myocyte enhancer factor 2C

詳細情報を見る

同義遺伝子名

AV011172, Myocyte-specific enhancer factor 2C, myocyte enhancer factor 2C, 9930028G15Rik, Mef2c, 5430401D19Rik

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:246.60 小脳:110.50 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:96.40 目:76 動脈:- 静脈:- リンパ節:10.80 末梢血:115 脾臓:210.70 胸腺:9.90 骨髄:12.80 脂肪:- 骨:112.70 皮膚:63.30
GeneChip 大脳:10.43 小脳:7.45 脳幹:- 脳梁:- 松果体:- 末梢神経:7.79 脊柱:6.59 網膜:9.21 目:6.01 動脈:- 静脈:8.27 リンパ節:10.23 末梢血:- 脾臓:10.18 胸腺:- 骨髄:8.62 脂肪:8.40 骨:9.66 皮膚:9.13
CAGE 大脳:4.45 小脳:- 脳幹:4.13 脳梁:- 松果体:- 末梢神経:- 脊柱:3.48 網膜:- 目:- 動脈:4.62 静脈:- リンパ節:6.51 末梢血:- 脾臓:4.83 胸腺:2.86 骨髄:- 脂肪:- 骨:4.90 皮膚:4.76
RNA-seq 大脳:9.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:37.20 骨格筋:106.50 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:20.10    膀胱:- 腎臓:8.10 下垂体:25.80 甲状腺:- 副腎:- 膵臓:56.30 乳腺:3.30 唾液腺:-
GeneChip 子宮:7.61 胎盤:5.29 前立腺:7.93 卵巣:8.16 精巣:5.51 心臓:8.95 骨格筋:11.79 食道:- 胃:5.79 腸:6.32 結腸:- 肝臓:4.55 肺:7.59 膀胱:7.81 腎臓:6.03 下垂体:6.02 甲状腺:- 副腎:8.80 膵臓:7.30 乳腺:9.48 唾液腺:6.97
CAGE 子宮:3.92 胎盤:2.73 前立腺:2.43 卵巣:3.97 精巣:1.60 心臓:- 骨格筋:- 食道:- 胃:2.79 腸:2.67 結腸:3.08     肝臓:2.23    肺:4.40 膀胱:3.85 腎臓:- 下垂体:2.87 甲状腺:- 副腎:4.25 膵臓:2.83 乳腺:3.45 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:23.62 食道:- 胃:- 腸:- 結腸:-     肝臓:0.86        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_025282
Gene ID 17260
Unigene ID Mm.24001
Probe set ID 1421027_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005583

オーソログ対応遺伝子

ヒト[6]  NM_001131005, NM_001193347, NM_001193348, NM_001193350, NM_002397
ラット[6]  NM_001131005, NM_001193347, NM_001193348, NM_001193350, NM_002397

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

7628699
7643214
7646512
7677753
8026334
8035824
8114702
8506376
8530078
8575763
8663403
8668199
8817457
8889548
8900141
8955271
8993831
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9268575
9436646
9500551
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9738004
9758703
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9876177
9925645
10021345
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10207130
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10395786
10531040
10625552
10675351
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10700190
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19622544
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23603510
23704920
24043307
24147056
24186978
24218567
24301466
24351932
24591619

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001782  B cell homeostasis
GO:0042100  B cell proliferation
GO:0050853  B cell receptor signaling pathway
GO:0001568  blood vessel development
GO:0001974  blood vessel remodeling
GO:0035051  cardiac cell differentiation
GO:0055007  cardiac muscle cell differentiation
GO:0014898  cardiac muscle hypertrophy in response to stress
GO:0003211  cardiac ventricle formation
GO:0060536  cartilage morphogenesis
GO:0030154  cell differentiation
GO:0045165  cell fate commitment
GO:0071277  cellular response to calcium ion
GO:0071498  cellular response to fluid shear stress
GO:0071363  cellular response to growth factor stimulus
GO:0071222  cellular response to lipopolysaccharide
GO:0071374  cellular response to parathyroid hormone stimulus
GO:0071300  cellular response to retinoic acid
GO:0002062  chondrocyte differentiation
GO:0048704  embryonic skeletal system morphogenesis
GO:0048703  embryonic viscerocranium morphogenesis
GO:0001958  endochondral ossification
GO:0002467  germinal center formation
GO:0007507  heart development
GO:0001947  heart looping
GO:0006959  humoral immune response
GO:0007611  learning or memory
GO:0000165  MAPKKK cascade
GO:0030318  melanocyte differentiation
GO:0030224  monocyte differentiation
GO:0007275  multicellular organismal development
GO:0007521  muscle cell fate determination
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010629  negative regulation of gene expression
GO:0043524  negative regulation of neuron apoptosis
GO:0030279  negative regulation of ossification
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007399  nervous system development
GO:0014033  neural crest cell differentiation
GO:0048666  neuron development
GO:0030182  neuron differentiation
GO:0001649  osteoblast differentiation
GO:0003151  outflow tract morphogenesis
GO:0060021  palate development
GO:0030220  platelet formation
GO:0010694  positive regulation of alkaline phosphatase activity
GO:0030890  positive regulation of B cell proliferation
GO:0030501  positive regulation of bone mineralization
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0010628  positive regulation of gene expression
GO:0045663  positive regulation of myoblast differentiation
GO:0045666  positive regulation of neuron differentiation
GO:0045669  positive regulation of osteoblast differentiation
GO:0090073  positive regulation of protein homodimerization activity
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0003138  primary heart field specification
GO:0002634  regulation of germinal center formation
GO:0045652  regulation of megakaryocyte differentiation
GO:0060297  regulation of sarcomere organization
GO:0060025  regulation of synaptic activity
GO:0006355  regulation of transcription, DNA-dependent
GO:0003139  secondary heart field specification
GO:0003185  sinoatrial valve morphogenesis
GO:0007519  skeletal muscle tissue development
GO:0051145  smooth muscle cell differentiation
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0055012  ventricular cardiac muscle cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0016607  nuclear speck
GO:0005634  nucleus
GO:0043234  protein complex
GO:0030017  sarcomere

Molecular Function

GO:0003680  AT DNA binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0042826  histone deacetylase binding
GO:0035198  miRNA binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0033613  transcription activator binding
GO:0003700  transcription factor activity