neurofibromatosis 1

同義遺伝子名

E030030H24Rik, neurofibromin, Neurofibromin, Nf1, neurofibromatosis 1, AW494271, Nf-1, Neurofibromatosis-related protein NF-1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:52.10

小脳:55.30

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:45.60

動脈:84.40

静脈:-

リンパ節:32.40

末梢血:14.40

脾臓:13.20

胸腺:19.80

骨髄:-

脂肪:-

骨:12.50

皮膚:31.70

GeneChip

大脳:4.42

小脳:4.46

脳幹:-

脳梁:-

松果体:-

末梢神経:4.50

脊柱:4.67

網膜:4.16

目:4.33

動脈:-

静脈:4.43

リンパ節:4.14

末梢血:-

脾臓:4.27

胸腺:-

骨髄:4.10

脂肪:4.23

骨:4.09

皮膚:4.16

CAGE

大脳:4.44

小脳:-

脳幹:4.64

脳梁:-

松果体:-

末梢神経:-

脊柱:4.77

網膜:-

目:-

動脈:3.92

静脈:-

リンパ節:3.73

末梢血:-

脾臓:2.83

胸腺:3.14

骨髄:-

脂肪:-

骨:3.02

皮膚:3.98

RNA-seq

大脳:2.63

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:30.90

卵巣:11.50

精巣:14.80

心臓:37.20

骨格筋:-

食道:-

胃:-

腸:37

結腸:-

肝臓:-

肺:50.20

膀胱:198.50

腎臓:32.20

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:26.10

唾液腺:-

GeneChip

子宮:4.29

胎盤:4.34

前立腺:4

卵巣:4.47

精巣:4.53

心臓:4.66

骨格筋:4.34

食道:-

胃:4.20

腸:4.30

結腸:-

肝臓:4.74

肺:4.18

膀胱:4.38

腎臓:4.38

下垂体:4.08

甲状腺:-

副腎:4.47

膵臓:4.49

乳腺:4.38

唾液腺:4.08

CAGE

子宮:3.71

胎盤:2.89

前立腺:4.00

卵巣:3.83

精巣:4.73

心臓:-

骨格筋:-

食道:-

胃:2.44

腸:3.42

結腸:3.68

肝臓:3.20

肺:3.76

膀胱:3.77

腎臓:-

下垂体:4.02

甲状腺:-

副腎:3.86

膵臓:3.64

乳腺:3.52

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.76

食道:-

胃:-

腸:-

結腸:-

肝臓:1.98

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010897
Gene ID	18015
Unigene ID	Mm.255596
Probe set ID	1452525_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000020716

オーソログ対応遺伝子

ヒト[14]	NM_000267, NM_001042492, NM_001128147
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR001936	Ras GTPase-activating protein
IPR008936	Rho GTPase activation protein

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0030325	adrenal gland development
GO:0048844	artery morphogenesis
GO:0007420	brain development
GO:0048593	camera-type eye morphogenesis
GO:0007154	cell communication
GO:0021987	cerebral cortex development
GO:0050890	cognition
GO:0030199	collagen fibril organization
GO:0030198	extracellular matrix organization
GO:0021897	forebrain astrocyte development
GO:0048853	forebrain morphogenesis
GO:0007507	heart development
GO:0008625	induction of apoptosis via death domain receptors
GO:0001889	liver development
GO:0000165	MAPKKK cascade
GO:0001656	metanephros development
GO:0022011	myelination in the peripheral nervous system
GO:0016525	negative regulation of angiogenesis
GO:0048712	negative regulation of astrocyte differentiation
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0001953	negative regulation of cell-matrix adhesion
GO:0001937	negative regulation of endothelial cell proliferation
GO:0048147	negative regulation of fibroblast proliferation
GO:0043407	negative regulation of MAP kinase activity
GO:0043409	negative regulation of MAPKKK cascade
GO:0007406	negative regulation of neuroblast proliferation
GO:0046929	negative regulation of neurotransmitter secretion
GO:0048715	negative regulation of oligodendrocyte differentiation
GO:0045671	negative regulation of osteoclast differentiation
GO:0006469	negative regulation of protein kinase activity
GO:0035021	negative regulation of Rac protein signal transduction
GO:0046580	negative regulation of Ras protein signal transduction
GO:0042992	negative regulation of transcription factor import into nucleus
GO:0021915	neural tube development
GO:0001649	osteoblast differentiation
GO:0007422	peripheral nervous system development
GO:0014065	phosphoinositide 3-kinase cascade
GO:0043473	pigmentation
GO:0045762	positive regulation of adenylate cyclase activity
GO:0043065	positive regulation of apoptosis
GO:0001938	positive regulation of endothelial cell proliferation
GO:0043525	positive regulation of neuron apoptosis
GO:0032320	positive regulation of Ras GTPase activity
GO:0007265	Ras protein signal transduction
GO:0045765	regulation of angiogenesis
GO:0043535	regulation of blood vessel endothelial cell migration
GO:0045124	regulation of bone resorption
GO:0042127	regulation of cell proliferation
GO:0001952	regulation of cell-matrix adhesion
GO:0045685	regulation of glial cell differentiation
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0045664	regulation of neuron differentiation
GO:0032318	regulation of Ras GTPase activity
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0032228	regulation of synaptic transmission, GABAergic
GO:0001666	response to hypoxia
GO:0014044	Schwann cell development
GO:0007165	signal transduction
GO:0007519	skeletal muscle tissue development
GO:0048745	smooth muscle tissue development
GO:0021510	spinal cord development
GO:0048485	sympathetic nervous system development
GO:0008542	visual learning
GO:0042060	wound healing

Cellular Component

GO:0030424	axon
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0005622	intracellular
GO:0031235	intrinsic to internal side of plasma membrane
GO:0016020	membrane
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0014069	postsynaptic density
GO:0043234	protein complex

Molecular Function

GO:0005096	GTPase activator activity
GO:0008017	microtubule binding
GO:0005515	protein binding
GO:0005099	Ras GTPase activator activity
GO:0045545	syndecan binding

neurofibromatosis 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function