nerve growth factor receptor (TNFR superfamily, member 16)

詳細情報を見る

同義遺伝子名

p75, LNGFR, p75NTR, p75 neurotrophin receptor, Low affinity neurotrophin receptor p75NTR, Tnfrsf16, p75NGFR, Ngfr, Low-affinity nerve growth factor receptor, NGF receptor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:191.10 脊柱:- 網膜:- 目:45.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:52.70 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:39.60
GeneChip 大脳:4.37 小脳:4.45 脳幹:- 脳梁:- 松果体:- 末梢神経:8.95 脊柱:4.57 網膜:4.38 目:4.78 動脈:- 静脈:4.51 リンパ節:4.87 末梢血:- 脾臓:4.54 胸腺:- 骨髄:4.40 脂肪:4.48 骨:4.13 皮膚:4.71
CAGE 大脳:0.62 小脳:- 脳幹:1.47 脳梁:- 松果体:- 末梢神経:- 脊柱:1.42 網膜:- 目:- 動脈:1.15 静脈:- リンパ節:1.98 末梢血:- 脾臓:1.12 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:1.86
RNA-seq 大脳:0.97 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:50.20    膀胱:66.20 腎臓:- 下垂体:90.40 甲状腺:- 副腎:- 膵臓:28.10 乳腺:9.80 唾液腺:-
GeneChip 子宮:6.25 胎盤:4.59 前立腺:4.61 卵巣:4.84 精巣:6.32 心臓:4.85 骨格筋:4.57 食道:- 胃:4.63 腸:4.55 結腸:- 肝臓:4.98 肺:4.34 膀胱:4.50 腎臓:4.59 下垂体:4.55 甲状腺:- 副腎:4.36 膵臓:4.74 乳腺:4.41 唾液腺:4.91
CAGE 子宮:4.25 胎盤:0.27 前立腺:2.76 卵巣:2.76 精巣:0 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:1.14 結腸:1.11     肝臓:0.91    肺:0.31 膀胱:2.65 腎臓:- 下垂体:0.29 甲状腺:- 副腎:1.72 膵臓:0 乳腺:0.88 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.49 食道:- 胃:- 腸:- 結腸:-     肝臓:1.43        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_033217
Gene ID 18053
Unigene ID Mm.283893
Probe set ID 1450177_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000120

オーソログ対応遺伝子

ヒト[2]  NM_002507
ラット[2]  NM_012610

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

571871
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0030154  cell differentiation
GO:0034599  cellular response to oxidative stress
GO:0007417  central nervous system development
GO:0016048  detection of temperature stimulus
GO:0042593  glucose homeostasis
GO:0031069  hair follicle morphogenesis
GO:0006917  induction of apoptosis
GO:0006886  intracellular protein transport
GO:0007275  multicellular organismal development
GO:0060548  negative regulation of cell death
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0051799  negative regulation of hair follicle development
GO:0051902  negative regulation of mitochondrial depolarization
GO:0043524  negative regulation of neuron apoptosis
GO:0010977  negative regulation of neuron projection development
GO:0021675  nerve development
GO:0007399  nervous system development
GO:0043065  positive regulation of apoptosis
GO:0010942  positive regulation of cell death
GO:0048146  positive regulation of fibroblast proliferation
GO:0043410  positive regulation of MAPKKK cascade
GO:0031643  positive regulation of myelination
GO:0042488  positive regulation of odontogenesis of dentine-containing tooth
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0035025  positive regulation of Rho protein signal transduction
GO:0032224  positive regulation of synaptic transmission, cholinergic
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0010468  regulation of gene expression
GO:0009611  response to wounding
GO:0019233  sensory perception of pain
GO:0007165  signal transduction
GO:0043588  skin development

Cellular Component

GO:0032809  cell soma membrane
GO:0009986  cell surface
GO:0045334  clathrin-coated endocytic vesicle
GO:0030135  coated vesicle
GO:0005737  cytoplasm
GO:0032590  dendrite membrane
GO:0009897  external side of plasma membrane
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005635  nuclear envelope
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0005886  plasma membrane
GO:0005791  rough endoplasmic reticulum

Molecular Function

GO:0001540  beta-amyloid binding
GO:0005035  death receptor activity
GO:0048406  nerve growth factor binding
GO:0043121  neurotrophin binding
GO:0005168  neurotrophin TRKA receptor binding
GO:0070678  preprotein binding
GO:0005515  protein binding
GO:0017137  Rab GTPase binding
GO:0031625  ubiquitin protein ligase binding