hypoxia inducible factor 1, alpha subunit

 詳細情報を見る

同義遺伝子名

AA959795, hypoxia inducible factor 1, alpha subunit, HIF1 alpha, HIF-1alpha, ARNT-interacting protein, MOP1, Hypoxia-inducible factor 1 alpha, Hif1a, HIF-1 alpha

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:33 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:47.30 網膜:64.30 目:60.80 動脈:- 静脈:- リンパ節:10.80 末梢血:14.40 脾臓:52.70 胸腺:49.40 骨髄:76.90 脂肪:- 骨:25 皮膚:15.80
GeneChip 大脳:9.90 小脳:11.02 脳幹:- 脳梁:- 松果体:- 末梢神経:10.07 脊柱:10.01 網膜:11.28 目:10.86 動脈:- 静脈:11.92 リンパ節:11.19 末梢血:- 脾臓:10.71 胸腺:- 骨髄:9.88 脂肪:10.05 骨:10.30 皮膚:11.17
CAGE 大脳:4.33 小脳:- 脳幹:4.02 脳梁:- 松果体:- 末梢神経:- 脊柱:4.25 網膜:- 目:- 動脈:4.16 静脈:- リンパ節:4.54 末梢血:- 脾臓:3.56 胸腺:4.32 骨髄:- 脂肪:- 骨:3.41 皮膚:4.42
RNA-seq 大脳:4.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:27.60 前立腺:803 卵巣:- 精巣:103.50 心臓:111.60 骨格筋:- 食道:- 胃:65.50 腸:110.90 結腸:52.90     肝臓:36.20        肺:40.20    膀胱:- 腎臓:48.40 下垂体:- 甲状腺:- 副腎:- 膵臓:103.20 乳腺:62 唾液腺:-
GeneChip 子宮:11.13 胎盤:11.28 前立腺:10.02 卵巣:11.39 精巣:8.05 心臓:9.83 骨格筋:8.85 食道:- 胃:10.01 腸:10.28 結腸:- 肝臓:9.36 肺:9.97 膀胱:11.02 腎臓:9.83 下垂体:10.92 甲状腺:- 副腎:9.49 膵臓:9.60 乳腺:10.13 唾液腺:10.32
CAGE 子宮:4.76 胎盤:4.66 前立腺:3.61 卵巣:4.60 精巣:3.11 心臓:- 骨格筋:- 食道:- 胃:3.89 腸:4.56 結腸:3.99     肝臓:3.84    肺:3.89 膀胱:4.43 腎臓:- 下垂体:4.34 甲状腺:- 副腎:3.71 膵臓:3.36 乳腺:4.27 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.14 食道:- 胃:- 腸:- 結腸:-     肝臓:4.12        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_010431
Gene ID 15251
Unigene ID Mm.387909
Probe set ID 1427418_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021109

オーソログ対応遺伝子

ヒト[2]  NM_001243084, NM_001530, NM_181054
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR001321  Hypoxia-inducible factor-1 alpha, PAS fold
IPR000014  PAS
IPR013655  PAS fold-3

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0019896  axon transport of mitochondrion
GO:0001922  B-1 B cell homeostasis
GO:0001568  blood vessel development
GO:0048514  blood vessel morphogenesis
GO:0003208  cardiac ventricle morphogenesis
GO:0051216  cartilage development
GO:0030154  cell differentiation
GO:0006879  cellular iron ion homeostasis
GO:0071456  cellular response to hypoxia
GO:0021987  cerebral cortex development
GO:0032963  collagen metabolic process
GO:0002248  connective tissue replacement during inflammatory response
GO:0048546  digestive tract morphogenesis
GO:0051541  elastin metabolic process
GO:0035162  embryonic hemopoiesis
GO:0001892  embryonic placenta development
GO:0001837  epithelial to mesenchymal transition
GO:0042593  glucose homeostasis
GO:0001947  heart looping
GO:0042541  hemoglobin biosynthetic process
GO:0060574  intestinal epithelial cell maturation
GO:0006089  lactate metabolic process
GO:0007595  lactation
GO:0046716  muscle homeostasis
GO:0043066  negative regulation of apoptosis
GO:0030502  negative regulation of bone mineralization
GO:0045926  negative regulation of growth
GO:0043524  negative regulation of neuron apoptosis
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0070244  negative regulation of thymocyte apoptosis
GO:0032007  negative regulation of TOR signaling pathway
GO:0045906  negative regulation of vasoconstriction
GO:0001755  neural crest cell migration
GO:0021502  neural fold elevation formation
GO:0003151  outflow tract morphogenesis
GO:0032364  oxygen homeostasis
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0010634  positive regulation of epithelial cell migration
GO:0045648  positive regulation of erythrocyte differentiation
GO:0046886  positive regulation of hormone biosynthetic process
GO:0002052  positive regulation of neuroblast proliferation
GO:0010870  positive regulation of receptor biosynthetic process
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030949  positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0050790  regulation of catalytic activity
GO:0042127  regulation of cell proliferation
GO:0010468  regulation of gene expression
GO:0006110  regulation of glycolysis
GO:0070243  regulation of thymocyte apoptosis
GO:0043619  regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0006355  regulation of transcription, DNA-dependent
GO:0032909  regulation of transforming growth factor-beta2 production
GO:0001666  response to hypoxia
GO:0014850  response to muscle activity
GO:0007165  signal transduction
GO:0006351  transcription, DNA-dependent
GO:0010573  vascular endothelial growth factor production
GO:0001944  vasculature development
GO:0008542  visual learning

Cellular Component

GO:0005737  cytoplasm
GO:0031514  motile secondary cilium
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0019899  enzyme binding
GO:0035035  histone acetyltransferase binding
GO:0042826  histone deacetylase binding
GO:0051879  Hsp90 protein binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0019901  protein kinase binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0004871  signal transducer activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0031625  ubiquitin protein ligase binding