MAD homolog 2 (Drosophila)

同義遺伝子名

Mad-related protein 2, Smad 2, Madh2, SMAD 2, Mothers against decapentaplegic homolog 2, Smad2, MAD homolog 2 (Drosophila), Madr2, Mothers against DPP homolog 2, mMad2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:27.80

小脳:36.80

脳幹:-

脳梁:-

松果体:-

末梢神経:57.30

脊柱:-

網膜:32.10

目:53.20

動脈:-

静脈:-

リンパ節:21.60

末梢血:57.50

脾臓:131.70

胸腺:39.50

骨髄:12.80

脂肪:-

骨:125.20

皮膚:-

GeneChip

大脳:7.82

小脳:7.33

脳幹:-

脳梁:-

松果体:-

末梢神経:8.42

脊柱:7.23

網膜:7.51

目:7.57

動脈:-

静脈:8.41

リンパ節:8.88

末梢血:-

脾臓:8.83

胸腺:-

骨髄:8.73

脂肪:8.31

骨:8.47

皮膚:8.04

CAGE

大脳:3.09

小脳:-

脳幹:3.14

脳梁:-

松果体:-

末梢神経:-

脊柱:3.05

網膜:-

目:-

動脈:3.31

静脈:-

リンパ節:3.68

末梢血:-

脾臓:3.17

胸腺:3.53

骨髄:-

脂肪:-

骨:3.25

皮膚:3.53

RNA-seq

大脳:3.99

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:138.10

前立腺:30.90

卵巣:91.90

精巣:36.90

心臓:93

骨格筋:35.50

食道:-

胃:-

腸:-

結腸:17.60

肝臓:9.10

肺:120.50

膀胱:-

腎臓:24.20

下垂体:219.60

甲状腺:224.90

副腎:424.40

膵臓:18.80

乳腺:39.20

唾液腺:-

GeneChip

子宮:8.25

胎盤:9.59

前立腺:8.10

卵巣:8.39

精巣:7.97

心臓:7.67

骨格筋:7.70

食道:-

胃:8.35

腸:8.35

結腸:-

肝臓:7.67

肺:8.36

膀胱:9.17

腎臓:8.09

下垂体:8.16

甲状腺:-

副腎:7.46

膵臓:7.50

乳腺:8.08

唾液腺:6.93

CAGE

子宮:3.32

胎盤:3.55

前立腺:3.02

卵巣:3.49

精巣:3.00

心臓:-

骨格筋:-

食道:-

胃:2.85

腸:3.09

結腸:3.27

肝臓:2.98

肺:3.32

膀胱:3.90

腎臓:-

下垂体:3.30

甲状腺:-

副腎:3.54

膵臓:2.03

乳腺:3.07

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.02

食道:-

胃:-

腸:-

結腸:-

肝臓:2.87

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010754
Gene ID	17126
Unigene ID	Mm.391091
Probe set ID	1420634_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024563

オーソログ対応遺伝子

ヒト[18]	NM_001003652, NM_001135937, NM_005901
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR003619	MAD homology 1, Dwarfin-type
IPR013019	MAD homology, MH1
IPR001132	SMAD domain, Dwarfin-type
IPR017855	SMAD domain-like
IPR008984	SMAD/FHA domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0032924	activin receptor signaling pathway
GO:0009952	anterior/posterior pattern formation
GO:0045165	cell fate commitment
GO:0007182	common-partner SMAD protein phosphorylation
GO:0048589	developmental growth
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048617	embryonic foregut morphogenesis
GO:0009880	embryonic pattern specification
GO:0007492	endoderm development
GO:0001706	endoderm formation
GO:0007369	gastrulation
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0030073	insulin secretion
GO:0030324	lung development
GO:0001707	mesoderm formation
GO:0008285	negative regulation of cell proliferation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0035265	organ growth
GO:0060021	palate development
GO:0031016	pancreas development
GO:0048340	paraxial mesoderm morphogenesis
GO:0007389	pattern specification process
GO:0060039	pericardium development
GO:0030513	positive regulation of BMP signaling pathway
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0006468	protein amino acid phosphorylation
GO:0051098	regulation of binding
GO:0006355	regulation of transcription, DNA-dependent
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
GO:0070723	response to cholesterol
GO:0009749	response to glucose stimulus
GO:0007183	SMAD protein complex assembly
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007352	zygotic determination of dorsal/ventral axis

Cellular Component

GO:0032444	activin responsive factor complex
GO:0005737	cytoplasm
GO:0005622	intracellular
GO:0005634	nucleus
GO:0043234	protein complex
GO:0071141	SMAD protein complex
GO:0005667	transcription factor complex

Molecular Function

GO:0003682	chromatin binding
GO:0070410	co-SMAD binding
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0070411	I-SMAD binding
GO:0046872	metal ion binding
GO:0019902	phosphatase binding
GO:0005515	protein binding
GO:0070412	R-SMAD binding
GO:0046332	SMAD binding
GO:0033613	transcription activator binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0005160	transforming growth factor beta receptor binding
GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0034713	type I transforming growth factor beta receptor binding
GO:0031625	ubiquitin protein ligase binding

MAD homolog 2 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function