insulin receptor

詳細情報を見る

同義遺伝子名

Insr, CD220, CD220 antigen, Insulin receptor precursor, 4932439J01Rik, IR, insulin receptor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:33

小脳:55.30

脳幹:158.90

脳梁:-

松果体:-

末梢神経:38.20

脊柱:-

網膜:96.40

目:83.60

動脈:-

静脈:-

リンパ節:10.80

末梢血:28.80

脾臓:65.80

胸腺:29.60

骨髄:-

脂肪:-

骨:12.50

皮膚:87.10

GeneChip

nodata

CAGE

大脳:3.78

小脳:-

脳幹:3.57

脳梁:-

松果体:-

末梢神経:-

脊柱:3.60

網膜:-

目:-

動脈:4.07

静脈:-

リンパ節:3.08

末梢血:-

脾臓:2.94

胸腺:3.75

骨髄:-

脂肪:-

骨:3.71

皮膚:3.61

RNA-seq

nodata

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:30.90

卵巣:11.50

精巣:22.20

心臓:74.40

骨格筋:-

食道:-

胃:-

腸:-

結腸:52.90

肝臓:45.30

肺:70.30

膀胱:-

腎臓:96.70

下垂体:12.90

甲状腺:-

副腎:424.40

膵臓:18.80

乳腺:78.40

唾液腺:54

GeneChip

nodata

CAGE

子宮:3.83

胎盤:3.46

前立腺:3.90

卵巣:4.15

精巣:0.99

心臓:-

骨格筋:-

食道:-

胃:2.85

腸:3.87

結腸:3.75

肝臓:4.57

肺:3.91

膀胱:4.03

腎臓:-

下垂体:4.31

甲状腺:-

副腎:4.52

膵臓:4.30

乳腺:3.75

唾液腺:-

RNA-seq

nodata

IDs

Refseq ID	NM_001033381
Gene ID	16337
Unigene ID	Mm.268003
Probe set ID	-
Ensembl ID	-

オーソログ対応遺伝子

ヒト [0]
ラット [0]

染色体

8A1.1 [3,150,922 - 3,279,617]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0071363	cellular response to growth factor stimulus
GO:0032869	cellular response to insulin stimulus
GO:0031017	exocrine pancreas development
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042593	glucose homeostasis
GO:0003007	heart morphogenesis
GO:0008286	insulin receptor signaling pathway
GO:0030238	male sex determination
GO:0010629	negative regulation of gene expression
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0032410	negative regulation of transporter activity
GO:0009887	organ morphogenesis
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0048639	positive regulation of developmental growth
GO:0045740	positive regulation of DNA replication
GO:0046326	positive regulation of glucose import
GO:0045725	positive regulation of glycogen biosynthetic process
GO:0045821	positive regulation of glycolysis
GO:0010560	positive regulation of glycoprotein biosynthetic process
GO:0043410	positive regulation of MAPKKK cascade
GO:0045840	positive regulation of mitosis
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0042327	positive regulation of phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0060267	positive regulation of respiratory burst
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051290	protein heterotetramerization
GO:0045995	regulation of embryonic development
GO:0010310	regulation of hydrogen peroxide metabolic process
GO:0006355	regulation of transcription, DNA-dependent
GO:0034612	response to tumor necrosis factor
GO:0019087	transformation of host cell by virus
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005901	caveola
GO:0005829	cytosol
GO:0005768	endosome
GO:0005899	insulin receptor complex
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0045202	synapse

Molecular Function

GO:0043423	3-phosphoinositide-dependent protein kinase binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0043559	insulin binding
GO:0005009	insulin receptor activity
GO:0043560	insulin receptor substrate binding
GO:0031994	insulin-like growth factor I binding
GO:0031995	insulin-like growth factor II binding
GO:0005159	insulin-like growth factor receptor binding
GO:0016301	kinase activity
GO:0031405	lipoic acid binding
GO:0000166	nucleotide binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0019904	protein domain specific binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0004713	protein tyrosine kinase activity
GO:0051425	PTB domain binding
GO:0004716	receptor signaling protein tyrosine kinase activity
GO:0042169	SH2 domain binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

insulin receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function