interleukin 6 signal transducer

詳細情報を見る

同義遺伝子名

CD130 antigen, 5133400A03Rik, IL-6R-beta, Membrane glycoprotein 130, gp130, BB405851, CD130, AA389424, D13Ertd699e, Interleukin 6 signal transducer, Il6st, Interleukin-6 receptor beta chain precursor, interleukin 6 signal transducer

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:8.47 小脳:8.86 脳幹:- 脳梁:- 松果体:- 末梢神経:10.63 脊柱:9.24 網膜:8.39 目:9.02 動脈:- 静脈:10.66 リンパ節:11.17 末梢血:- 脾臓:10.06 胸腺:- 骨髄:8.78 脂肪:9.96 骨:9.52 皮膚:10.24
CAGE 大脳:3.74 小脳:- 脳幹:4.05 脳梁:- 松果体:- 末梢神経:- 脊柱:4.36 網膜:- 目:- 動脈:5.02 静脈:- リンパ節:5.45 末梢血:- 脾臓:3.83 胸腺:4.52 骨髄:- 脂肪:- 骨:4.31 皮膚:4.56
RNA-seq 大脳:5.45 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:11.52 胎盤:10.11 前立腺:9.58 卵巣:10.53 精巣:6.85 心臓:10.31 骨格筋:10.58 食道:- 胃:9.33 腸:9.02 結腸:- 肝臓:9.85 肺:11.20 膀胱:11.33 腎臓:9.34 下垂体:9.56 甲状腺:- 副腎:11.07 膵臓:8.68 乳腺:10.20 唾液腺:8.50
CAGE 子宮:5.50 胎盤:4.92 前立腺:3.95 卵巣:4.85 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:3.57 腸:3.22 結腸:3.50     肝臓:4.90    肺:5.07 膀胱:5.40 腎臓:- 下垂体:4.26 甲状腺:- 副腎:5.00 膵臓:4.36 乳腺:4.23 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:8.25 食道:- 胃:- 腸:- 結腸:-     肝臓:6.51        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010560
Gene ID 16195
Unigene ID Mm.436406
Probe set ID 1452843_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021756

オーソログ対応遺伝子

ヒト[10]  NM_001190981, NM_002184, NM_175767
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1542794
1602143
1915266
7621883
7957045
8552649
8607969
8666978
8843390
8889548
9122220
9324354
9348227
9500603
9558387
9743535
9815272
9874564
9920829
9933112
9988212
10205167
10219240
10349636
10486560
10564261
10661409
10725249
10922068
10989258
11042159
11076861
11160399
11217851
11262406
11275690
11457894
11493552
11567054
11877449
12047380
12070777
12097503
12147685
12219085
12370259
12423677
12466851
12477932
12509437
12518458
12520002
12629177
12691915
12754506
12830005
12891556
12900446
14597225
14600146
14610273
14617570
14699500
14749363
14755335
14978019
14996842
15051883
15073037
15207851
15292206
15356132
15607729
15634701
15650055
15677447
15716858
15761498
15852015
15976028
15996112
16014513
16041381
16118327
16141072
16141073
16143138
16250046
16286017
16319110
16452715
16452727
16679075
16717113
16818888
16825607
16905102
16906166
17030178
17053039
17082315
17101849
17105399
17114459
17179859
17182563
17241879
17249568
17256754
17299136
17493959
17567983
17603283
17609432
17664290
17674319
17688421
17961593
18185532
18216023
18236210
18431520
18467707
18519587
18593565
18641358
18684959
18714032
18805458
18848474
19015529
19050105
19097069
19109195
19121317
19136654
19185844
19213943
19228423
19501045
19538749
19592611
19593768
19646521
19665497
19805641
19852956
19864560
19948109
19948961
20005819
20016025
20042455
20051627
20062084
20091786
20100971
20144891
20200229
20238070
20348091
20353422
20382701
20530204
20554759
20585009
20707873
21035185
21079661
21090245
21148800
21162133
21241805
21267068
21297079
21515788
21565387
21606248
21677750
21710691
21990364
21995459
22007720
22082679
22100262
22140267
22268122
22304915
22306691
22323722
22523320
22567975
22640806
22645143
22715999
22745821
22798669
22911828
22986785
22999927
23091017
23192694
23209286
23306157
23321674
23335749
23809164
23885093
23888778
23948300
23993651
24069548
24081661
24191003

遺伝子オントロジー  (GO ID)

Biological Process

GO:0070120  ciliary neurotrophic factor-mediated signaling pathway
GO:0019221  cytokine-mediated signaling pathway
GO:0005977  glycogen metabolic process
GO:0070106  interleukin-27-mediated signaling pathway
GO:0070102  interleukin-6-mediated signaling pathway
GO:0048861  leukemia inhibitory factor signaling pathway
GO:0070104  negative regulation of interleukin-6-mediated signaling pathway
GO:0048711  positive regulation of astrocyte differentiation
GO:0008284  positive regulation of cell proliferation
GO:0045669  positive regulation of osteoblast differentiation
GO:0014911  positive regulation of smooth muscle cell migration
GO:0042102  positive regulation of T cell proliferation
GO:0042511  positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0051481  reduction of cytosolic calcium ion concentration
GO:0008593  regulation of Notch signaling pathway
GO:0034097  response to cytokine stimulus
GO:0007165  signal transduction
GO:0006642  triglyceride mobilization

Cellular Component

GO:0043025  cell soma
GO:0032809  cell soma membrane
GO:0070110  ciliary neurotrophic factor receptor complex
GO:0030425  dendrite
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0005896  interleukin-6 receptor complex
GO:0016020  membrane
GO:0005900  oncostatin-M receptor complex

Molecular Function

GO:0004897  ciliary neurotrophic factor receptor activity
GO:0005127  ciliary neurotrophic factor receptor binding
GO:0004896  cytokine receptor activity
GO:0019838  growth factor binding
GO:0019970  interleukin-11 binding
GO:0004921  interleukin-11 receptor activity
GO:0019981  interleukin-6 binding
GO:0004915  interleukin-6 receptor activity
GO:0005138  interleukin-6 receptor binding
GO:0004923  leukemia inhibitory factor receptor activity
GO:0004924  oncostatin-M receptor activity
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity