heme oxygenase (decycling) 1

詳細情報を見る

同義遺伝子名

heme oxygenase (decycling) 1, Hemox, Hmox1, Hmox, HO-1, heme oxygenase 1, Heme oxygenase 1, D8Wsu38e, Hsp32, HO1, P32 protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:31.30 小脳:36.80 脳幹:- 脳梁:- 松果体:257.80 末梢神経:133.80 脊柱:- 網膜:- 目:15.20 動脈:- 静脈:- リンパ節:43.20 末梢血:28.80 脾臓:- 胸腺:9.90 骨髄:1179.60 脂肪:- 骨:613.70 皮膚:95
GeneChip 大脳:5.48 小脳:5.33 脳幹:- 脳梁:- 松果体:- 末梢神経:6.55 脊柱:5.67 網膜:5.58 目:6.82 動脈:- 静脈:7.42 リンパ節:8.92 末梢血:- 脾臓:10.35 胸腺:- 骨髄:10.45 脂肪:6.56 骨:10.01 皮膚:7.55
CAGE 大脳:1.32 小脳:- 脳幹:1.81 脳梁:- 松果体:- 末梢神経:- 脊柱:2.17 網膜:- 目:- 動脈:3.24 静脈:- リンパ節:5.31 末梢血:- 脾臓:6.08 胸腺:2.38 骨髄:- 脂肪:- 骨:5.83 皮膚:4.58
RNA-seq 大脳:2.31 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:69 前立腺:- 卵巣:80.40 精巣:73.90 心臓:74.40 骨格筋:35.50 食道:- 胃:32.70 腸:- 結腸:17.60     肝臓:36.20        肺:50.20    膀胱:66.20 腎臓:64.50 下垂体:- 甲状腺:- 副腎:- 膵臓:84.40 乳腺:117.50 唾液腺:54
GeneChip 子宮:6.74 胎盤:9.57 前立腺:5.78 卵巣:6.98 精巣:6.31 心臓:6.14 骨格筋:6.16 食道:- 胃:7.76 腸:5.60 結腸:- 肝臓:6.86 肺:6.97 膀胱:6.41 腎臓:7.37 下垂体:5.78 甲状腺:- 副腎:8.71 膵臓:5.94 乳腺:6.46 唾液腺:6.80
CAGE 子宮:3.04 胎盤:5.36 前立腺:2.43 卵巣:4.10 精巣:3.13 心臓:- 骨格筋:- 食道:- 胃:4.52 腸:1.99 結腸:1.68     肝臓:4.07    肺:3.70 膀胱:2.99 腎臓:- 下垂体:2.35 甲状腺:- 副腎:5.36 膵臓:2.03 乳腺:2.96 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.66 食道:- 胃:- 腸:- 結腸:-     肝臓:5.54        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010442
Gene ID 15368
Unigene ID Mm.276389
Probe set ID 1448239_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005413

オーソログ対応遺伝子

ヒト[1]  NM_002133
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1400499
3409220
7538129
7929191
8288554
8630002
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8827514
8974842
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0008219  cell death
GO:0071243  cellular response to arsenic
GO:0071276  cellular response to cadmium ion
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0034101  erythrocyte homeostasis
GO:0002246  healing during inflammatory response
GO:0042167  heme catabolic process
GO:0042168  heme metabolic process
GO:0006788  heme oxidation
GO:0055072  iron ion homeostasis
GO:0008285  negative regulation of cell proliferation
GO:0043392  negative regulation of DNA binding
GO:0032764  negative regulation of mast cell cytokine production
GO:0043305  negative regulation of mast cell degranulation
GO:0010656  negative regulation of muscle cell apoptosis
GO:0043524  negative regulation of neuron apoptosis
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0043433  negative regulation of transcription factor activity
GO:0055114  oxidation reduction
GO:0045766  positive regulation of angiogenesis
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0051260  protein homooligomerization
GO:0008217  regulation of blood pressure
GO:0051090  regulation of transcription factor activity
GO:0043619  regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627  response to estrogen stimulus
GO:0042542  response to hydrogen peroxide
GO:0035094  response to nicotine
GO:0006979  response to oxidative stress
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005901  caveola
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0019899  enzyme binding
GO:0020037  heme binding
GO:0004392  heme oxygenase (decyclizing) activity
GO:0046872  metal ion binding
GO:0016491  oxidoreductase activity
GO:0004630  phospholipase D activity
GO:0042803  protein homodimerization activity
GO:0004871  signal transducer activity