histone deacetylase 5

詳細情報を見る

同義遺伝子名

HD5, mKIAA0600, histone deacetylase 5, Histone deacetylase 5, mHDA1, AI426555, Histone deacetylase mHDA1, Hdac5, Hdac4

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:237.90 小脳:73.70 脳幹:127.10 脳梁:- 松果体:257.80 末梢神経:152.90 脊柱:189.10 網膜:128.60 目:190 動脈:168.80 静脈:- リンパ節:216 末梢血:43.10 脾臓:144.80 胸腺:29.60 骨髄:25.60 脂肪:- 骨:263 皮膚:174.20
GeneChip 大脳:9.38 小脳:9.21 脳幹:- 脳梁:- 松果体:- 末梢神経:7.81 脊柱:9.40 網膜:9.23 目:7.83 動脈:- 静脈:7.87 リンパ節:7.93 末梢血:- 脾臓:8.11 胸腺:- 骨髄:8.16 脂肪:8.32 骨:7.78 皮膚:8.75
CAGE 大脳:4.31 小脳:- 脳幹:4.71 脳梁:- 松果体:- 末梢神経:- 脊柱:4.56 網膜:- 目:- 動脈:3.87 静脈:- リンパ節:3.24 末梢血:- 脾臓:3.13 胸腺:3.14 骨髄:- 脂肪:- 骨:3.54 皮膚:4.30
RNA-seq 大脳:25.44 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:138.10 前立腺:30.90 卵巣:11.50 精巣:36.90 心臓:446.40 骨格筋:106.50 食道:- 胃:32.70 腸:- 結腸:35.20     肝臓:63.40        肺:80.30    膀胱:198.50 腎臓:56.40 下垂体:77.50 甲状腺:112.50 副腎:424.40 膵臓:103.20 乳腺:114.30 唾液腺:270
GeneChip 子宮:8.87 胎盤:7.64 前立腺:8.04 卵巣:8.54 精巣:8.77 心臓:8.49 骨格筋:8.33 食道:- 胃:7.93 腸:7.57 結腸:- 肝臓:8.10 肺:8.61 膀胱:8.24 腎臓:8.04 下垂体:8.89 甲状腺:- 副腎:8.31 膵臓:8.08 乳腺:8.04 唾液腺:8.12
CAGE 子宮:3.69 胎盤:2.92 前立腺:3.29 卵巣:3.65 精巣:2.89 心臓:- 骨格筋:- 食道:- 胃:3.13 腸:2.69 結腸:3.21     肝臓:3.09    肺:3.91 膀胱:3.87 腎臓:- 下垂体:3.95 甲状腺:- 副腎:3.79 膵臓:3.80 乳腺:3.23 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.35 食道:- 胃:- 腸:- 結腸:-     肝臓:5.20        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0042113  B cell activation
GO:0030183  B cell differentiation
GO:0071498  cellular response to fluid shear stress
GO:0016568  chromatin modification
GO:0007507  heart development
GO:0016575  histone deacetylation
GO:0006954  inflammatory response
GO:0033555  multicellular organismal response to stress
GO:0090051  negative regulation of cell migration involved in sprouting angiogenesis
GO:0010832  negative regulation of myotube differentiation
GO:0045668  negative regulation of osteoblast differentiation
GO:0045843  negative regulation of striated muscle tissue development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007399  nervous system development
GO:0002076  osteoblast development
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010830  regulation of myotube differentiation
GO:0043393  regulation of protein binding
GO:0048742  regulation of skeletal muscle fiber development
GO:0051153  regulation of striated muscle cell differentiation
GO:0006355  regulation of transcription, DNA-dependent
GO:0042220  response to cocaine
GO:0042493  response to drug
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0000118  histone deacetylase complex
GO:0016604  nuclear body
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0004407  histone deacetylase activity
GO:0031078  histone deacetylase activity (H3-K14 specific)
GO:0034739  histone deacetylase activity (H3-K16 specific)
GO:0032129  histone deacetylase activity (H3-K9 specific)
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0005080  protein kinase C binding
GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding