interleukin 18

詳細情報を見る

同義遺伝子名

Il-18, Il18, interleukin 18, Interleukin-18 precursor, IFN-gamma-inducing factor, Interferon-gamma-inducing factor, IL-18, IL-1 gamma, Igif, Interleukin-1 gamma

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:24.30 小脳:- 脳幹:- 脳梁:- 松果体:257.80 末梢神経:- 脊柱:- 網膜:- 目:15.20 動脈:- 静脈:- リンパ節:- 末梢血:43.10 脾臓:52.70 胸腺:138.30 骨髄:512.90 脂肪:638.20 骨:238 皮膚:166.30
GeneChip 大脳:9.17 小脳:7.68 脳幹:- 脳梁:- 松果体:- 末梢神経:7.50 脊柱:9.01 網膜:8.51 目:10.13 動脈:- 静脈:9.40 リンパ節:10.21 末梢血:- 脾臓:9.94 胸腺:- 骨髄:9.05 脂肪:7.40 骨:8.82 皮膚:10.77
CAGE 大脳:2.85 小脳:- 脳幹:3.35 脳梁:- 松果体:- 末梢神経:- 脊柱:3.62 網膜:- 目:- 動脈:1.65 静脈:- リンパ節:3.82 末梢血:- 脾臓:3.46 胸腺:2.07 骨髄:- 脂肪:- 骨:2.19 皮膚:3.58
RNA-seq 大脳:4.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:55.20 前立腺:1142.70 卵巣:- 精巣:110.80 心臓:74.40 骨格筋:284.10 食道:- 胃:229.10 腸:517.60 結腸:105.70     肝臓:208.20        肺:120.50    膀胱:132.40 腎臓:80.60 下垂体:51.70 甲状腺:224.90 副腎:- 膵臓:150.10 乳腺:143.70 唾液腺:-
GeneChip 子宮:7.60 胎盤:5.36 前立腺:7.20 卵巣:8.37 精巣:5.84 心臓:6.01 骨格筋:7.33 食道:- 胃:11.80 腸:10.97 結腸:- 肝臓:9.12 肺:8.81 膀胱:6.99 腎臓:6.38 下垂体:7.72 甲状腺:- 副腎:7.25 膵臓:6.57 乳腺:6.94 唾液腺:6.96
CAGE 子宮:1.75 胎盤:0.41 前立腺:1.51 卵巣:2.66 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:5.34 腸:5.20 結腸:4.60     肝臓:3.09    肺:2.85 膀胱:1.83 腎臓:- 下垂体:2.71 甲状腺:- 副腎:1.64 膵臓:0 乳腺:1.12 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.69 食道:- 胃:- 腸:- 結腸:-     肝臓:2.80        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008360
Gene ID 16173
Unigene ID Mm.141021
Probe set ID 1417932_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039217

オーソログ対応遺伝子

ヒト[1]  NM_001243211, NM_001562
ラット[2]  NM_019165, NM_001562

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7477296
8666798
8766574
8892629
8999896
9022080
9108085
9247607
9434792
9490698
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10225924
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10878369
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15489334
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15557182
15574430
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15681795
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24634489

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0071407  cellular response to organic cyclic substance
GO:0071375  cellular response to peptide hormone stimulus
GO:0050966  detection of mechanical stimulus involved in sensory perception of pain
GO:0006955  immune response
GO:0008625  induction of apoptosis via death domain receptors
GO:0006954  inflammatory response
GO:0042095  interferon-gamma biosynthetic process
GO:0042231  interleukin-13 biosynthetic process
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0000165  MAPKKK cascade
GO:0030101  natural killer cell activation
GO:0042104  positive regulation of activated T cell proliferation
GO:0032722  positive regulation of chemokine production
GO:0032967  positive regulation of collagen biosynthetic process
GO:0010628  positive regulation of gene expression
GO:0032725  positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729  positive regulation of interferon-gamma production
GO:0032740  positive regulation of interleukin-17 production
GO:0032757  positive regulation of interleukin-8 production
GO:0032819  positive regulation of natural killer cell proliferation
GO:0043525  positive regulation of neuron apoptosis
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0051142  positive regulation of NK T cell proliferation
GO:0032930  positive regulation of superoxide release
GO:0032760  positive regulation of tumor necrosis factor production
GO:0043117  positive regulation of vascular permeability
GO:0030155  regulation of cell adhesion
GO:0001666  response to hypoxia
GO:0030431  sleep
GO:0042088  T-helper 1 type immune response

Cellular Component

GO:0016324  apical plasma membrane
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity