interleukin 1 beta

詳細情報を見る

同義遺伝子名

Il-1b, IL-1 beta, IL-1beta, IL-1B, interleukin 1 beta, Il1b, Interleukin-1 beta precursor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:168.80

静脈:-

リンパ節:10.80

末梢血:43.10

脾臓:79

胸腺:-

骨髄:76.90

脂肪:-

骨:-

皮膚:15.80

GeneChip

大脳:5.46

小脳:5.61

脳幹:-

脳梁:-

松果体:-

末梢神経:5.68

脊柱:5.64

網膜:5.58

目:6.26

動脈:-

静脈:5.49

リンパ節:7.24

末梢血:-

脾臓:8.37

胸腺:-

骨髄:8.49

脂肪:5.59

骨:8.23

皮膚:5.90

CAGE

大脳:0

小脳:-

脳幹:0

脳梁:-

松果体:-

末梢神経:-

脊柱:0.55

網膜:-

目:-

動脈:1.46

静脈:-

リンパ節:4.50

末梢血:-

脾臓:3.80

胸腺:1.43

骨髄:-

脂肪:-

骨:3.10

皮膚:1.78

RNA-seq

大脳:0.69

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:71

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:9.80

唾液腺:-

GeneChip

子宮:5.77

胎盤:5.74

前立腺:5.28

卵巣:5.33

精巣:5.93

心臓:6.26

骨格筋:5.48

食道:-

胃:5.87

腸:5.80

結腸:-

肝臓:6.24

肺:7.30

膀胱:5.73

腎臓:5.90

下垂体:5.66

甲状腺:-

副腎:5.54

膵臓:5.82

乳腺:5.81

唾液腺:5.67

CAGE

子宮:2.12

胎盤:0.84

前立腺:0

卵巣:0.82

精巣:0

心臓:-

骨格筋:-

食道:-

胃:1.57

腸:0.42

結腸:1.85

肝臓:1.98

肺:4.16

膀胱:0.57

腎臓:-

下垂体:1.56

甲状腺:-

副腎:1.64

膵臓:0.84

乳腺:1.47

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:0.60

食道:-

胃:-

腸:-

結腸:-

肝臓:1.08

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008361
Gene ID	16176
Unigene ID	Mm.222830
Probe set ID	1449399_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027398

オーソログ対応遺伝子

ヒト[2]	NM_000576
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR008996	Cytokine, IL-1-like
IPR002348	Interleukin 1/heparin-binding growth factor
IPR000975	Interleukin-1
IPR003294	Interleukin-1, alpha/beta
IPR003296	Interleukin-1, beta IL1B

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0007568	aging
GO:0071407	cellular response to organic cyclic substance
GO:0071310	cellular response to organic substance
GO:0019221	cytokine-mediated signaling pathway
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0001660	fever
GO:0035234	germ cell programmed cell death
GO:0030213	hyaluronan biosynthetic process
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0032611	interleukin-1 beta production
GO:0050900	leukocyte migration
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0000165	MAPKKK cascade
GO:0007613	memory
GO:0070487	monocyte aggregation
GO:0070164	negative regulation of adiponectin secretion
GO:0008285	negative regulation of cell proliferation
GO:0010629	negative regulation of gene expression
GO:0010829	negative regulation of glucose transport
GO:0014050	negative regulation of glutamate secretion
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0050995	negative regulation of lipid catabolic process
GO:0045833	negative regulation of lipid metabolic process
GO:0043407	negative regulation of MAP kinase activity
GO:0050768	negative regulation of neurogenesis
GO:0045665	negative regulation of neuron differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0030593	neutrophil chemotaxis
GO:0045766	positive regulation of angiogenesis
GO:0043065	positive regulation of apoptosis
GO:0048711	positive regulation of astrocyte differentiation
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity
GO:0010942	positive regulation of cell death
GO:0051781	positive regulation of cell division
GO:0045080	positive regulation of chemokine biosynthetic process
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0031622	positive regulation of fever
GO:0010628	positive regulation of gene expression
GO:0045687	positive regulation of glial cell differentiation
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0034116	positive regulation of heterotypic cell-cell adhesion
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032729	positive regulation of interferon-gamma production
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0045410	positive regulation of interleukin-6 biosynthetic process
GO:0032755	positive regulation of interleukin-6 production
GO:0032757	positive regulation of interleukin-8 production
GO:0046330	positive regulation of JNK cascade
GO:0043507	positive regulation of JUN kinase activity
GO:0050996	positive regulation of lipid catabolic process
GO:0051044	positive regulation of membrane protein ectodomain proteolysis
GO:0045840	positive regulation of mitosis
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0032308	positive regulation of prostaglandin secretion
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0042102	positive regulation of T cell proliferation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0043491	protein kinase B signaling cascade
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050796	regulation of insulin secretion
GO:0033198	response to ATP
GO:0009743	response to carbohydrate stimulus
GO:0032496	response to lipopolysaccharide
GO:0030730	sequestering of triglyceride
GO:0035176	social behavior

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0030141	secretory granule
GO:0031982	vesicle

Molecular Function

GO:0005125	cytokine activity
GO:0005149	interleukin-1 receptor binding
GO:0019904	protein domain specific binding

interleukin 1 beta

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function