glutamate receptor, ionotropic, NMDA2A (epsilon 1)

詳細情報を見る

同義遺伝子名

GluRepsilon1, NMDAR2A, glutamate receptor, ionotropic, NMDA2A (epsilon 1), Grin2a, N-methyl D-aspartate receptor subtype 2A, NR2A

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:22.60 小脳:55.30 脳幹:31.80 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:38 動脈:84.40 静脈:- リンパ節:32.40 末梢血:115 脾臓:- 胸腺:59.30 骨髄:- 脂肪:- 骨:12.50 皮膚:23.80
GeneChip 大脳:4.64 小脳:4.54 脳幹:- 脳梁:- 松果体:- 末梢神経:3.93 脊柱:4.16 網膜:4.01 目:4.07 動脈:- 静脈:3.75 リンパ節:3.89 末梢血:- 脾臓:3.96 胸腺:- 骨髄:3.77 脂肪:3.87 骨:3.89 皮膚:3.89
CAGE 大脳:4.50 小脳:- 脳幹:3.17 脳梁:- 松果体:- 末梢神経:- 脊柱:2.96 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0.63 皮膚:0
RNA-seq 大脳:2.03 小脳:2.03 脳幹:2.03 脳梁:2.03 松果体:2.03 末梢神経:2.03 脊柱:2.03 網膜:2.03 目:2.03 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:92.60 卵巣:11.50 精巣:- 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:30.10    膀胱:66.20 腎臓:- 下垂体:38.80 甲状腺:- 副腎:- 膵臓:37.50 乳腺:19.60 唾液腺:54
GeneChip 子宮:3.67 胎盤:4.08 前立腺:3.82 卵巣:3.67 精巣:4.29 心臓:4.16 骨格筋:3.95 食道:- 胃:3.79 腸:3.82 結腸:- 肝臓:4.31 肺:3.74 膀胱:3.72 腎臓:3.92 下垂体:3.94 甲状腺:- 副腎:3.96 膵臓:4.19 乳腺:3.85 唾液腺:3.99
CAGE 子宮:0 胎盤:0 前立腺:0.20 卵巣:0.13 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:0 膀胱:0 腎臓:- 下垂体:0.99 甲状腺:- 副腎:0.26 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008170
Gene ID 14811
Unigene ID Mm.295306
Probe set ID 1421616_at  [Mouse430_2]
Ensembl ID ENSMUSG00000059003

オーソログ対応遺伝子

ヒト[3]  NM_000833, NM_001134407, NM_001134408
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1374164
1377365
1385220
1493227
7510577
7518474
7518475
7723623
7816096
7904155
7929101
7929904
8015722
8036251
8061049
8180471
8267632
8595214
8601798
8699248
8742049
8756432
8840015
8965641
8987814
8996814
9003035
9004271
9011744
9113374
9147327
9427357
9458051
9512392
9579645
9647694
9712642
9718984
9768843
9822733
9892651
10349636
10479680
10694228
10727704
10767319
10771345
10862698
10972963
10998114
11042159
11076861
11160454
11217851
11259776
11285019
11422443
11487658
11488959
11530236
11719203
11897109
11920728
12008020
12103442
12147342
12191494
12191501
12391294
12427824
12466851
12467588
12552130
12588844
12591944
12676993
12735629
12754515
12767483
12878694
12890763
12941447
14534245
14602821
14622577
14645471
14750973
14985927
15066262
15317856
15385364
15519237
15537884
15590926
15663482
15715677
15716419
15731593
15748150
15813953
16033900
16045501
16141072
16141073
16157280
16162920
16189474
16190898
16207881
16221859
16332682
16356642
16438943
16452087
16554481
16602821
16710293
16793155
16814779
16835771
16885526
16899073
16901514
16944113
16987237
17018287
17114649
17229826
17296552
17329427
17350656
17803966
17804581
17879376
17898222
17901118
18054859
18077676
18082335
18197970
18216203
18230672
18372311
18385321
18423999
18540994
18565157
18603407
18685090
18773961
18851757
18945678
19208628
19240213
19243221
19276107
19298817
19332541
19439493
19455133
19474217
19605640
19806658
19834457
19955431
20418887
20661302
20696923
20732897
20828614
20831617
20921396
20923697
20936660
21060893
21106831
21185357
21190942
21267068
21297630
21503117
21521618
21558424
21664258
21677750
21725314
21832195
21943605
21945132
21955919
22187052
22306487
22334046
22351628
22396402
22526419
22565825
22723691
22855824
22933778
22956849
23201971
23259945
23557693
23618906
23760271
23871830
23892010
23964123
24096375
24101472
24491550

遺伝子オントロジー  (GO ID)

Biological Process

GO:0070588  calcium ion transmembrane transport
GO:0006816  calcium ion transport
GO:0071230  cellular response to amino acid stimulus
GO:0071294  cellular response to zinc ion
GO:0050966  detection of mechanical stimulus involved in sensory perception of pain
GO:0033058  directional locomotion
GO:0042417  dopamine metabolic process
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0007612  learning
GO:0007611  learning or memory
GO:0040011  locomotion
GO:0007626  locomotory behavior
GO:0007613  memory
GO:0042177  negative regulation of protein catabolic process
GO:0022008  neurogenesis
GO:0043065  positive regulation of apoptosis
GO:0010942  positive regulation of cell death
GO:0008104  protein localization
GO:0051262  protein tetramerization
GO:0001508  regulation of action potential
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0042391  regulation of membrane potential
GO:0060078  regulation of postsynaptic membrane potential
GO:0051930  regulation of sensory perception of pain
GO:0048167  regulation of synaptic plasticity
GO:0050804  regulation of synaptic transmission
GO:0001975  response to amphetamine
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0009611  response to wounding
GO:0048511  rhythmic process
GO:0019233  sensory perception of pain
GO:0042428  serotonin metabolic process
GO:0030431  sleep
GO:0001964  startle response
GO:0007268  synaptic transmission
GO:0006810  transport
GO:0008542  visual learning

Cellular Component

GO:0030054  cell junction
GO:0009986  cell surface
GO:0043197  dendritic spine
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0017146  N-methyl-D-aspartate selective glutamate receptor complex
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane
GO:0045202  synapse
GO:0008021  synaptic vesicle
GO:0043195  terminal button

Molecular Function

GO:0051117  ATPase binding
GO:0005262  calcium channel activity
GO:0005261  cation channel activity
GO:0050839  cell adhesion molecule binding
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0016595  glutamate binding
GO:0035254  glutamate receptor binding
GO:0005216  ion channel activity
GO:0004970  ionotropic glutamate receptor activity
GO:0046872  metal ion binding
GO:0004972  N-methyl-D-aspartate selective glutamate receptor activity
GO:0042165  neurotransmitter binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0019901  protein kinase binding
GO:0004872  receptor activity
GO:0005215  transporter activity
GO:0022843  voltage-gated cation channel activity
GO:0008270  zinc ion binding