high mobility group box 1

詳細情報を見る

同義遺伝子名

HMG-1, MGC117896, Hmg-1, High mobility group protein B1, MGC103168, high mobility group box 1, Hmg1, Hmgb1, MGC117897, MGC103169, High mobility group protein 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:72.90 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:47.30 網膜:321.40 目:159.60 動脈:- 静脈:- リンパ節:- 末梢血:57.50 脾臓:- 胸腺:138.30 骨髄:320.50 脂肪:- 骨:200.40 皮膚:31.70
GeneChip 大脳:6.74 小脳:6.40 脳幹:- 脳梁:- 松果体:- 末梢神経:6.55 脊柱:6.35 網膜:5.38 目:5.58 動脈:- 静脈:7.78 リンパ節:8.26 末梢血:- 脾臓:7.73 胸腺:- 骨髄:8.78 脂肪:7.24 骨:8.50 皮膚:7.65
CAGE 大脳:1.53 小脳:- 脳幹:1.43 脳梁:- 松果体:- 末梢神経:- 脊柱:1.63 網膜:- 目:- 動脈:2.66 静脈:- リンパ節:2.26 末梢血:- 脾臓:1.12 胸腺:3.13 骨髄:- 脂肪:- 骨:0 皮膚:2.43
RNA-seq 大脳:20.25 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:261.70 胎盤:69 前立腺:525 卵巣:23 精巣:29.60 心臓:18.60 骨格筋:35.50 食道:- 胃:32.70 腸:37 結腸:70.50     肝臓:54.30        肺:220.90    膀胱:- 腎臓:72.50 下垂体:116.30 甲状腺:224.90 副腎:- 膵臓:178.30 乳腺:137.10 唾液腺:108
GeneChip 子宮:7.78 胎盤:7.38 前立腺:7.63 卵巣:8.13 精巣:6.38 心臓:6.06 骨格筋:7.98 食道:- 胃:7.08 腸:7.26 結腸:- 肝臓:6.75 肺:7.66 膀胱:7.42 腎臓:6.82 下垂体:6.65 甲状腺:- 副腎:6.89 膵臓:6.08 乳腺:7.68 唾液腺:6.25
CAGE 子宮:2.10 胎盤:2.93 前立腺:1.65 卵巣:1.60 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:1.75 腸:0 結腸:0.93     肝臓:2.82    肺:2.21 膀胱:2.27 腎臓:- 下垂体:2.06 甲状腺:- 副腎:2.39 膵臓:0.84 乳腺:1.43 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:15.41 食道:- 胃:- 腸:- 結腸:-     肝臓:30.24        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010439
Gene ID 15289
Unigene ID Mm.313345
Probe set ID 1448235_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000066551

オーソログ対応遺伝子

ヒト[9]  NM_002128
ラット[9]  NM_002128

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1630928
7607539
7635200
7741753
7784217
7961836
8180479
8268661
8535062
8599938
8661151
9016958
9047378
9598312
9767109
10349636
10391216
10922068
10962007
10978508
11042159
11076861
11217851
11262228
11404013
11748221
11964153
12040188
12126646
12198705
12429734
12466851
12477932
12488489
12604365
12609598
12887690
12904583
12930754
14532127
14571134
14660645
14744997
15140875
15162419
15226823
15272298
15331624
15488733
15489334
15618518
15640285
15649368
15747579
15782199
15795240
15808513
15834309
15944249
16040616
16141072
16141073
16242306
16282196
16365390
16407300
16419037
16919269
16920974
16935945
16940333
16980512
17062605
17114460
17135572
17203009
17268551
17290427
17331117
17406091
17417641
17430886
17475879
17475888
17522814
17548469
17548579
17599806
17609113
17626148
17652366
17666052
17803946
17872450
17984303
18000511
18031817
18056081
18173740
18179697
18197146
18239618
18287559
18302500
18411294
18441281
18554416
18558628
18574060
18582368
18599803
18606700
18631454
18650382
18665013
18687905
18714026
18762169
18798064
18799693
18802105
18973680
19064698
19097991
19109190
19139395
19141186
19197130
19201901
19208562
19209790
19212652
19218854
19360320
19366789
19379700
19380828
19401391
19414537
19435426
19454652
19487305
19492424
19494177
19587006
19679874
19741146
19800306
19890330
20007974
20014975
20028656
20059953
20124731
20231695
20231821
20412781
20418360
20671243
20682624
20700129
20703492
20709956
20714327
20802146
20810986
20826760
20847143
20855247
20856174
20932939
20935509
20936717
20937823
21093407
21113057
21186276
21248133
21294652
21296590
21300822
21319304
21372296
21384471
21389242
21395369
21419643
21431162
21457762
21464317
21488218
21525287
21610098
21641551
21642503
21644033
21660935
21666956
21677750
21691146
21705688
21738444
21809356
21828158
21828285
21832986
21884699
21921023
21928275
21944908
21957148
21971692
21990362
22068051
22189943
22204001
22234969
22275109
22314397
22328527
22370717
22396017
22398161
22430509
22459482
22527657
22529378
22634181
22634723
22759395
22772444
22801494
22821628
22841886
22842346
22869893
22890140
22896901
22909167
22922889
22962600
23040637
23063543
23087050
23148306
23195496
23201852
23288170
23303669
23316068
23325855
23331758
23407880
23438257
23449592
23508573
23514872
23518713
23539679
23552724
23565059
23607598
23623189
23649808
23665500
23677049
23707808
23708738
23722163
23770722
23782844
23831508
23865790
23866790
23899512
23942756
23948063
24005720
24089009
24162463
24257755
24302768
24325600
24350616
24361123
24374967
24375466
24469805
24474694
24612327
24717031
24752445

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006288  base-excision repair, DNA ligation
GO:0032392  DNA geometric change
GO:0001654  eye development
GO:0050930  induction of positive chemotaxis
GO:0030324  lung development
GO:0017055  negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0030335  positive regulation of cell migration
GO:0043388  positive regulation of DNA binding
GO:0045819  positive regulation of glycogen catabolic process
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045931  positive regulation of mitotic cell cycle
GO:0045639  positive regulation of myeloid cell differentiation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0051384  response to glucocorticoid stimulus
GO:0033151  V(D)J recombination

Cellular Component

GO:0009986  cell surface
GO:0000793  condensed chromosome
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003681  bent DNA binding
GO:0010858  calcium-dependent protein kinase regulator activity
GO:0000402  crossed form four-way junction DNA binding
GO:0005125  cytokine activity
GO:0008301  DNA bending activity
GO:0000401  open form four-way junction DNA binding
GO:0030295  protein kinase activator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding