integrin alpha V

詳細情報を見る

同義遺伝子名

2610028E01Rik, CD51, alphav-integrin, Itgav, Integrin alpha-V precursor, Vitronectin receptor subunit alpha, vitronectin receptor alpha polypeptide (VNRA), integrin alpha V, 1110004F14Rik, CD51 antigen

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.24 小脳:5.26 脳幹:- 脳梁:- 松果体:- 末梢神経:5.20 脊柱:5.30 網膜:5.12 目:5.31 動脈:- 静脈:5.31 リンパ節:5.57 末梢血:- 脾臓:5.65 胸腺:- 骨髄:5.21 脂肪:5.30 骨:5.08 皮膚:4.98
CAGE 大脳:3.44 小脳:- 脳幹:3.95 脳梁:- 松果体:- 末梢神経:- 脊柱:4.40 網膜:- 目:- 動脈:3.86 静脈:- リンパ節:3.88 末梢血:- 脾臓:3.28 胸腺:3.37 骨髄:- 脂肪:- 骨:3.64 皮膚:4.04
RNA-seq 大脳:2.28 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.42 胎盤:6.08 前立腺:5.23 卵巣:5.36 精巣:5.43 心臓:5.66 骨格筋:5.41 食道:- 胃:5.22 腸:5.24 結腸:- 肝臓:5.51 肺:5.18 膀胱:5.28 腎臓:5.94 下垂体:5.32 甲状腺:- 副腎:4.91 膵臓:5.61 乳腺:5.38 唾液腺:5.34
CAGE 子宮:4.61 胎盤:5.14 前立腺:4.06 卵巣:4.61 精巣:2.05 心臓:- 骨格筋:- 食道:- 胃:3.72 腸:3.33 結腸:3.41     肝臓:3.66    肺:3.91 膀胱:4.25 腎臓:- 下垂体:3.17 甲状腺:- 副腎:4.20 膵臓:3.45 乳腺:4.21 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.42 食道:- 胃:- 腸:- 結腸:-     肝臓:2.85        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008402
Gene ID 16410
Unigene ID -
Probe set ID 1432296_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027087

オーソログ対応遺伝子

ヒト[3]  NM_001144999, NM_001145000, NM_002210
ラット[3]  NM_001144999, NM_001145000, NM_002210

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0043277  apoptotic cell clearance
GO:0001568  blood vessel development
GO:0070588  calcium ion transmembrane transport
GO:0007155  cell adhesion
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0007160  cell-matrix adhesion
GO:0006874  cellular calcium ion homeostasis
GO:0032490  detection of molecule of bacterial origin
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0043542  endothelial cell migration
GO:0070371  ERK1 and ERK2 cascade
GO:0009566  fertilization
GO:0048041  focal adhesion formation
GO:0035262  gonad morphogenesis
GO:0006954  inflammatory response
GO:0007229  integrin-mediated signaling pathway
GO:0007275  multicellular organismal development
GO:0010888  negative regulation of lipid storage
GO:0032369  negative regulation of lipid transport
GO:0050748  negative regulation of lipoprotein metabolic process
GO:0045715  negative regulation of low-density lipoprotein receptor biosynthetic process
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0045785  positive regulation of cell adhesion
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0043410  positive regulation of MAPKKK cascade
GO:0033690  positive regulation of osteoblast proliferation
GO:0045124  regulation of bone resorption
GO:0050764  regulation of phagocytosis
GO:0051209  release of sequestered calcium ion into cytosol
GO:0042110  T cell activation
GO:0060707  trophoblast giant cell differentiation

Cellular Component

GO:0034683  alphav-beta3 integrin complex
GO:0009986  cell surface
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0008305  integrin complex
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0031994  insulin-like growth factor I binding
GO:0046872  metal ion binding
GO:0001846  opsonin binding
GO:0042277  peptide binding
GO:0046982  protein heterodimerization activity
GO:0005080  protein kinase C binding
GO:0005102  receptor binding
GO:0005245  voltage-gated calcium channel activity