large tumor suppressor

 詳細情報を見る

同義遺伝子名

Serine/threonine-protein kinase LATS1, Warts, Lats1, large tumor suppressor, Large tumor suppressor homolog 1, WARTS protein kinase

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:39.90 小脳:221 脳幹:31.80 脳梁:- 松果体:- 末梢神経:19.10 脊柱:94.60 網膜:- 目:30.40 動脈:- 静脈:- リンパ節:43.20 末梢血:43.10 脾臓:13.20 胸腺:118.60 骨髄:153.90 脂肪:- 骨:50.10 皮膚:31.70
GeneChip nodata
CAGE 大脳:3.51 小脳:- 脳幹:3.35 脳梁:- 松果体:- 末梢神経:- 脊柱:3.65 網膜:- 目:- 動脈:4.02 静脈:- リンパ節:4.09 末梢血:- 脾臓:3.18 胸腺:3.65 骨髄:- 脂肪:- 骨:3.52 皮膚:4.15
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:43.60 胎盤:27.60 前立腺:- 卵巣:46 精巣:36.90 心臓:- 骨格筋:106.50 食道:- 胃:32.70 腸:- 結腸:17.60     肝臓:-        肺:50.20    膀胱:66.20 腎臓:16.10 下垂体:- 甲状腺:- 副腎:- 膵臓:112.60 乳腺:94.70 唾液腺:108
GeneChip nodata
CAGE 子宮:3.83 胎盤:3.43 前立腺:3.95 卵巣:3.79 精巣:3.78 心臓:- 骨格筋:- 食道:- 胃:2.95 腸:3.87 結腸:3.90     肝臓:3.44    肺:3.72 膀胱:3.52 腎臓:- 下垂体:3.97 甲状腺:- 副腎:3.78 膵臓:4.32 乳腺:3.98 唾液腺:-
RNA-seq nodata

詳細情報

IDs

Refseq ID XM_906240
Gene ID 16798
Unigene ID Mm.34083
Probe set ID -
Ensembl ID -

オーソログ対応遺伝子

ヒト [0]  
ラット [0]  

染色体

10A1  [7,401,007  -  7,436,256]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain
IPR000449  Ubiquitin-associated/translation elongation factor EF1B, N-terminal
IPR015940  Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

Link to Pubmed  (Pubmed ID)

7743921
8889548
9988268
9988269
10349636
10528150
11042159
11076861
11217851
12466851
12477932
14610273
15031102
15343267
16141072
16141073
18369314
18640976
19289085
19656388
19786569
20407010
20643348
21145499
21233212
21267068
21303848
21808298
22187428
22641346
23071096
23230145
23593160
23620511
23644383
23824537
24255096

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0051301  cell division
GO:0034613  cellular protein localization
GO:0051220  cytoplasmic sequestering of protein
GO:0000086  G2/M transition of mitotic cell cycle
GO:0009755  hormone-mediated signaling pathway
GO:0030216  keratinocyte differentiation
GO:0007067  mitosis
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0016310  phosphorylation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0030833  regulation of actin filament polymerization
GO:0043254  regulation of protein complex assembly
GO:0000819  sister chromatid segregation

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0000922  spindle pole

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0000287  magnesium ion binding
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups