inositol polyphosphate-5-phosphatase D

詳細情報を見る

同義遺伝子名

s-SHIP, Inpp5d, inositol polyphosphate-5-phosphatase D, 145kDa, SHIP, AI323613, SHIP-1, MGC117680

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:31.30 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:152.90 脊柱:- 網膜:- 目:30.40 動脈:- 静脈:- リンパ節:496.90 末梢血:86.30 脾臓:92.20 胸腺:197.60 骨髄:- 脂肪:- 骨:187.90 皮膚:15.80
GeneChip 大脳:6.80 小脳:6.18 脳幹:- 脳梁:- 松果体:- 末梢神経:6.42 脊柱:6.69 網膜:6.60 目:6.86 動脈:- 静脈:7.03 リンパ節:10.72 末梢血:- 脾臓:11.02 胸腺:- 骨髄:10.44 脂肪:7.80 骨:9.85 皮膚:6.80
CAGE 大脳:1.87 小脳:- 脳幹:2.21 脳梁:- 松果体:- 末梢神経:- 脊柱:2.46 網膜:- 目:- 動脈:3.08 静脈:- リンパ節:5.39 末梢血:- 脾臓:4.56 胸腺:4.47 骨髄:- 脂肪:- 骨:4.61 皮膚:2.85
RNA-seq 大脳:1.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:34.50 精巣:7.40 心臓:55.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:45.30        肺:110.50    膀胱:- 腎臓:- 下垂体:51.70 甲状腺:112.50 副腎:- 膵臓:- 乳腺:16.30 唾液腺:-
GeneChip 子宮:8.29 胎盤:6.90 前立腺:6.56 卵巣:7.18 精巣:7.35 心臓:7.38 骨格筋:7 食道:- 胃:7 腸:7.18 結腸:- 肝臓:6.84 肺:8.86 膀胱:6.96 腎臓:7.08 下垂体:6.79 甲状腺:- 副腎:7.29 膵臓:6.56 乳腺:7.70 唾液腺:7.04
CAGE 子宮:3.32 胎盤:2.37 前立腺:1.80 卵巣:2.58 精巣:2.12 心臓:- 骨格筋:- 食道:- 胃:1.91 腸:2.03 結腸:2.96     肝臓:2.13    肺:4.08 膀胱:2.59 腎臓:- 下垂体:1.69 甲状腺:- 副腎:3.48 膵臓:2.56 乳腺:2.86 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.24 食道:- 胃:- 腸:- 結腸:-     肝臓:1.58        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001110193
Gene ID 16331
Unigene ID Mm.15105
Probe set ID 1418110_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026288

オーソログ対応遺伝子

ヒト[8]  NM_001017915, NM_005541
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8643691
8654924
8723348
8805618
8890215
9027494
9108392
9110989
9244303
9393882
9525932
9560157
9620849
9736736
9763612
9857188
10068665
10197978
10349636
10433813
10606629
10704460
10716940
10748054
10790429
10829070
10856225
10861044
10891441
11013080
11031258
11042159
11076861
11136821
11217851
11418650
11477403
11567986
11724799
11781306
11896280
11970986
11971024
12008029
12161749
12384440
12466851
12477932
12595903
12692707
12829595
12855581
12874256
12874264
12882960
12885297
12893283
12904583
14610273
14681479
14718513
15001465
15102471
15166241
15196208
15210764
15210794
15215307
15308103
15339845
15456754
15486046
15494015
15585856
15611277
15655368
15701712
15760467
15831701
15870290
15944314
15953601
15978570
15990278
16141072
16141073
16204085
16226502
16467196
16543474
16547230
16601135
16751359
16783635
17105399
17142780
17173042
17239631
17277160
17312133
17339427
17347685
17363732
17379073
17442886
17475876
17498626
17502453
17540781
17585010
17631919
17682126
17947710
17967808
18056340
18246197
18424711
18426884
18490750
18791164
18799693
18958162
19074735
19136659
19139077
19494109
19520806
19542365
19542434
19587372
19703514
19710468
19936232
20041145
20100929
20154203
20200281
20304029
20308635
20351305
20363967
20385881
20445019
20484116
20526344
20697350
20720161
20810657
20956547
21131429
21151496
21267068
21339365
21421839
21423172
21469115
21572033
21622861
21640975
21685246
21697469
21725061
21755007
21791431
21791602
21793801
21934070
22078222
22131333
22132131
22182704
22323291
22370159
22430739
22491248
22535180
22535653
22651931
22683124
22689883
22798664
22922362
22955274
23034281
23135975
23209322
23479228
23725762
23911388
24218606
24223520

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0016311  dephosphorylation
GO:0008340  determination of adult lifespan
GO:0016064  immunoglobulin mediated immune response
GO:0050869  negative regulation of B cell activation
GO:0030889  negative regulation of B cell proliferation
GO:0045779  negative regulation of bone resorption
GO:0008285  negative regulation of cell proliferation
GO:0030853  negative regulation of granulocyte differentiation
GO:0050777  negative regulation of immune response
GO:0045409  negative regulation of interleukin-6 biosynthetic process
GO:0045656  negative regulation of monocyte differentiation
GO:0045659  negative regulation of neutrophil differentiation
GO:0045671  negative regulation of osteoclast differentiation
GO:0009968  negative regulation of signal transduction
GO:0046856  phosphoinositide dephosphorylation
GO:0043065  positive regulation of apoptosis
GO:0045579  positive regulation of B cell differentiation
GO:0045648  positive regulation of erythrocyte differentiation
GO:0045621  positive regulation of lymphocyte differentiation

Cellular Component

GO:0005884  actin filament
GO:0030863  cortical cytoskeleton
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0016787  hydrolase activity
GO:0030487  inositol-4,5-bisphosphate 5-phosphatase activity
GO:0004445  inositol-polyphosphate 5-phosphatase activity
GO:0034594  phosphatidylinositol trisphosphate phosphatase activity
GO:0005515  protein binding
GO:0051425  PTB domain binding
GO:0017124  SH3 domain binding