integrin linked kinase

詳細情報を見る

同義遺伝子名

integrin linked kinase, Integrin-linked protein kinase, Ilk, AA511515, ESTM24

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:66

小脳:-

脳幹:31.80

脳梁:-

松果体:-

末梢神経:133.80

脊柱:141.90

網膜:96.40

目:45.60

動脈:-

静脈:-

リンパ節:32.40

末梢血:14.40

脾臓:39.50

胸腺:-

骨髄:102.60

脂肪:-

骨:225.40

皮膚:110.80

GeneChip

大脳:9.17

小脳:9.52

脳幹:-

脳梁:-

松果体:-

末梢神経:10.34

脊柱:9.49

網膜:8.37

目:8.71

動脈:-

静脈:10.70

リンパ節:9.91

末梢血:-

脾臓:10.08

胸腺:-

骨髄:10.84

脂肪:10.17

骨:10.58

皮膚:8.82

CAGE

大脳:3.32

小脳:-

脳幹:3.40

脳梁:-

松果体:-

末梢神経:-

脊柱:3.39

網膜:-

目:-

動脈:4.57

静脈:-

リンパ節:3.78

末梢血:-

脾臓:4.12

胸腺:3.46

骨髄:-

脂肪:-

骨:4.42

皮膚:3.46

RNA-seq

大脳:12.95

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:55.20

前立腺:30.90

卵巣:34.50

精巣:51.70

心臓:111.60

骨格筋:35.50

食道:-

胃:130.90

腸:-

結腸:52.90

肝臓:45.30

肺:100.40

膀胱:198.50

腎臓:40.30

下垂体:180.80

甲状腺:-

副腎:-

膵臓:37.50

乳腺:117.50

唾液腺:54

GeneChip

子宮:11.38

胎盤:10.54

前立腺:10.01

卵巣:10.98

精巣:8.38

心臓:9.98

骨格筋:9.65

食道:-

胃:9.76

腸:9.56

結腸:-

肝臓:9.48

肺:10.83

膀胱:11.22

腎臓:9.77

下垂体:10.23

甲状腺:-

副腎:9.57

膵臓:8.93

乳腺:9.70

唾液腺:8.97

CAGE

子宮:4.71

胎盤:4.41

前立腺:3.95

卵巣:4.39

精巣:2.82

心臓:-

骨格筋:-

食道:-

胃:4.37

腸:3.42

結腸:3.50

肝臓:3.55

肺:4.36

膀胱:4.82

腎臓:-

下垂体:3.74

甲状腺:-

副腎:3.89

膵臓:3.45

乳腺:3.91

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:8.16

食道:-

胃:-

腸:-

結腸:-

肝臓:9.50

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001161724
Gene ID	16202
Unigene ID	Mm.274846
Probe set ID	1449942_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000030890

オーソログ対応遺伝子

ヒト[6]	NM_001014794, NM_001014795, NM_004517
ラット[1]	NM_133409, NM_001014795, NM_004517

染色体

7E3 [112,885,106 - 112,891,439]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001658	branching involved in ureteric bud morphogenesis
GO:0007569	cell aging
GO:0007050	cell cycle arrest
GO:0030030	cell projection organization
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
GO:0043206	fibril organization
GO:0007229	integrin-mediated signaling pathway
GO:0032288	myelin assembly
GO:0022011	myelination in the peripheral nervous system
GO:0043066	negative regulation of apoptosis
GO:0010667	negative regulation of cardiac muscle cell apoptosis
GO:0043524	negative regulation of neuron apoptosis
GO:0006469	negative regulation of protein kinase activity
GO:0014912	negative regulation of smooth muscle cell migration
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0021675	nerve development
GO:0048812	neuron projection morphogenesis
GO:0018105	peptidyl-serine phosphorylation
GO:0016310	phosphorylation
GO:0045773	positive regulation of axon extension
GO:0050772	positive regulation of axonogenesis
GO:0030513	positive regulation of BMP signaling pathway
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0001954	positive regulation of cell-matrix adhesion
GO:0050775	positive regulation of dendrite morphogenesis
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0045663	positive regulation of myoblast differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0042327	positive regulation of phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0043491	protein kinase B signaling cascade
GO:0032956	regulation of actin cytoskeleton organization
GO:0001558	regulation of cell growth
GO:0009966	regulation of signal transduction
GO:0014044	Schwann cell development
GO:0034446	substrate adhesion-dependent cell spreading

Cellular Component

GO:0030424	axon
GO:0030054	cell junction
GO:0042995	cell projection
GO:0043025	cell soma
GO:0005911	cell-cell junction
GO:0043034	costamere
GO:0005737	cytoplasm
GO:0043198	dendritic shaft
GO:0005925	focal adhesion
GO:0030027	lamellipodium
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0001725	stress fiber
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0005178	integrin binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity
GO:0017124	SH3 domain binding
GO:0004871	signal transducer activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

integrin linked kinase

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function