interleukin 6 receptor, alpha

詳細情報を見る

同義遺伝子名

interleukin 6 receptor, alpha, IL-6R-alpha, Il6r, Il6ra, CD126, IL-6 receptor alpha chain, CD126 antigen, IL-6R, IL-6R 1, Interleukin-6 receptor alpha chain precursor, MGC30256

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:14.40 脾臓:- 胸腺:29.60 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:5.26 小脳:5.06 脳幹:- 脳梁:- 松果体:- 末梢神経:5.88 脊柱:5.40 網膜:5.02 目:5.54 動脈:- 静脈:6.65 リンパ節:8.62 末梢血:- 脾臓:8.63 胸腺:- 骨髄:8.33 脂肪:7.02 骨:7.99 皮膚:9.47
CAGE 大脳:1.32 小脳:- 脳幹:1.56 脳梁:- 松果体:- 末梢神経:- 脊柱:1.47 網膜:- 目:- 動脈:3.28 静脈:- リンパ節:3.77 末梢血:- 脾臓:3.19 胸腺:2.07 骨髄:- 脂肪:- 骨:3.54 皮膚:4.08
RNA-seq 大脳:1.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:27.60 前立腺:- 卵巣:11.50 精巣:177.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:9.80 唾液腺:-
GeneChip 子宮:6.15 胎盤:8.44 前立腺:6.32 卵巣:6.31 精巣:5.24 心臓:6.24 骨格筋:6.42 食道:- 胃:5.90 腸:5.80 結腸:- 肝臓:8.55 肺:7.83 膀胱:7.06 腎臓:5.77 下垂体:7.31 甲状腺:- 副腎:7.03 膵臓:7.65 乳腺:6.95 唾液腺:6.38
CAGE 子宮:2.67 胎盤:3.86 前立腺:2.39 卵巣:2.48 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.91 腸:1.36 結腸:1.93     肝臓:4.17    肺:3.76 膀胱:2.82 腎臓:- 下垂体:2.85 甲状腺:- 副腎:2.38 膵臓:3.21 乳腺:3.80 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.27 食道:- 胃:- 腸:- 結腸:-     肝臓:3.96        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0016049  cell growth
GO:0070120  ciliary neurotrophic factor-mediated signaling pathway
GO:0019221  cytokine-mediated signaling pathway
GO:0031018  endocrine pancreas development
GO:0070102  interleukin-6-mediated signaling pathway
GO:0032966  negative regulation of collagen biosynthetic process
GO:0010536  positive regulation of activation of Janus kinase activity
GO:0008284  positive regulation of cell proliferation
GO:0032722  positive regulation of chemokine production
GO:0032755  positive regulation of interleukin-6 production
GO:0046427  positive regulation of JAK-STAT cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0034097  response to cytokine stimulus

Cellular Component

GO:0016324  apical plasma membrane
GO:0032809  cell soma membrane
GO:0009986  cell surface
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0005896  interleukin-6 receptor complex
GO:0016020  membrane

Molecular Function

GO:0070119  ciliary neurotrophic factor binding
GO:0004897  ciliary neurotrophic factor receptor activity
GO:0004896  cytokine receptor activity
GO:0019899  enzyme binding
GO:0019981  interleukin-6 binding
GO:0004915  interleukin-6 receptor activity
GO:0005138  interleukin-6 receptor binding
GO:0042803  protein homodimerization activity