transformed mouse 3T3 cell double minute 2

詳細情報を見る

同義遺伝子名

p53-binding protein Mdm2, Ubiquitin-protein ligase E3 Mdm2, 1700007J15Rik, AA415488, Double minute 2 protein, Mdm-2, Oncoprotein Mdm2, transformed mouse 3T3 cell double minute 2, Mdm2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:9.01 小脳:9.10 脳幹:- 脳梁:- 松果体:- 末梢神経:8.69 脊柱:9.11 網膜:8.07 目:8.49 動脈:- 静脈:8.96 リンパ節:9.56 末梢血:- 脾臓:9.44 胸腺:- 骨髄:9.50 脂肪:8.77 骨:9.44 皮膚:9.29
CAGE 大脳:3.63 小脳:- 脳幹:3.43 脳梁:- 松果体:- 末梢神経:- 脊柱:3.63 網膜:- 目:- 動脈:3.63 静脈:- リンパ節:4.43 末梢血:- 脾臓:3.66 胸腺:4.24 骨髄:- 脂肪:- 骨:4.10 皮膚:3.78
RNA-seq 大脳:3.82 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:- 唾液腺:-
GeneChip 子宮:9.17 胎盤:10.11 前立腺:9.42 卵巣:9.37 精巣:10.27 心臓:8.93 骨格筋:9.43 食道:- 胃:8.77 腸:9.21 結腸:- 肝臓:8.70 肺:9.49 膀胱:9.14 腎臓:9.09 下垂体:9.45 甲状腺:- 副腎:9.26 膵臓:8.71 乳腺:9.11 唾液腺:8.18
CAGE 子宮:3.35 胎盤:4.06 前立腺:3.97 卵巣:3.62 精巣:5.68 心臓:- 骨格筋:- 食道:- 胃:3.54 腸:3.71 結腸:3.77     肝臓:3.41    肺:3.91 膀胱:3.58 腎臓:- 下垂体:3.88 甲状腺:- 副腎:3.77 膵臓:3.71 乳腺:3.44 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.49 食道:- 胃:- 腸:- 結腸:-     肝臓:3.11        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010786
Gene ID 17246
Unigene ID Mm.447669
Probe set ID 1423605_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020184

オーソログ対応遺伝子

ヒト[4]  NM_002392
ラット[3]  NM_001108099

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1535557
1552940
1614537
2026149
3474784
7472488
7477326
7477327
7651732
7671812
7849395
7936657
7958853
8058315
8152809
8247544
8440237
8449492
8660994
8674108
8812413
8838799
8889548
8895579
8917101
8943068
9087426
9126384
9144426
9153395
9153396
9171369
9241268
9285554
9294611
9380404
9419352
9486848
9632782
9651526
9653180
9843989
9861017
10050879
10065155
10075719
10077639
10099828
10205143
10321734
10341712
10349636
10365438
10419603
10436023
10523842
10597303
10611322
10706102
10713175
10721693
10754200
10822382
10906133
10921903
10922068
10982879
10995391
11013216
11042159
11076861
11100897
11172041
11217851
11245988
11335127
11423996
11431694
11528400
11588219
11606464
11697899
11718560
11857802
11857803
11861407
11948180
11953423
11983168
12032854
12080472
12115603
12138177
12145204
12154087
12162806
12167164
12167711
12232053
12297306
12466851
12477932
12488444
12493762
12509446
12520002
12529324
12547516
12556559
12606552
12628936
12702724
12730202
12754350
12832478
12904583
12927808
12944468
14522887
14555234
14610273
14610316
14612455
14673154
14691545
14695178
14729946
14767071
14769800
15024700
15029243
15090541
15102471
15144954
15162501
15172967
15195100
15242646
15306695
15361844
15364927
15467748
15485902
15577914
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15607981
15618518
15619621
15678128
15703839
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15747579
15750633
15878778
15878855
15897463
15989966
16018998
16022282
16027727
16055726
16107883
16122802
16129783
16141072
16141073
16199867
16354690
16391230
16491126
16492743
16492744
16533949
16543935
16579792
16616333
16624822
16702947
16729027
16737965
16884701
17006543
17018606
17086174
17105817
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17116689
17157790
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17245556
17329361
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17406677
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17476283
17526734
17591690
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17823617
17828300
17893884
17896003
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18204439
18206965
18287559
18309296
18317451
18359851
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18483220
18498130
18541670
18566590
18567799
18614532
18636077
18665269
18695251
18723444
18799693
18923161
19032150
19033443
19090619
19132120
19151705
19247369
19321440
19372219
19380490
19447627
19491200
19521340
19536131
19541625
19580521
19590512
19630168
19649205
19732750
19833129
19842060
19950214
19965665
20019182
20124454
20362536
20386595
20478998
20542919
20588255
20592017
20598683
20619429
20639885
20657550
20671749
20697359
20818388
20832750
20832751
20849854
20855528
20921405
21040902
21060154
21081496
21169420
21183956
21211512
21213101
21267068
21285512
21317535
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21402876
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22998186
23029416
23115126
23149414
23251530
23260144
23333058
23401854
23580573
23682023
23749457
23770245
23935987
23973961
24013501
24167073
24440154

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0045184  establishment of protein localization
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0071157  negative regulation of cell cycle arrest
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0010629  negative regulation of gene expression
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0018205  peptidyl-lysine modification
GO:0045787  positive regulation of cell cycle
GO:0010628  positive regulation of gene expression
GO:0045931  positive regulation of mitotic cell cycle
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0046827  positive regulation of protein export from nucleus
GO:0030163  protein catabolic process
GO:0006461  protein complex assembly
GO:0031648  protein destabilization
GO:0034504  protein localization in nucleus
GO:0016567  protein ubiquitination
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0042176  regulation of protein catabolic process
GO:0007089  traversing start control point of mitotic cell cycle

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0045202  synapse

Molecular Function

GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0016874  ligase activity
GO:0046872  metal ion binding
GO:0002039  p53 binding
GO:0042975  peroxisome proliferator activated receptor binding
GO:0005515  protein binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding