solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

同義遺伝子名

Nramp, MGC129157, NRAMP 1, ity, host resistance locus Bcg/Ity/Lsh, Slc11a1, Lsh, Ity, Natural resistance-associated macrophage protein 1, Bcg, MGC129156, Nramp1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:9.90

骨髄:12.80

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:5.74

小脳:5.71

脳幹:-

脳梁:-

松果体:-

末梢神経:6.06

脊柱:6.20

網膜:5.99

目:7.31

動脈:-

静脈:6.93

リンパ節:8.99

末梢血:-

脾臓:9.09

胸腺:-

骨髄:8.67

脂肪:7.14

骨:8.11

皮膚:5.82

CAGE

大脳:0.84

小脳:-

脳幹:0.91

脳梁:-

松果体:-

末梢神経:-

脊柱:0.83

網膜:-

目:-

動脈:1.83

静脈:-

リンパ節:2.62

末梢血:-

脾臓:2.96

胸腺:1.17

骨髄:-

脂肪:-

骨:3.35

皮膚:1.09

RNA-seq

大脳:1.24

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:11.50

精巣:-

心臓:18.60

骨格筋:35.50

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:19.60

唾液腺:-

GeneChip

子宮:7.08

胎盤:6.07

前立腺:6.69

卵巣:6.68

精巣:5.97

心臓:6.88

骨格筋:6.80

食道:-

胃:6.50

腸:6.21

結腸:-

肝臓:7.41

肺:7.06

膀胱:6.70

腎臓:6.10

下垂体:5.79

甲状腺:-

副腎:6.88

膵臓:6.71

乳腺:6.90

唾液腺:7.16

CAGE

子宮:1.62

胎盤:1.10

前立腺:0.74

卵巣:1.79

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:2.04

腸:1.05

結腸:1.40

肝臓:2.38

肺:2.19

膀胱:1.36

腎臓:-

下垂体:1.11

甲状腺:-

副腎:2.79

膵臓:1.61

乳腺:1.66

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.42

食道:-

胃:-

腸:-

結腸:-

肝臓:1.85

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_013612
Gene ID	18173
Unigene ID	Mm.291311
Probe set ID	1420361_at [Mouse430_2]
Ensembl ID	ENSMUSG00000026177

オーソログ対応遺伝子

ヒト[4]	NM_000578
ラット[1]	NM_001031658

染色体

遺伝子ファミリー (Interpro ID)

IPR001046

Natural resistance-associated macrophage protein

遺伝子オントロジー (GO ID)

Biological Process

GO:0032147	activation of protein kinase activity
GO:0048002	antigen processing and presentation of peptide antigen
GO:0070574	cadmium ion transmembrane transport
GO:0006876	cellular cadmium ion homeostasis
GO:0006879	cellular iron ion homeostasis
GO:0042742	defense response to bacterium
GO:0050829	defense response to Gram-negative bacterium
GO:0042832	defense response to protozoan
GO:0070839	divalent metal ion export
GO:0006954	inflammatory response
GO:0032623	interleukin-2 production
GO:0032632	interleukin-3 production
GO:0006811	ion transport
GO:0055072	iron ion homeostasis
GO:0006826	iron ion transport
GO:0043091	L-arginine import
GO:0042116	macrophage activation
GO:0071421	manganese ion transmembrane transport
GO:0006828	manganese ion transport
GO:0000165	MAPKKK cascade
GO:0045342	MHC class II biosynthetic process
GO:0048255	mRNA stabilization
GO:0060586	multicellular organismal iron ion homeostasis
GO:0001818	negative regulation of cytokine production
GO:0015707	nitrite transport
GO:0006909	phagocytosis
GO:0001819	positive regulation of cytokine production
GO:0002606	positive regulation of dendritic cell antigen processing and presentation
GO:0010628	positive regulation of gene expression
GO:0032729	positive regulation of interferon-gamma production
GO:0050766	positive regulation of phagocytosis
GO:0002827	positive regulation of T-helper 1 type immune response
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0000060	protein import into nucleus, translocation
GO:0045730	respiratory burst
GO:0009617	response to bacterium
GO:0034341	response to interferon-gamma
GO:0032496	response to lipopolysaccharide
GO:0002369	T cell cytokine production
GO:0002309	T cell proliferation during immune response
GO:0006810	transport
GO:0007035	vacuolar acidification
GO:0042060	wound healing

Cellular Component

GO:0009279	cell outer membrane
GO:0009986	cell surface
GO:0010008	endosome membrane
GO:0016021	integral to membrane
GO:0005770	late endosome
GO:0005764	lysosome
GO:0016020	membrane
GO:0030670	phagocytic vesicle membrane
GO:0005886	plasma membrane
GO:0070821	tertiary granule membrane

Molecular Function

GO:0005384	manganese ion transmembrane transporter activity
GO:0051139	metal ion:hydrogen antiporter activity
GO:0042803	protein homodimerization activity
GO:0046915	transition metal ion transmembrane transporter activity
GO:0005215	transporter activity

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function