interleukin 6

詳細情報を見る

IL-6, Il-6, Interleukin-6 precursor, Interleukin HP-1, interleukin 6, B-cell hybridoma growth factor, Il6

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

Refseq ID	NM_031168
Gene ID	16193
Unigene ID	Mm.101909
Probe set ID	1450297_at [Mouse430_2]
Ensembl ID	ENSMUSG00000025746

ヒト[1]	NM_000600
ラット [0]

IPR009079	Four-helical cytokine-like, core
IPR003574	Interleukin-6
IPR003573	Interleukin-6/G-CSF/MGF

GO:0006953	acute-phase response
GO:0060445	branching involved in salivary gland morphogenesis
GO:0016049	cell growth
GO:0045454	cell redox homeostasis
GO:0070301	cellular response to hydrogen peroxide
GO:0019221	cytokine-mediated signaling pathway
GO:0042832	defense response to protozoan
GO:0051607	defense response to virus
GO:0031018	endocrine pancreas development
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0070091	glucagon secretion
GO:0002384	hepatic immune response
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0070102	interleukin-6-mediated signaling pathway
GO:0046716	muscle homeostasis
GO:0043066	negative regulation of apoptosis
GO:0043154	negative regulation of caspase activity
GO:0008285	negative regulation of cell proliferation
GO:0045079	negative regulation of chemokine biosynthetic process
GO:0032966	negative regulation of collagen biosynthetic process
GO:0050710	negative regulation of cytokine secretion
GO:0045721	negative regulation of gluconeogenesis
GO:0046888	negative regulation of hormone secretion
GO:0048635	negative regulation of muscle organ development
GO:0006469	negative regulation of protein kinase activity
GO:0031175	neuron projection development
GO:0001781	neutrophil apoptosis
GO:0002675	positive regulation of acute inflammatory response
GO:0050871	positive regulation of B cell activation
GO:0008284	positive regulation of cell proliferation
GO:0032722	positive regulation of chemokine production
GO:0045740	positive regulation of DNA replication
GO:0050679	positive regulation of epithelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0010628	positive regulation of gene expression
GO:0051024	positive regulation of immunoglobulin secretion
GO:0032755	positive regulation of interleukin-6 production
GO:0046427	positive regulation of JAK-STAT cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0045666	positive regulation of neuron differentiation
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0033160	positive regulation of protein import into nucleus, translocation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0042102	positive regulation of T cell proliferation
GO:0045630	positive regulation of T-helper 2 cell differentiation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0045727	positive regulation of translation
GO:0051971	positive regulation of transmission of nerve impulse
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042981	regulation of apoptosis
GO:0042127	regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
GO:0010574	regulation of vascular endothelial growth factor production
GO:0051384	response to glucocorticoid stimulus
GO:0009611	response to wounding
GO:0042110	T cell activation

GO:0009897	external side of plasma membrane
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005896	interleukin-6 receptor complex

GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0005138	interleukin-6 receptor binding
GO:0005515	protein binding
GO:0005102	receptor binding

interleukin 6

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function