interleukin-1 receptor-associated kinase 1

同義遺伝子名

IRAK, Plpk, Interleukin-1 receptor-associated kinase 1, interleukin-1 receptor-associated kinase 1, mPLK, Il1rak, IRAK-1, Pelle-like protein kinase, Irak1, AA408924

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:81.60

小脳:55.30

脳幹:95.30

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:96.40

目:83.60

動脈:84.40

静脈:-

リンパ節:21.60

末梢血:86.30

脾臓:65.80

胸腺:128.40

骨髄:64.10

脂肪:425.40

骨:75.10

皮膚:126.70

GeneChip

大脳:5.73

小脳:5.50

脳幹:-

脳梁:-

松果体:-

末梢神経:5.76

脊柱:5.59

網膜:6.71

目:7.23

動脈:-

静脈:6.43

リンパ節:7.21

末梢血:-

脾臓:6.68

胸腺:-

骨髄:6.70

脂肪:7.05

骨:6.53

皮膚:6.69

CAGE

大脳:2.98

小脳:-

脳幹:3.07

脳梁:-

松果体:-

末梢神経:-

脊柱:3.03

網膜:-

目:-

動脈:4.00

静脈:-

リンパ節:4.23

末梢血:-

脾臓:3.71

胸腺:3.02

骨髄:-

脂肪:-

骨:3.79

皮膚:3.65

RNA-seq

大脳:3.14

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:174.50

胎盤:13.80

前立腺:30.90

卵巣:34.50

精巣:29.60

心臓:74.40

骨格筋:71

食道:-

胃:32.70

腸:-

結腸:70.50

肝臓:72.40

肺:210.90

膀胱:132.40

腎臓:72.50

下垂体:64.60

甲状腺:-

副腎:1697.80

膵臓:131.40

乳腺:140.40

唾液腺:162

GeneChip

子宮:7.03

胎盤:6.29

前立腺:7.84

卵巣:7.02

精巣:5.17

心臓:6.60

骨格筋:6.45

食道:-

胃:6.39

腸:6.26

結腸:-

肝臓:6.79

肺:6.46

膀胱:6.57

腎臓:6.34

下垂体:7.67

甲状腺:-

副腎:7.76

膵臓:8.66

乳腺:7

唾液腺:8.64

CAGE

子宮:3.92

胎盤:3.36

前立腺:4.19

卵巣:3.90

精巣:1.34

心臓:-

骨格筋:-

食道:-

胃:3.87

腸:3.28

結腸:3.30

肝臓:3.66

肺:3.75

膀胱:3.71

腎臓:-

下垂体:4.13

甲状腺:-

副腎:4.04

膵臓:5.65

乳腺:4.19

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:4.89

食道:-

胃:-

腸:-

結腸:-

肝臓:9.33

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008363
Gene ID	16179
Unigene ID	Mm.38241
Probe set ID	1438857_x_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031392

オーソログ対応遺伝子

ヒト[3]	NM_001025242, NM_001025243, NM_001569
ラット[1]	NM_001127555, NM_001025243, NM_001569

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0019221	cytokine-mediated signaling pathway
GO:0045087	innate immune response
GO:0070498	interleukin-1-mediated signaling pathway
GO:0007254	JNK cascade
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0016310	phosphorylation
GO:0043507	positive regulation of JUN kinase activity
GO:0043406	positive regulation of MAP kinase activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051259	protein oligomerization
GO:0001959	regulation of cytokine-mediated signaling pathway
GO:0070555	response to interleukin-1
GO:0032496	response to lipopolysaccharide
GO:0032494	response to peptidoglycan
GO:0007165	signal transduction
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005811	lipid particle
GO:0016020	membrane
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0005149	interleukin-1 receptor binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

interleukin-1 receptor-associated kinase 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function