interleukin 2

 詳細情報を見る

同義遺伝子名

interleukin 2, Interleukin-2 precursor, T-cell growth factor, IL-2, TCGF, Il-2, Il2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.20 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:21.60 末梢血:- 脾臓:- 胸腺:9.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.88 小脳:3.92 脳幹:- 脳梁:- 松果体:- 末梢神経:4.07 脊柱:3.95 網膜:4.15 目:4.45 動脈:- 静脈:3.99 リンパ節:4.09 末梢血:- 脾臓:4.16 胸腺:- 骨髄:3.99 脂肪:4.09 骨:4.17 皮膚:4.12
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:- リンパ節:1.03 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:132.40 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:3.69 胎盤:4.01 前立腺:4.03 卵巣:3.74 精巣:4.17 心臓:4.29 骨格筋:4.10 食道:- 胃:4.15 腸:3.99 結腸:- 肝臓:4.45 肺:3.94 膀胱:3.92 腎臓:4.25 下垂体:4.11 甲状腺:- 副腎:3.80 膵臓:4.44 乳腺:4.01 唾液腺:4.21
CAGE 子宮:0 胎盤:0 前立腺:0 卵巣:0 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0.23     肝臓:0    肺:0 膀胱:0 腎臓:- 下垂体:0 甲状腺:- 副腎:0 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:8.47 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_008366
Gene ID 16183
Unigene ID Mm.14190
Probe set ID 1449990_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027720

オーソログ対応遺伝子

ヒト[1]  NM_000586
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR009079  Four-helical cytokine-like, core
IPR000779  Interleukin-2

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006955  immune response
GO:0002903  negative regulation of B cell apoptosis
GO:0045822  negative regulation of heart contraction
GO:0050728  negative regulation of inflammatory response
GO:0050672  negative regulation of lymphocyte proliferation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0042104  positive regulation of activated T cell proliferation
GO:0030890  positive regulation of B cell proliferation
GO:0051024  positive regulation of immunoglobulin secretion
GO:0032729  positive regulation of interferon-gamma production
GO:0032740  positive regulation of interleukin-17 production
GO:0048304  positive regulation of isotype switching to IgG isotypes
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045591  positive regulation of regulatory T cell differentiation
GO:0045582  positive regulation of T cell differentiation
GO:0042102  positive regulation of T cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046013  regulation of T cell homeostatic proliferation

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0030246  carbohydrate binding
GO:0005125  cytokine activity
GO:0043208  glycosphingolipid binding
GO:0008083  growth factor activity
GO:0005134  interleukin-2 receptor binding
GO:0031851  kappa-type opioid receptor binding