interleukin 12a

詳細情報を見る

同義遺伝子名

Ll12a, Il-12a, MGC151232, Il12a, CLMF p35, interleukin 12a, IL-12p35, IL-12A, MGC151228, Interleukin-12 alpha chain precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:57.50 脾臓:- 胸腺:29.60 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.09 小脳:4.06 脳幹:- 脳梁:- 松果体:- 末梢神経:3.97 脊柱:4.12 網膜:3.90 目:4.19 動脈:- 静脈:3.86 リンパ節:6.21 末梢血:- 脾臓:5.96 胸腺:- 骨髄:6.46 脂肪:4.09 骨:6.80 皮膚:4.32
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0.17 網膜:- 目:- 動脈:0.36 静脈:- リンパ節:2.41 末梢血:- 脾臓:1.41 胸腺:0.27 骨髄:- 脂肪:- 骨:1.84 皮膚:0
RNA-seq 大脳:1.06 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:45.30        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.96 胎盤:4.02 前立腺:4.02 卵巣:3.83 精巣:4.30 心臓:4.12 骨格筋:6.43 食道:- 胃:3.99 腸:3.99 結腸:- 肝臓:4.14 肺:4.22 膀胱:3.80 腎臓:3.89 下垂体:4.16 甲状腺:- 副腎:3.83 膵臓:4.48 乳腺:4.77 唾液腺:4.38
CAGE 子宮:0 胎盤:0 前立腺:0 卵巣:0 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:0.91 膀胱:0 腎臓:- 下垂体:0 甲状腺:- 副腎:0.14 膵臓:0 乳腺:0.12 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.12 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008351
Gene ID 16159
Unigene ID Mm.103783
Probe set ID 1425454_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027776

オーソログ対応遺伝子

ヒト[1]  NM_000882
ラット[1]  NM_053390

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1350290
7512032
7565674
7606797
7608551
7608555
7636252
7650381
7690439
7690440
7697544
7719935
7722464
7836934
7843232
7853541
7890716
7906942
7908914
7909536
7930611
7930625
7963574
8097524
8557982
8566070
8584935
8605935
8611715
8613697
8630732
8647196
8661733
8661735
8702400
8720612
8752918
8766560
8933280
8977288
8995720
9348310
9402110
9444325
9482910
9502787
9515809
9551892
9558103
9570526
9647215
9743382
9878080
9916727
9933080
9933106
10072260
10073981
10075980
10199581
10201930
10209048
10221644
10233771
10320373
10335479
10349636
10358203
10375558
10395644
10395683
10415056
10427977
10452994
10457211
10594747
10604999
10605032
10667588
10671189
10741399
10779748
11023473
11042159
11046000
11057672
11076861
11118000
11145697
11160340
11197687
11207316
11217851
11412311
11544324
11673544
11673569
11737071
11739515
11782017
11786421
11801672
11818386
11920565
11937300
11986256
12165484
12189243
12193738
12223525
12370359
12396623
12414961
12429708
12466851
12471147
12477932
12516540
12540559
12594270
12610626
12697150
12807488
12829028
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12937153
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15271961
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15307169
15368276
15457342
15474355
15489234
15539151
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15611248
15614132
15634875
15654341
15860554
15871905
15958666
16002675
16141072
16141073
16148138
16157683
16195537
16263243
16357940
16393998
16428767
16455783
16621990
16648552
16670770
16684508
16688182
16707481
16751361
16751369
16785494
16785519
16790814
16818672
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16906165
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16923792
17003484
17039570
17074851
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18033300
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18056351
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18332204
18368052
18390752
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18523296
18566398
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18570589
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18656388
18713986
18715907
18725520
18762566
18809711
18818389
18981133
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19019087
19039769
19050277
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19185846
19190335
19200759
19204111
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19304955
19342674
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19357249
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19592655
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19666528
19710462
19727119
19755980
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19830723
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19853481
19923446
19950301
20107184
20122166
20207959
20333242
20364087
20404142
20404272
20483737
20581146
20592486
20610651
20921529
20953201
20974986
21071868
21148802
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21206087
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21220560
21233255
21242294
21267068
21282337
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21531892
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21741931
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21906794
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21987662
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22792256
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22834482
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23006848
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23365459
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23630349
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23753624
23776508
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23794631
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23905994
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24040208
24055061
24142033
24155889
24224652
24227786
24367005
24434636
24532579
24646742

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0016477  cell migration
GO:0042832  defense response to protozoan
GO:0006955  immune response
GO:0032700  negative regulation of interleukin-17 production
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0045785  positive regulation of cell adhesion
GO:0032729  positive regulation of interferon-gamma production
GO:0050671  positive regulation of lymphocyte proliferation
GO:0032816  positive regulation of natural killer cell activation
GO:0045954  positive regulation of natural killer cell mediated cytotoxicity
GO:0002860  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0051135  positive regulation of NK T cell activation
GO:0034393  positive regulation of smooth muscle cell apoptosis
GO:0045582  positive regulation of T cell differentiation
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0042102  positive regulation of T cell proliferation
GO:0042520  positive regulation of tyrosine phosphorylation of Stat4 protein
GO:0032496  response to lipopolysaccharide
GO:0010224  response to UV-B

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0043514  interleukin-12 complex

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0042163  interleukin-12 beta subunit binding
GO:0005143  interleukin-12 receptor binding
GO:0045513  interleukin-27 binding
GO:0046982  protein heterodimerization activity