007252	I-kappaB phosphorylation
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002282	microglial cell activation during immune response
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0045080	positive regulation of chemokine biosynthetic process
GO:0032722	positive regulation of chemokine production
GO:0001819	positive regulation of cytokine production
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729	positive regulation of inflammatory response
GO:0045356	positive regulation of interferon-alpha biosynthetic process
GO:0045359	positive regulation of interferon-beta biosynthetic process
GO:0032728	positive regulation of interferon-beta production
GO:0045078	positive regulation of interferon-gamma biosynthetic process
GO:0032735	positive regulation of interleukin-12 production
GO:0032755	positive regulation of interleukin-6 production
GO:0032757	positive regulation of interleukin-8 production
GO:0046330	positive regulation of JNK cascade
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0034123	positive regulation of toll-like receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032760	positive regulation of tumor necrosis factor production
GO:0032481	positive regulation of type I interferon production
GO:0034346	positive regulation of type III interferon production
GO:0043331	response to dsRNA
GO:0043330	response to exogenous dsRNA
GO:0009615	response to virus
GO:0007165	signal transduction
GO:0034138	toll-like receptor 3 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005768	endosome
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0016020	membrane

Molecular Function

GO:0003725	double-stranded RNA binding
GO:0005515	protein binding
GO:0004872	receptor activity
GO:0003723	RNA binding
GO:0004888	transmembrane receptor activity

toll-like receptor 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function