interferon regulatory factor 1

詳細情報を見る

同義遺伝子名

interferon regulatory factor 1, Irf1, IRF-1, Interferon regulatory factor 1, Irf-1, AU020929

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:76.40 脊柱:- 網膜:32.10 目:22.80 動脈:- 静脈:- リンパ節:86.40 末梢血:632.60 脾臓:987.50 胸腺:49.40 骨髄:487.20 脂肪:1063.60 骨:25 皮膚:55.40
GeneChip 大脳:7.19 小脳:6.95 脳幹:- 脳梁:- 松果体:- 末梢神経:7.86 脊柱:7.40 網膜:7.79 目:9.07 動脈:- 静脈:7.73 リンパ節:10.78 末梢血:- 脾臓:10.95 胸腺:- 骨髄:9.20 脂肪:8.91 骨:8.97 皮膚:8.49
CAGE 大脳:1.74 小脳:- 脳幹:1.86 脳梁:- 松果体:- 末梢神経:- 脊柱:1.73 網膜:- 目:- 動脈:3.74 静脈:- リンパ節:4.74 末梢血:- 脾臓:4.06 胸腺:4.26 骨髄:- 脂肪:- 骨:3.73 皮膚:2.99
RNA-seq 大脳:1.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:80.40 精巣:73.90 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:480.60 結腸:246.70     肝臓:54.30        肺:241    膀胱:- 腎臓:32.20 下垂体:- 甲状腺:224.90 副腎:- 膵臓:18.80 乳腺:212.20 唾液腺:108
GeneChip 子宮:9.68 胎盤:8.18 前立腺:9.03 卵巣:8.90 精巣:7.42 心臓:8.66 骨格筋:8.57 食道:- 胃:9.28 腸:10.94 結腸:- 肝臓:8.96 肺:10.38 膀胱:8.58 腎臓:8.31 下垂体:9.06 甲状腺:- 副腎:8.64 膵臓:8.45 乳腺:9.27 唾液腺:8.93
CAGE 子宮:3.89 胎盤:2.72 前立腺:2.88 卵巣:3.41 精巣:1.48 心臓:- 骨格筋:- 食道:- 胃:3.51 腸:5.01 結腸:5.25     肝臓:3.78    肺:4.70 膀胱:3.35 腎臓:- 下垂体:3.49 甲状腺:- 副腎:3.65 膵臓:3.10 乳腺:3.18 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.53 食道:- 胃:- 腸:- 結腸:-     肝臓:3.67        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008390
Gene ID 16362
Unigene ID Mm.105218
Probe set ID 1448436_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000018899

オーソログ対応遺伝子

ヒト[1]  NM_002198
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1296455
1358285
1442307
2111015
2475256
2911367
3409321
7510419
7567467
7636205
7650042
7654369
7822029
7823961
7843405
7957048
8009222
8265581
8402903
8595891
8617930
8885869
8889548
9070927
9078371
9126988
9144426
9149945
9177770
9208840
9244230
9285409
9294015
9317154
9379011
9422515
9472983
9551885
9754575
9850859
9973388
9989987
10225884
10346812
10349636
10364426
10415056
10421776
10438942
10477397
10524230
10586082
10655497
10704283
10725249
10859338
10930443
10934221
11034406
11042159
11076861
11160382
11175354
11179500
11180100
11217851
11244049
11359801
11380074
11418690
11591120
11716756
11846972
11846974
11854220
11859135
12055269
12387893
12429737
12466851
12477932
12499398
12516771
12517966
12537697
12592391
12759449
12807824
12902503
12947309
12960317
13679855
14568984
14610273
14651778
14762441
14976252
15238077
15240709
15246962
15307168
15351786
15385939
15451476
15489234
15489334
15494505
15618518
15740479
15780087
15800576
15860458
15871905
16022283
16024814
16123129
16141072
16141073
16183743
16210330
16284791
16293660
16410367
16484540
16541466
16707500
16791898
16966383
17018642
17159910
17170083
17200147
17227910
17273999
17293456
17468758
17475277
18059273
18060035
18287559
18401006
18424746
18641303
18652890
18802049
18955028
19041738
19075017
19201871
19429811
19430477
19443641
19652017
19720760
19756487
20059953
20083668
20131404
20194591
20308629
20412781
20422028
20435892
20451243
20599664
20624945
20631312
20637660
20856174
21267068
21282509
21480215
21624938
21653838
21677750
21725055
21820332
21900395
21903422
21909274
22042864
22185785
22229156
22252317
22266972
22345458
22366192
22464096
22636321
22777843
22896628
22962685
22973039
23154982
23326354
23383295
23444404
23554911
23623383
23657854
23863621
23903655
23975864
24140644
24214980
24464131
24532583

遺伝子オントロジー  (GO ID)

Biological Process

GO:0043374  CD8-positive, alpha-beta T cell differentiation
GO:0007050  cell cycle arrest
GO:0071347  cellular response to interleukin-1
GO:0071375  cellular response to peptide hormone stimulus
GO:0071356  cellular response to tumor necrosis factor
GO:0051607  defense response to virus
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0006917  induction of apoptosis
GO:0045087  innate immune response
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0045590  negative regulation of regulatory T cell differentiation
GO:0045629  negative regulation of T-helper 2 cell differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042512  negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0010942  positive regulation of cell death
GO:0032728  positive regulation of interferon-beta production
GO:0045084  positive regulation of interleukin-12 biosynthetic process
GO:0032825  positive regulation of natural killer cell differentiation
GO:0045627  positive regulation of T-helper 1 cell differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032481  positive regulation of type I interferon production
GO:0002819  regulation of adaptive immune response
GO:0010468  regulation of gene expression
GO:0045088  regulation of innate immune response
GO:0034124  regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0006355  regulation of transcription, DNA-dependent
GO:0060416  response to growth hormone stimulus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity