lymphoid enhancer binding factor 1

詳細情報を見る

同義遺伝子名

3000002B05, lymphoid enhancer factor 1, AI451430, Lef1, LEF-1, lymphoid enhancer binding factor 1, Lef-1, Lymphoid enhancer-binding factor 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:33 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:- 目:- 動脈:84.40 静脈:- リンパ節:32.40 末梢血:143.80 脾臓:92.20 胸腺:415 骨髄:- 脂肪:- 骨:12.50 皮膚:79.20
GeneChip 大脳:4.55 小脳:4.42 脳幹:- 脳梁:- 松果体:- 末梢神経:4.28 脊柱:4.55 網膜:4.28 目:4.55 動脈:- 静脈:4.62 リンパ節:8.15 末梢血:- 脾臓:7.18 胸腺:- 骨髄:4.98 脂肪:4.68 骨:4.33 皮膚:4.28
CAGE 大脳:2.26 小脳:- 脳幹:3.09 脳梁:- 松果体:- 末梢神経:- 脊柱:2.43 網膜:- 目:- 動脈:1.32 静脈:- リンパ節:5.30 末梢血:- 脾臓:3.08 胸腺:5.49 骨髄:- 脂肪:- 骨:1.69 皮膚:4.10
RNA-seq 大脳:1.53 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:- 前立腺:- 卵巣:68.90 精巣:81.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:8.10 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:5.17 胎盤:4.16 前立腺:4.10 卵巣:4.10 精巣:7.93 心臓:4.63 骨格筋:4.41 食道:- 胃:4.21 腸:4.06 結腸:- 肝臓:4.19 肺:4.89 膀胱:4.19 腎臓:4.25 下垂体:4.34 甲状腺:- 副腎:4.66 膵臓:4.53 乳腺:4.99 唾液腺:4.27
CAGE 子宮:1.90 胎盤:1.40 前立腺:1.69 卵巣:1.76 精巣:4.80 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:0.58 結腸:0.93     肝臓:0.26    肺:2.89 膀胱:1.54 腎臓:- 下垂体:1.75 甲状腺:- 副腎:2.84 膵臓:1.30 乳腺:1.62 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.42 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010703
Gene ID 16842
Unigene ID Mm.255219
Probe set ID 1421299_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027985

オーソログ対応遺伝子

ヒト[8]  NM_001130713, NM_001130714, NM_001166119, NM_016269
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1783375
1827423
2108401
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0046632  alpha-beta T cell differentiation
GO:0060033  anatomical structure regression
GO:0060561  apoptosis involved in morphogenesis
GO:0042100  B cell proliferation
GO:0030509  BMP signaling pathway
GO:0060326  cell chemotaxis
GO:0048468  cell development
GO:0071345  cellular response to cytokine stimulus
GO:0071353  cellular response to interleukin-4
GO:0060710  chorio-allantoic fusion
GO:0021542  dentate gyrus development
GO:0030326  embryonic limb morphogenesis
GO:0001837  epithelial to mesenchymal transition
GO:0030520  estrogen receptor signaling pathway
GO:0048069  eye pigmentation
GO:0060325  face morphogenesis
GO:0021873  forebrain neuroblast division
GO:0021879  forebrain neuron differentiation
GO:0021943  formation of radial glial scaffolds
GO:0021766  hippocampus development
GO:0043966  histone H3 acetylation
GO:0043967  histone H4 acetylation
GO:0021854  hypothalamus development
GO:0030879  mammary gland development
GO:0048747  muscle fiber development
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0022408  negative regulation of cell-cell adhesion
GO:0043392  negative regulation of DNA binding
GO:0032696  negative regulation of interleukin-13 production
GO:0032713  negative regulation of interleukin-4 production
GO:0032714  negative regulation of interleukin-5 production
GO:0045843  negative regulation of striated muscle tissue development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001755  neural crest cell migration
GO:0030223  neutrophil differentiation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0001649  osteoblast differentiation
GO:0060021  palate development
GO:0048341  paraxial mesoderm formation
GO:0001569  patterning of blood vessels
GO:0043923  positive regulation by host of viral transcription
GO:0090068  positive regulation of cell cycle process
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0022409  positive regulation of cell-cell adhesion
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0010628  positive regulation of gene expression
GO:0030854  positive regulation of granulocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0021861  radial glial cell differentiation in the forebrain
GO:0022407  regulation of cell-cell adhesion
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0050909  sensory perception of taste
GO:0001756  somitogenesis
GO:0002040  sprouting angiogenesis
GO:0033153  T cell receptor V(D)J recombination
GO:0045063  T-helper 1 cell differentiation
GO:0043586  tongue development
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0001944  vasculature development
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0032993  protein-DNA complex
GO:0005667  transcription factor complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0008013  beta-catenin binding
GO:0070742  C2H2 zinc finger domain binding
GO:0043027  caspase inhibitor activity
GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0030284  estrogen receptor activity
GO:0030331  estrogen receptor binding
GO:0045295  gamma-catenin binding
GO:0042393  histone binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding