hepatic nuclear factor 4, alpha

同義遺伝子名

Hnf-4, hepatic nuclear factor 4, alpha, Hnf4, Transcription factor 14, HNF-4-alpha, Tcf14, Transcription factor HNF-4, Hnf4a, Nuclear receptor 2A1, Nr2a1, HNF4 alpha, D19Mgi10, MODY1, HNF-4, Hepatocyte nuclear factor 4-alpha

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:14.40

脾臓:39.50

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:4.05

小脳:4.75

脳幹:-

脳梁:-

松果体:-

末梢神経:4.03

脊柱:4.35

網膜:4.20

目:4.34

動脈:-

静脈:4.02

リンパ節:3.79

末梢血:-

脾臓:3.95

胸腺:-

骨髄:3.79

脂肪:4.63

骨:3.93

皮膚:3.92

CAGE

大脳:0

小脳:-

脳幹:0

脳梁:-

松果体:-

末梢神経:-

脊柱:0

網膜:-

目:-

動脈:0.14

静脈:-

リンパ節:0

末梢血:-

脾臓:0

胸腺:0

骨髄:-

脂肪:-

骨:0

皮膚:0

RNA-seq

大脳:1.97

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:55.20

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:32.70

腸:295.80

結腸:246.70

肝臓:371.10

肺:-

膀胱:-

腎臓:362.70

下垂体:-

甲状腺:-

副腎:-

膵臓:56.30

乳腺:-

唾液腺:-

GeneChip

子宮:3.92

胎盤:5.13

前立腺:4.01

卵巣:3.78

精巣:4.18

心臓:4.31

骨格筋:4.64

食道:-

胃:8.70

腸:10.10

結腸:-

肝臓:10.44

肺:4.56

膀胱:3.93

腎臓:10.58

下垂体:4.12

甲状腺:-

副腎:4.12

膵臓:4.87

乳腺:4.11

唾液腺:4.31

CAGE

子宮:0

胎盤:1.63

前立腺:0

卵巣:0.13

精巣:0

心臓:-

骨格筋:-

食道:-

胃:4.50

腸:5.01

結腸:5.18

肝臓:5.24

肺:0

膀胱:0.18

腎臓:-

下垂体:0

甲状腺:-

副腎:0.37

膵臓:3.53

乳腺:0

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:46.60

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008261
Gene ID	15378
Unigene ID	Mm.202383
Probe set ID	1421983_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000017950

オーソログ対応遺伝子

ヒト[10]	NM_000457, NM_001030003, NM_001030004, NM_175914, NM_178849, NM_178850
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000003	Retinoid X receptor
IPR001723	Steroid hormone receptor
IPR003068	Transcription factor COUP
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

遺伝子オントロジー (GO ID)

Biological Process

GO:0006637	acyl-CoA metabolic process
GO:0007596	blood coagulation
GO:0030154	cell differentiation
GO:0045216	cell-cell junction organization
GO:0007164	establishment of tissue polarity
GO:0042593	glucose homeostasis
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0055088	lipid homeostasis
GO:0006629	lipid metabolic process
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0045930	negative regulation of mitotic cell cycle
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
GO:0033159	negative regulation of protein import into nucleus, translocation
GO:0043433	negative regulation of transcription factor activity
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0006591	ornithine metabolic process
GO:0055091	phospholipid homeostasis
GO:0045723	positive regulation of fatty acid biosynthetic process
GO:0045722	positive regulation of gluconeogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0010470	regulation of gastrulation
GO:0050796	regulation of insulin secretion
GO:0019216	regulation of lipid metabolic process
GO:0032534	regulation of microvillus assembly
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0009749	response to glucose stimulus
GO:0007548	sex differentiation
GO:0060395	SMAD protein signal transduction
GO:0043401	steroid hormone mediated signaling pathway
GO:0006351	transcription, DNA-dependent
GO:0070328	triglyceride homeostasis
GO:0006805	xenobiotic metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0000062	acyl-CoA binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005504	fatty acid binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0046872	metal ion binding
GO:0016290	palmitoyl-CoA hydrolase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0070491	transcription repressor binding
GO:0008270	zinc ion binding

hepatic nuclear factor 4, alpha

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function