gap junction protein, alpha 1

詳細情報を見る

同義遺伝子名

Gja1, connexin 43, gap junction membrane channel protein alpha 1, alpha 1 connexin, Npm1, Cx43, Cnx43, Gap junction 43 kDa heart protein, Cxn-43, connexin43, Gap junction alpha-1 protein, Cx43alpha1, Gja-1, Connexin-43, AU042049, AW546267

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:356 小脳:110.50 脳幹:190.70 脳梁:- 松果体:- 末梢神経:133.80 脊柱:236.40 網膜:96.40 目:144.40 動脈:84.40 静脈:- リンパ節:- 末梢血:14.40 脾臓:184.30 胸腺:9.90 骨髄:25.60 脂肪:- 骨:187.90 皮膚:332.50
GeneChip 大脳:9.40 小脳:9.19 脳幹:- 脳梁:- 松果体:- 末梢神経:6 脊柱:10.24 網膜:4.80 目:5.94 動脈:- 静脈:10.40 リンパ節:5.67 末梢血:- 脾臓:7.17 胸腺:- 骨髄:7 脂肪:9.94 骨:8.36 皮膚:8.71
CAGE 大脳:5.23 小脳:- 脳幹:5.52 脳梁:- 松果体:- 末梢神経:- 脊柱:5.77 網膜:- 目:- 動脈:4.95 静脈:- リンパ節:2.77 末梢血:- 脾臓:3.74 胸腺:2.22 骨髄:- 脂肪:- 骨:3.75 皮膚:5.68
RNA-seq 大脳:9.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:55.20 前立腺:30.90 卵巣:126.40 精巣:147.80 心臓:223.20 骨格筋:35.50 食道:- 胃:98.20 腸:- 結腸:17.60     肝臓:-        肺:150.60    膀胱:- 腎臓:120.90 下垂体:400.40 甲状腺:112.50 副腎:424.40 膵臓:9.40 乳腺:94.70 唾液腺:-
GeneChip 子宮:8.32 胎盤:9.96 前立腺:5 卵巣:11.41 精巣:7.10 心臓:10.47 骨格筋:6.40 食道:- 胃:8.62 腸:6.75 結腸:- 肝臓:5.30 肺:8.04 膀胱:6.39 腎臓:5.07 下垂体:6.43 甲状腺:- 副腎:6.94 膵臓:6.36 乳腺:7.85 唾液腺:6.28
CAGE 子宮:4.82 胎盤:6.06 前立腺:2.06 卵巣:6.61 精巣:3.16 心臓:- 骨格筋:- 食道:- 胃:4.94 腸:2.93 結腸:3.33     肝臓:2.41    肺:4.04 膀胱:3.01 腎臓:- 下垂体:3.42 甲状腺:- 副腎:3.98 膵臓:2.33 乳腺:3.49 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.89 食道:- 胃:- 腸:- 結腸:-     肝臓:2.90        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010288
Gene ID 14609
Unigene ID Mm.378921
Probe set ID 1415801_at  [Mouse430_2]
Ensembl ID ENSMUSG00000050953

オーソログ対応遺伝子

ヒト[1]  NM_000165
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007512  adult heart development
GO:0006915  apoptosis
GO:0015867  ATP transport
GO:0003294  atrial ventricular junction remodeling
GO:0048514  blood vessel morphogenesis
GO:0007154  cell communication
GO:0010643  cell communication by chemical coupling
GO:0010644  cell communication by electrical coupling
GO:0045216  cell-cell junction organization
GO:0007267  cell-cell signaling
GO:0002544  chronic inflammatory response
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0042733  embryonic digit morphogenesis
GO:0035050  embryonic heart tube development
GO:0003347  epicardial cell to mesenchymal cell transition
GO:0002070  epithelial cell maturation
GO:0090162  establishment of epithelial cell polarity
GO:0007507  heart development
GO:0001947  heart looping
GO:0001701  in utero embryonic development
GO:0002088  lens development in camera-type eye
GO:0060156  milk ejection
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0010629  negative regulation of gene expression
GO:0001764  neuron migration
GO:0048812  neuron projection morphogenesis
GO:0001649  osteoblast differentiation
GO:0010652  positive regulation of cell communication by chemical coupling
GO:0010628  positive regulation of gene expression
GO:0003104  positive regulation of glomerular filtration
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045732  positive regulation of protein catabolic process
GO:0045844  positive regulation of striated muscle tissue development
GO:0045907  positive regulation of vasoconstriction
GO:0045909  positive regulation of vasodilation
GO:0051259  protein oligomerization
GO:0060371  regulation of atrial cardiomyocyte membrane depolarization
GO:0060312  regulation of blood vessel remodeling
GO:0030500  regulation of bone mineralization
GO:0046850  regulation of bone remodeling
GO:0051924  regulation of calcium ion transport
GO:0008016  regulation of heart contraction
GO:0060373  regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307  regulation of ventricular cardiomyocyte membrane repolarization
GO:0009268  response to pH
GO:0007165  signal transduction
GO:0043403  skeletal muscle tissue regeneration
GO:0055085  transmembrane transport
GO:0010232  vascular transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0030054  cell junction
GO:0005911  cell-cell junction
GO:0005922  connexon complex
GO:0043292  contractile fiber
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005769  early endosome
GO:0005768  endosome
GO:0005916  fascia adherens
GO:0005921  gap junction
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0014704  intercalated disc
GO:0005882  intermediate filament
GO:0005770  late endosome
GO:0016328  lateral plasma membrane
GO:0005764  lysosome
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005741  mitochondrial outer membrane
GO:0005771  multivesicular body
GO:0005886  plasma membrane

Molecular Function

GO:0048487  beta-tubulin binding
GO:0071253  connexin binding
GO:0005243  gap junction channel activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0005102  receptor binding
GO:0017124  SH3 domain binding
GO:0004871  signal transducer activity
GO:0022857  transmembrane transporter activity