hairy/enhancer-of-split related with YRPW motif 2

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同義遺伝子名

HESR-2, Hairy/enhancer-of-split related with YRPW motif 2, Hesr2, Herp, HES-related repressor protein 2, Herp1, Hairy-related transcription factor 2, CHF1, Hairy and enhancer of split-related protein 2, Hrt2, Hairy-E(spl)-related with YRPW motif 2, Chf1, hairy/enhancer-of-split related with YRPW motif 2, Hey2, hesr2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:114.70 脊柱:47.30 網膜:64.30 目:- 動脈:168.80 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:19.80 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.27 小脳:3.93 脳幹:- 脳梁:- 松果体:- 末梢神経:6.90 脊柱:4.45 網膜:4.78 目:3.90 動脈:- 静脈:5.77 リンパ節:3.76 末梢血:- 脾臓:3.95 胸腺:- 骨髄:3.57 脂肪:3.74 骨:3.68 皮膚:3.68
CAGE 大脳:1.49 小脳:- 脳幹:1.52 脳梁:- 松果体:- 末梢神経:- 脊柱:2.38 網膜:- 目:- 動脈:2.72 静脈:- リンパ節:0 末梢血:- 脾臓:0.41 胸腺:0.49 骨髄:- 脂肪:- 骨:0 皮膚:0.60
RNA-seq 大脳:1.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:14.80 心臓:55.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:42.40 唾液腺:-
GeneChip 子宮:3.96 胎盤:3.61 前立腺:3.66 卵巣:5.20 精巣:3.80 心臓:4.11 骨格筋:3.54 食道:- 胃:3.65 腸:3.53 結腸:- 肝臓:3.69 肺:3.96 膀胱:3.59 腎臓:3.75 下垂体:4.49 甲状腺:- 副腎:3.91 膵臓:3.72 乳腺:3.54 唾液腺:3.90
CAGE 子宮:0.65 胎盤:0.41 前立腺:0.74 卵巣:2.30 精巣:0.75 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:0.84 結腸:0.41     肝臓:0.26    肺:1.28 膀胱:0.77 腎臓:- 下垂体:1.63 甲状腺:- 副腎:0.71 膵臓:0 乳腺:0.22 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.01 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_013904
Gene ID 15214
Unigene ID Mm.103573
Probe set ID 1418106_at  [Mouse430_2]
Ensembl ID ENSMUSG00000019789

オーソログ対応遺伝子

ヒト[1]  NM_012259
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009948  anterior/posterior axis specification
GO:0060842  arterial endothelial cell differentiation
GO:0060840  artery development
GO:0060413  atrial septum morphogenesis
GO:0003171  atrioventricular valve development
GO:0001568  blood vessel development
GO:0060317  cardiac epithelial to mesenchymal transition
GO:0003214  cardiac left ventricle morphogenesis
GO:0003300  cardiac muscle hypertrophy
GO:0014898  cardiac muscle hypertrophy in response to stress
GO:0003215  cardiac right ventricle morphogenesis
GO:0060411  cardiac septum morphogenesis
GO:0060948  cardiac vascular smooth muscle cell development
GO:0003208  cardiac ventricle morphogenesis
GO:0045165  cell fate commitment
GO:0090102  cochlea development
GO:0060977  coronary vasculature morphogenesis
GO:0003199  endocardial cushion to mesenchymal transition involved in valve formation
GO:0060347  heart trabecula formation
GO:0060716  labyrinthine layer blood vessel development
GO:0014031  mesenchymal cell development
GO:0007275  multicellular organismal development
GO:0003150  muscular septum morphogenesis
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0010629  negative regulation of gene expression
GO:0045746  negative regulation of Notch signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0060633  negative regulation of transcription initiation from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007219  Notch signaling pathway
GO:0003151  outflow tract morphogenesis
GO:0007389  pattern specification process
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0010460  positive regulation of heart rate
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0065004  protein-DNA complex assembly
GO:0003184  pulmonary valve morphogenesis
GO:0045607  regulation of auditory receptor cell differentiation
GO:0010468  regulation of gene expression
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent
GO:0003195  tricuspid valve formation
GO:0003186  tricuspid valve morphogenesis
GO:0001570  vasculogenesis
GO:0055015  ventricular cardiac muscle cell development
GO:0060412  ventricular septum morphogenesis
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0016580  Sin3 complex
GO:0005667  transcription factor complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003677  DNA binding
GO:0042826  histone deacetylase binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding