MAD homolog 7 (Drosophila)

同義遺伝子名

SMAD 7, Smad7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 7, MAD homolog 7 (Drosophila), Madh7, Madh8

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:6.90

小脳:36.80

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:64.30

目:7.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:7.90

GeneChip

大脳:7.80

小脳:7.68

脳幹:-

脳梁:-

松果体:-

末梢神経:6.60

脊柱:8.71

網膜:7.28

目:7.27

動脈:-

静脈:7.87

リンパ節:8.27

末梢血:-

脾臓:8.29

胸腺:-

骨髄:6.78

脂肪:7.13

骨:7.07

皮膚:6.66

CAGE

大脳:3.30

小脳:-

脳幹:3.73

脳梁:-

松果体:-

末梢神経:-

脊柱:4.06

網膜:-

目:-

動脈:3.45

静脈:-

リンパ節:3.30

末梢血:-

脾臓:2.61

胸腺:2.29

骨髄:-

脂肪:-

骨:2.97

皮膚:3.74

RNA-seq

大脳:1.63

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:41.40

前立腺:30.90

卵巣:11.50

精巣:236.50

心臓:37.20

骨格筋:-

食道:-

胃:32.70

腸:-

結腸:17.60

肝臓:-

肺:30.10

膀胱:66.20

腎臓:24.20

下垂体:374.60

甲状腺:-

副腎:-

膵臓:197

乳腺:13.10

唾液腺:-

GeneChip

子宮:7.61

胎盤:8.72

前立腺:7.50

卵巣:7.58

精巣:6.49

心臓:8.04

骨格筋:7.33

食道:-

胃:8.34

腸:8.46

結腸:-

肝臓:7.19

肺:9.49

膀胱:7.88

腎臓:7.93

下垂体:7.43

甲状腺:-

副腎:7.25

膵臓:6.92

乳腺:7.35

唾液腺:6.87

CAGE

子宮:3.66

胎盤:4.38

前立腺:3.80

卵巣:3.22

精巣:0.99

心臓:-

骨格筋:-

食道:-

胃:3.98

腸:3.70

結腸:4.34

肝臓:3.45

肺:4.49

膀胱:3.48

腎臓:-

下垂体:2.89

甲状腺:-

副腎:3.30

膵臓:3.83

乳腺:3.00

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.58

食道:-

胃:-

腸:-

結腸:-

肝臓:2.89

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001042660
Gene ID	17131
Unigene ID	Mm.344071
Probe set ID	1423389_at [Mouse430_2]
Ensembl ID	ENSMUSG00000025880

オーソログ対応遺伝子

ヒト[1]	NM_001190821, NM_001190822, NM_001190823, NM_005904
ラット[1]	NM_030858, NM_001190822, NM_001190823, NM_005904

染色体

遺伝子ファミリー (Interpro ID)

IPR003619	MAD homology 1, Dwarfin-type
IPR013019	MAD homology, MH1
IPR001132	SMAD domain, Dwarfin-type
IPR017855	SMAD domain-like
IPR008984	SMAD/FHA domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0034333	adherens junction assembly
GO:0048844	artery morphogenesis
GO:0034629	cellular protein complex localization
GO:0030514	negative regulation of BMP signaling pathway
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0033137	negative regulation of peptidyl-serine phosphorylation
GO:0010801	negative regulation of peptidyl-threonine phosphorylation
GO:0031397	negative regulation of protein ubiquitination
GO:0010944	negative regulation of transcription by competitive promoter binding
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0051444	negative regulation of ubiquitin-protein ligase activity
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0022409	positive regulation of cell-cell adhesion
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398	positive regulation of protein ubiquitination
GO:0050821	protein stabilization
GO:0032925	regulation of activin receptor signaling pathway
GO:0055117	regulation of cardiac muscle contraction
GO:0006355	regulation of transcription, DNA-dependent
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
GO:0060373	regulation of ventricular cardiomyocyte membrane depolarization
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0055010	ventricular cardiac muscle tissue morphogenesis
GO:0060412	ventricular septum morphogenesis

Cellular Component

GO:0016342	catenin complex
GO:0005913	cell-cell adherens junction
GO:0005737	cytoplasm
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0005667	transcription factor complex

Molecular Function

GO:0048185	activin binding
GO:0008013	beta-catenin binding
GO:0005518	collagen binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0070411	I-SMAD binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0003700	transcription factor activity
GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
GO:0034713	type I transforming growth factor beta receptor binding
GO:0031625	ubiquitin protein ligase binding

MAD homolog 7 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function