Janus kinase 3

詳細情報を見る

同義遺伝子名

wil, Jak3, JAK-3, Janus kinase 3, Tyrosine-protein kinase JAK3, fae

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:8.70

小脳:18.40

脳幹:-

脳梁:-

松果体:-

末梢神経:152.90

脊柱:-

網膜:32.10

目:-

動脈:-

静脈:-

リンパ節:140.40

末梢血:776.40

脾臓:316

胸腺:168

骨髄:38.50

脂肪:212.70

骨:-

皮膚:7.90

GeneChip

大脳:3.84

小脳:3.99

脳幹:-

脳梁:-

松果体:-

末梢神経:3.89

脊柱:3.81

網膜:4.02

目:4.06

動脈:-

静脈:3.99

リンパ節:4

末梢血:-

脾臓:3.82

胸腺:-

骨髄:3.84

脂肪:3.98

骨:3.95

皮膚:4.12

CAGE

大脳:0.94

小脳:-

脳幹:1.46

脳梁:-

松果体:-

末梢神経:-

脊柱:1.38

網膜:-

目:-

動脈:2.95

静脈:-

リンパ節:4.12

末梢血:-

脾臓:3.33

胸腺:2.78

骨髄:-

脂肪:-

骨:2.59

皮膚:1.42

RNA-seq

大脳:1.42

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:69

前立腺:-

卵巣:23

精巣:44.30

心臓:74.40

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:60.30

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:848.90

膵臓:-

乳腺:42.40

唾液腺:108

GeneChip

子宮:3.80

胎盤:3.87

前立腺:3.84

卵巣:3.81

精巣:4.51

心臓:4.04

骨格筋:3.96

食道:-

胃:3.79

腸:4.06

結腸:-

肝臓:4.04

肺:3.86

膀胱:3.85

腎臓:4.06

下垂体:3.98

甲状腺:-

副腎:3.92

膵臓:4.36

乳腺:3.80

唾液腺:4.22

CAGE

子宮:3.09

胎盤:2.94

前立腺:0.74

卵巣:2.09

精巣:0.75

心臓:-

骨格筋:-

食道:-

胃:1.91

腸:2.22

結腸:2.24

肝臓:2.13

肺:3.47

膀胱:2.40

腎臓:-

下垂体:1.81

甲状腺:-

副腎:2.84

膵臓:1.30

乳腺:2.87

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.67

食道:-

胃:-

腸:-

結腸:-

肝臓:1.98

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010589
Gene ID	16453
Unigene ID	Mm.249645
Probe set ID	1427092_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031805

オーソログ対応遺伝子

ヒト[2]	NM_000215
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0030183	B cell differentiation
GO:0019221	cytokine-mediated signaling pathway
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0007167	enzyme linked receptor protein signaling pathway
GO:0045087	innate immune response
GO:0048535	lymph node development
GO:0002731	negative regulation of dendritic cell cytokine production
GO:0045221	negative regulation of FasL biosynthetic process
GO:0032693	negative regulation of interleukin-10 production
GO:0032695	negative regulation of interleukin-12 production
GO:0050868	negative regulation of T cell activation
GO:0045626	negative regulation of T-helper 1 cell differentiation
GO:0070244	negative regulation of thymocyte apoptosis
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0042104	positive regulation of activated T cell proliferation
GO:0051928	positive regulation of calcium ion transport
GO:0050778	positive regulation of immune response
GO:0042102	positive regulation of T cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0007243	protein kinase cascade
GO:0070232	regulation of T cell apoptosis
GO:0070672	response to interleukin-15
GO:0070669	response to interleukin-2
GO:0070670	response to interleukin-4
GO:0071104	response to interleukin-9
GO:0043029	T cell homeostasis
GO:0042506	tyrosine phosphorylation of Stat5 protein

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005622	intracellular
GO:0016020	membrane

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019903	protein phosphatase binding
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

IPR019749	Band 4.1 domain
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR016251	Tyrosine-protein kinase, non-receptor Jak/Tyk2
IPR020775	Tyrosine-protein kinase, non-receptor Jak3
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Janus kinase 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function