histone deacetylase 2

同義遺伝子名

HD2, Hdac2, histone deacetylase 2, D10Wsu179e, Yy1bp, YAF1, YY1 transcription factor-binding protein, Histone deacetylase 2, mRPD3

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:36.50

小脳:-

脳幹:31.80

脳梁:-

松果体:-

末梢神経:133.80

脊柱:-

網膜:64.30

目:22.80

動脈:-

静脈:-

リンパ節:-

末梢血:86.30

脾臓:13.20

胸腺:39.50

骨髄:38.50

脂肪:-

骨:12.50

皮膚:31.70

GeneChip

大脳:7.97

小脳:7.05

脳幹:-

脳梁:-

松果体:-

末梢神経:8.47

脊柱:7.56

網膜:6.90

目:6.24

動脈:-

静脈:8.37

リンパ節:7.75

末梢血:-

脾臓:7.47

胸腺:-

骨髄:8.16

脂肪:7.40

骨:8.02

皮膚:7.94

CAGE

大脳:4.34

小脳:-

脳幹:4.15

脳梁:-

松果体:-

末梢神経:-

脊柱:4.25

網膜:-

目:-

動脈:4.26

静脈:-

リンパ節:4.10

末梢血:-

脾臓:4.05

胸腺:4.68

骨髄:-

脂肪:-

骨:3.91

皮膚:4.20

RNA-seq

大脳:8.24

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:130.90

胎盤:-

前立腺:-

卵巣:34.50

精巣:14.80

心臓:37.20

骨格筋:35.50

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:30.10

膀胱:-

腎臓:8.10

下垂体:64.60

甲状腺:-

副腎:-

膵臓:9.40

乳腺:39.20

唾液腺:-

GeneChip

子宮:8.75

胎盤:6.40

前立腺:7.64

卵巣:8.85

精巣:7.65

心臓:6.89

骨格筋:8.49

食道:-

胃:7.38

腸:7.40

結腸:-

肝臓:6.57

肺:7.87

膀胱:7.49

腎臓:6.83

下垂体:7.98

甲状腺:-

副腎:8.17

膵臓:6.79

乳腺:7.60

唾液腺:7.11

CAGE

子宮:4.69

胎盤:3.58

前立腺:3.80

卵巣:4.48

精巣:4.39

心臓:-

骨格筋:-

食道:-

胃:3.94

腸:3.80

結腸:3.62

肝臓:3.70

肺:4.10

膀胱:3.89

腎臓:-

下垂体:4.10

甲状腺:-

副腎:4.13

膵臓:3.41

乳腺:3.67

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:9.00

食道:-

胃:-

腸:-

結腸:-

肝臓:4.84

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008229
Gene ID	15182
Unigene ID	Mm.19806
Probe set ID	1449080_at [Mouse430_2]
Ensembl ID	ENSMUSG00000019777

オーソログ対応遺伝子

ヒト[1]	NM_001527
ラット[1]	NM_053447

染色体

遺伝子ファミリー (Interpro ID)

IPR003084	Histone deacetylase
IPR000286	Histone deacetylase superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0055013	cardiac muscle cell development
GO:0016568	chromatin modification
GO:0016358	dendrite development
GO:0042733	embryonic digit morphogenesis
GO:0009913	epidermal cell differentiation
GO:0060789	hair follicle placode formation
GO:0021766	hippocampus development
GO:0016575	histone deacetylation
GO:0070932	histone H3 deacetylation
GO:0070933	histone H4 deacetylation
GO:0006344	maintenance of chromatin silencing
GO:0043066	negative regulation of apoptosis
GO:0060044	negative regulation of cardiac muscle cell proliferation
GO:0010977	negative regulation of neuron projection development
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0030182	neuron differentiation
GO:0042475	odontogenesis of dentine-containing tooth
GO:0008284	positive regulation of cell proliferation
GO:0048714	positive regulation of oligodendrocyte differentiation
GO:0045862	positive regulation of proteolysis
GO:0010870	positive regulation of receptor biosynthetic process
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006476	protein amino acid deacetylation
GO:0051896	regulation of protein kinase B signaling cascade
GO:0060297	regulation of sarcomere organization
GO:0006355	regulation of transcription, DNA-dependent
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0000785	chromatin
GO:0005737	cytoplasm
GO:0035098	ESC/E(Z) complex
GO:0000792	heterochromatin
GO:0000118	histone deacetylase complex
GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0016581	NuRD complex
GO:0005657	replication fork
GO:0016580	Sin3 complex
GO:0005667	transcription factor complex
GO:0017053	transcriptional repressor complex

Molecular Function

GO:0003682	chromatin binding
GO:0031490	chromatin DNA binding
GO:0019899	enzyme binding
GO:0031072	heat shock protein binding
GO:0004407	histone deacetylase activity
GO:0031078	histone deacetylase activity (H3-K14 specific)
GO:0034739	histone deacetylase activity (H3-K16 specific)
GO:0032129	histone deacetylase activity (H3-K9 specific)
GO:0016787	hydrolase activity
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515	protein binding
GO:0033558	protein deacetylase activity
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

histone deacetylase 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function