insulin-like growth factor 2

詳細情報を見る

同義遺伝子名

Igf-II, Multiplication-stimulating polypeptide, IGF-II, M6pr, Mpr, AL033362, Peg2, Igf-2, insulin-like growth factor 2, Insulin-like growth factor II precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:64.30 小脳:- 脳幹:- 脳梁:- 松果体:1031.20 末梢神経:324.80 脊柱:- 網膜:96.40 目:220.40 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:413.30 皮膚:166.30
GeneChip 大脳:8.55 小脳:8.87 脳幹:- 脳梁:- 松果体:- 末梢神経:8.64 脊柱:8.49 網膜:8.14 目:7.33 動脈:- 静脈:14.39 リンパ節:6.01 末梢血:- 脾臓:7.36 胸腺:- 骨髄:6.01 脂肪:7.99 骨:7.43 皮膚:8.21
CAGE 大脳:4.97 小脳:- 脳幹:4.60 脳梁:- 松果体:- 末梢神経:- 脊柱:4.37 網膜:- 目:- 動脈:3.48 静脈:- リンパ節:2.11 末梢血:- 脾臓:1.52 胸腺:1.43 骨髄:- 脂肪:- 骨:1.30 皮膚:2.42
RNA-seq 大脳:9.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:479.90 胎盤:704.20 前立腺:61.80 卵巣:298.80 精巣:29.60 心臓:930.10 骨格筋:177.50 食道:- 胃:- 腸:- 結腸:17.60     肝臓:99.60        肺:40.20    膀胱:- 腎臓:32.20 下垂体:64.60 甲状腺:- 副腎:- 膵臓:272.10 乳腺:9.80 唾液腺:-
GeneChip 子宮:6.64 胎盤:13.72 前立腺:7.14 卵巣:7.08 精巣:7.44 心臓:8.75 骨格筋:8.43 食道:- 胃:7.67 腸:6.92 結腸:- 肝臓:6.44 肺:7.15 膀胱:7.79 腎臓:6.46 下垂体:7.07 甲状腺:- 副腎:7.24 膵臓:6.91 乳腺:9.28 唾液腺:10.23
CAGE 子宮:1.95 胎盤:7.50 前立腺:2.09 卵巣:2.51 精巣:1.48 心臓:- 骨格筋:- 食道:- 胃:2.73 腸:1.14 結腸:1.58     肝臓:0    肺:2.03 膀胱:3.09 腎臓:- 下垂体:2.79 甲状腺:- 副腎:2.48 膵臓:1.30 乳腺:3.18 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.04 食道:- 胃:- 腸:- 結腸:-     肝臓:0.89        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010514
Gene ID 16002
Unigene ID Mm.3862
Probe set ID 1448152_at  [Mouse430_2]
Ensembl ID ENSMUSG00000048583

オーソログ対応遺伝子

ヒト[18]  NM_000612, NM_001007139, NM_001127598
ラット[4]  NM_001190162, NM_001190163, NM_031511

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1284245
1303252
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1457378
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0031017  exocrine pancreas development
GO:0006006  glucose metabolic process
GO:0007613  memory
GO:0009887  organ morphogenesis
GO:0001503  ossification
GO:0042104  positive regulation of activated T cell proliferation
GO:0043085  positive regulation of catalytic activity
GO:0051781  positive regulation of cell division
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0046628  positive regulation of insulin receptor signaling pathway
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0090031  positive regulation of steroid hormone biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042493  response to drug
GO:0035094  response to nicotine
GO:0014070  response to organic cyclic substance
GO:0051146  striated muscle cell differentiation

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0008083  growth factor activity
GO:0005179  hormone activity
GO:0005158  insulin receptor binding
GO:0005159  insulin-like growth factor receptor binding
GO:0005515  protein binding
GO:0043539  protein serine/threonine kinase activator activity
GO:0030546  receptor activator activity