X-ray repair complementing defective repair in Chinese hamster cells 6

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同義遺伝子名

Ku70, CTC75, Ku p70, Xrcc6, CTC box-binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, G22p1, ATP-dependent DNA helicase 2 subunit 1, DNA-repair protein XRCC6, Ku autoantigen protein p70 homolog, CTCBF

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:38.20 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:64.30 目:45.60 動脈:84.40 静脈:- リンパ節:32.40 末梢血:129.40 脾臓:39.50 胸腺:276.60 骨髄:12.80 脂肪:- 骨:50.10 皮膚:31.70
GeneChip 大脳:6.47 小脳:6.81 脳幹:- 脳梁:- 松果体:- 末梢神経:6.78 脊柱:6.71 網膜:7.62 目:6.95 動脈:- 静脈:7.27 リンパ節:7.69 末梢血:- 脾臓:7.43 胸腺:- 骨髄:9.19 脂肪:8.24 骨:8.80 皮膚:6.85
CAGE 大脳:2.83 小脳:- 脳幹:2.73 脳梁:- 松果体:- 末梢神経:- 脊柱:2.48 網膜:- 目:- 動脈:4.09 静脈:- リンパ節:3.34 末梢血:- 脾臓:3.53 胸腺:5.18 骨髄:- 脂肪:- 骨:3.81 皮膚:2.82
RNA-seq 大脳:2.54 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:82.80 前立腺:61.80 卵巣:23 精巣:29.60 心臓:- 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:17.60     肝臓:18.10        肺:70.30    膀胱:- 腎臓:8.10 下垂体:12.90 甲状腺:- 副腎:- 膵臓:103.20 乳腺:81.60 唾液腺:-
GeneChip 子宮:7.79 胎盤:6.49 前立腺:7.45 卵巣:7.68 精巣:7.41 心臓:7.39 骨格筋:8.14 食道:- 胃:7.14 腸:7.25 結腸:- 肝臓:7.49 肺:6.59 膀胱:7.23 腎臓:7.02 下垂体:7.23 甲状腺:- 副腎:7.91 膵臓:6.82 乳腺:7.70 唾液腺:7.36
CAGE 子宮:3.07 胎盤:2.55 前立腺:2.81 卵巣:3.14 精巣:3.31 心臓:- 骨格筋:- 食道:- 胃:3.13 腸:2.92 結腸:2.85     肝臓:2.76    肺:2.41 膀胱:2.70 腎臓:- 下垂体:3.05 甲状腺:- 副腎:3.31 膵臓:2.66 乳腺:3.04 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:4.96 食道:- 胃:- 腸:- 結腸:-     肝臓:5.23        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0071475  cellular hyperosmotic salinity response
GO:0071481  cellular response to X-ray
GO:0006310  DNA recombination
GO:0006281  DNA repair
GO:0006302  double-strand break repair
GO:0006303  double-strand break repair via nonhomologous end joining
GO:0008152  metabolic process
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0050769  positive regulation of neurogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006355  regulation of transcription, DNA-dependent
GO:0006974  response to DNA damage stimulus
GO:0010212  response to ionizing radiation
GO:0000723  telomere maintenance
GO:0006351  transcription, DNA-dependent
GO:0033151  V(D)J recombination

Cellular Component

GO:0005694  chromosome
GO:0005737  cytoplasm
GO:0043564  Ku70:Ku80 complex
GO:0070419  nonhomologous end joining complex
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0051575  5'-deoxyribose-5-phosphate lyase activity
GO:0005524  ATP binding
GO:0004003  ATP-dependent DNA helicase activity
GO:0003824  catalytic activity
GO:0003684  damaged DNA binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0003691  double-stranded telomeric DNA binding
GO:0004386  helicase activity
GO:0016787  hydrolase activity
GO:0016829  lyase activity
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0008022  protein C-terminus binding
GO:0042162  telomeric DNA binding