nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

詳細情報を見る

同義遺伝子名

Nfkbia, I-kappa-B-alpha, Ikba, NF-kappa-B inhibitor alpha, IKB-alpha, I(Kappa)B(alpha), Nfkbi, IkappaBalpha, AI462015

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:24.30 小脳:18.40 脳幹:31.80 脳梁:- 松果体:515.60 末梢神経:38.20 脊柱:- 網膜:32.10 目:- 動脈:- 静脈:- リンパ節:43.20 末梢血:143.80 脾臓:92.20 胸腺:168 骨髄:333.40 脂肪:- 骨:150.30 皮膚:23.80
GeneChip 大脳:10.61 小脳:10.84 脳幹:- 脳梁:- 松果体:- 末梢神経:10.80 脊柱:10.91 網膜:11.14 目:11.68 動脈:- 静脈:12.14 リンパ節:13.02 末梢血:- 脾臓:12.90 胸腺:- 骨髄:12.28 脂肪:11.71 骨:12.54 皮膚:12.96
CAGE 大脳:3.09 小脳:- 脳幹:3.35 脳梁:- 松果体:- 末梢神経:- 脊柱:3.57 網膜:- 目:- 動脈:4.32 静脈:- リンパ節:5.03 末梢血:- 脾臓:4.32 胸腺:5.15 骨髄:- 脂肪:- 骨:4.40 皮膚:4.55
RNA-seq 大脳:5.97 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:96.70 前立腺:92.60 卵巣:34.50 精巣:59.10 心臓:18.60 骨格筋:106.50 食道:- 胃:654.60 腸:1331 結腸:264.30     肝臓:36.20        肺:100.40    膀胱:- 腎臓:48.40 下垂体:12.90 甲状腺:224.90 副腎:- 膵臓:84.40 乳腺:143.70 唾液腺:-
GeneChip 子宮:12.16 胎盤:11.65 前立腺:11.27 卵巣:11.70 精巣:9.41 心臓:11.71 骨格筋:10.58 食道:- 胃:11.68 腸:12.07 結腸:- 肝臓:11.31 肺:12.88 膀胱:11.80 腎臓:10.65 下垂体:11.66 甲状腺:- 副腎:12.78 膵臓:10.68 乳腺:12.56 唾液腺:12.11
CAGE 子宮:5.32 胎盤:4.00 前立腺:4.02 卵巣:4.08 精巣:3.23 心臓:- 骨格筋:- 食道:- 胃:4.40 腸:3.84 結腸:4.72     肝臓:4.35    肺:4.98 膀胱:3.92 腎臓:- 下垂体:4.10 甲状腺:- 副腎:4.49 膵臓:3.83 乳腺:4.88 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:6.49 食道:- 胃:- 腸:- 結腸:-     肝臓:9.17        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010907
Gene ID 18035
Unigene ID Mm.170515
Probe set ID 1420088_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021025

オーソログ対応遺伝子

ヒト[1]  NM_020529
ラット[2]  NM_001105720

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

1339305
1740450
7552992
7590249
7603567
7867065
7936653
7963540
8628301
8642348
8662753
8858144
8864120
8887559
8914937
9186501
9597130
9743524
9854797
10097128
10195896
10199915
10349636
10702415
10748240
10922068
11009421
11042159
11067893
11076861
11130978
11133232
11179036
11217851
11221845
11241200
11359934
11799106
11880364
11896578
11913973
12083419
12167702
12397017
12424381
12466851
12477932
12589049
12626571
12843402
12872135
12896983
12920239
12938156
14585967
14610273
14665694
14676146
14741691
14763901
14764534
14767066
14960276
14966265
14978074
14991073
15020231
15071597
15102471
15161102
15251865
15294950
15317747
15479644
15489334
15536134
15618518
15671248
15692051
15714207
15811852
15820254
15845452
15858576
15879100
15923614
15989949
15998793
16141072
16141073
16163708
16166517
16199483
16231352
16260626
16371367
16452166
16481354
16648481
16737960
16804897
16928772
16931600
17098744
17158449
17202411
17237376
17254973
17307728
17310217
17392377
17486138
17692539
17878344
18056349
18070894
18194271
18233957
18233961
18261938
18287559
18321726
18378686
18395765
18401342
18505784
18544347
18566250
18604869
18676814
18701501
18981184
19091594
19098124
19299176
19349372
19487661
19524538
19614983
19672210
19796012
19890047
19931640
19933270
20020511
20153290
20211142
20385620
20412781
20581820
20634424
20661182
20661281
20663042
20682784
20696914
20797629
20811394
21098220
21152039
21156791
21176770
21267068
21333553
21411734
21439970
21454528
21606193
21617130
21632113
21658309
21677750
21706061
21737317
21765415
21814576
21862579
21874024
22037600
22134901
22203995
22318993
22402282
22445657
22633953
22761574
23041330
23086447
23172686
23262141
23431057
23435124
23776228
23850221
23951545
24176090

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007253  cytoplasmic sequestering of NF-kappaB
GO:0042994  cytoplasmic sequestering of transcription factor
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0010888  negative regulation of lipid storage
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0045638  negative regulation of myeloid cell differentiation
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0045746  negative regulation of Notch signaling pathway
GO:0070427  nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431  nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010875  positive regulation of cholesterol efflux
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0000060  protein import into nucleus, translocation
GO:0042127  regulation of cell proliferation
GO:0043330  response to exogenous dsRNA
GO:0032496  response to lipopolysaccharide
GO:0032495  response to muramyl dipeptide
GO:0034142  toll-like receptor 4 signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0019899  enzyme binding
GO:0031072  heat shock protein binding
GO:0042802  identical protein binding
GO:0051059  NF-kappaB binding
GO:0008139  nuclear localization sequence binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0031625  ubiquitin protein ligase binding