myocyte enhancer factor 2C

詳細情報を見る

同義遺伝子名

AV011172, Myocyte-specific enhancer factor 2C, myocyte enhancer factor 2C, 9930028G15Rik, Mef2c, 5430401D19Rik

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:17.40 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:32.10 目:7.60 動脈:- 静脈:- リンパ節:10.80 末梢血:43.10 脾臓:39.50 胸腺:9.90 骨髄:- 脂肪:- 骨:- 皮膚:15.80
GeneChip 大脳:9.22 小脳:6.52 脳幹:- 脳梁:- 松果体:- 末梢神経:6.29 脊柱:5.91 網膜:7.43 目:5.51 動脈:- 静脈:7.08 リンパ節:8.96 末梢血:- 脾臓:8.95 胸腺:- 骨髄:7.28 脂肪:7.32 骨:7.97 皮膚:7.54
CAGE 大脳:4.45 小脳:- 脳幹:4.13 脳梁:- 松果体:- 末梢神経:- 脊柱:3.48 網膜:- 目:- 動脈:4.62 静脈:- リンパ節:6.51 末梢血:- 脾臓:4.83 胸腺:2.86 骨髄:- 脂肪:- 骨:4.90 皮膚:4.76
RNA-seq 大脳:9.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:7.40 心臓:18.60 骨格筋:177.50 食道:- 胃:- 腸:- 結腸:-     肝臓:18.10        肺:10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:28.10 乳腺:3.30 唾液腺:54
GeneChip 子宮:6.14 胎盤:5.26 前立腺:6.64 卵巣:6.58 精巣:5.66 心臓:7.09 骨格筋:10.51 食道:- 胃:5.42 腸:5.50 結腸:- 肝臓:4.91 肺:6.28 膀胱:6.58 腎臓:5.34 下垂体:5.21 甲状腺:- 副腎:6.72 膵臓:6.49 乳腺:8.40 唾液腺:5.38
CAGE 子宮:3.92 胎盤:2.73 前立腺:2.43 卵巣:3.97 精巣:1.60 心臓:- 骨格筋:- 食道:- 胃:2.79 腸:2.67 結腸:3.08     肝臓:2.23    肺:4.40 膀胱:3.85 腎臓:- 下垂体:2.87 甲状腺:- 副腎:4.25 膵臓:2.83 乳腺:3.45 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:23.62 食道:- 胃:- 腸:- 結腸:-     肝臓:0.86        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_025282
Gene ID 17260
Unigene ID Mm.392364
Probe set ID 1421028_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005583

オーソログ対応遺伝子

ヒト[6]  NM_001131005, NM_001193347, NM_001193348, NM_001193350, NM_002397
ラット[6]  NM_001131005, NM_001193347, NM_001193348, NM_001193350, NM_002397

染色体

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遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7628699
7643214
7646512
7677753
8026334
8035824
8114702
8506376
8530078
8575763
8663403
8668199
8817457
8889548
8900141
8955271
8993831
9013788
9162005
9188042
9268575
9436646
9500551
9621431
9738004
9758703
9778514
9876177
9925645
10021345
10075840
10207130
10322110
10349636
10395786
10531040
10625552
10675351
10694423
10700190
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10926756
10983972
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11554755
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19622544
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20181743
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23468913
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23603510
23704920
24043307
24147056
24186978
24218567
24301466
24351932
24591619

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001782  B cell homeostasis
GO:0042100  B cell proliferation
GO:0050853  B cell receptor signaling pathway
GO:0001568  blood vessel development
GO:0001974  blood vessel remodeling
GO:0035051  cardiac cell differentiation
GO:0055007  cardiac muscle cell differentiation
GO:0014898  cardiac muscle hypertrophy in response to stress
GO:0003211  cardiac ventricle formation
GO:0060536  cartilage morphogenesis
GO:0030154  cell differentiation
GO:0045165  cell fate commitment
GO:0071277  cellular response to calcium ion
GO:0071498  cellular response to fluid shear stress
GO:0071363  cellular response to growth factor stimulus
GO:0071222  cellular response to lipopolysaccharide
GO:0071374  cellular response to parathyroid hormone stimulus
GO:0071300  cellular response to retinoic acid
GO:0002062  chondrocyte differentiation
GO:0048704  embryonic skeletal system morphogenesis
GO:0048703  embryonic viscerocranium morphogenesis
GO:0001958  endochondral ossification
GO:0002467  germinal center formation
GO:0007507  heart development
GO:0001947  heart looping
GO:0006959  humoral immune response
GO:0007611  learning or memory
GO:0000165  MAPKKK cascade
GO:0030318  melanocyte differentiation
GO:0030224  monocyte differentiation
GO:0007275  multicellular organismal development
GO:0007521  muscle cell fate determination
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010629  negative regulation of gene expression
GO:0043524  negative regulation of neuron apoptosis
GO:0030279  negative regulation of ossification
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007399  nervous system development
GO:0014033  neural crest cell differentiation
GO:0048666  neuron development
GO:0030182  neuron differentiation
GO:0001649  osteoblast differentiation
GO:0003151  outflow tract morphogenesis
GO:0060021  palate development
GO:0030220  platelet formation
GO:0010694  positive regulation of alkaline phosphatase activity
GO:0030890  positive regulation of B cell proliferation
GO:0030501  positive regulation of bone mineralization
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0010628  positive regulation of gene expression
GO:0045663  positive regulation of myoblast differentiation
GO:0045666  positive regulation of neuron differentiation
GO:0045669  positive regulation of osteoblast differentiation
GO:0090073  positive regulation of protein homodimerization activity
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0003138  primary heart field specification
GO:0002634  regulation of germinal center formation
GO:0045652  regulation of megakaryocyte differentiation
GO:0060297  regulation of sarcomere organization
GO:0060025  regulation of synaptic activity
GO:0006355  regulation of transcription, DNA-dependent
GO:0003139  secondary heart field specification
GO:0003185  sinoatrial valve morphogenesis
GO:0007519  skeletal muscle tissue development
GO:0051145  smooth muscle cell differentiation
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0055012  ventricular cardiac muscle cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0016607  nuclear speck
GO:0005634  nucleus
GO:0043234  protein complex
GO:0030017  sarcomere

Molecular Function

GO:0003680  AT DNA binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0042826  histone deacetylase binding
GO:0035198  miRNA binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0033613  transcription activator binding
GO:0003700  transcription factor activity