solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

 詳細情報を見る

同義遺伝子名

NRAMP 2, Slc11a2, mk, microcytic anemia, viable anaemia, Natural resistance-associated macrophage protein 2, Nramp2, DCT1, van, DMT1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:79.90 小脳:110.50 脳幹:31.80 脳梁:- 松果体:- 末梢神経:- 脊柱:94.60 網膜:96.40 目:83.60 動脈:- 静脈:- リンパ節:10.80 末梢血:- 脾臓:92.20 胸腺:98.80 骨髄:230.80 脂肪:- 骨:125.20 皮膚:213.80
GeneChip 大脳:6.42 小脳:6.59 脳幹:- 脳梁:- 松果体:- 末梢神経:6.27 脊柱:6.50 網膜:6.14 目:6.29 動脈:- 静脈:6.25 リンパ節:6.72 末梢血:- 脾臓:6.72 胸腺:- 骨髄:8.29 脂肪:7.10 骨:7.45 皮膚:6.54
CAGE 大脳:3.04 小脳:- 脳幹:3.15 脳梁:- 松果体:- 末梢神経:- 脊柱:3.24 網膜:- 目:- 動脈:3.20 静脈:- リンパ節:2.81 末梢血:- 脾臓:3.61 胸腺:2.76 骨髄:- 脂肪:- 骨:3.32 皮膚:2.87
RNA-seq 大脳:4.97 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:43.60 胎盤:138.10 前立腺:- 卵巣:149.40 精巣:14.80 心臓:130.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:9.10        肺:60.30    膀胱:66.20 腎臓:80.60 下垂体:38.80 甲状腺:- 副腎:848.90 膵臓:178.30 乳腺:101.20 唾液腺:54
GeneChip 子宮:7.06 胎盤:8.02 前立腺:7.81 卵巣:6.76 精巣:6.72 心臓:6.10 骨格筋:7.07 食道:- 胃:7.01 腸:7.11 結腸:- 肝臓:6.94 肺:6.69 膀胱:6.27 腎臓:7.75 下垂体:6.05 甲状腺:- 副腎:6.18 膵臓:6.87 乳腺:6.98 唾液腺:5.30
CAGE 子宮:3.17 胎盤:3.19 前立腺:4.55 卵巣:3.14 精巣:2.64 心臓:- 骨格筋:- 食道:- 胃:2.95 腸:3.83 結腸:3.76     肝臓:3.21    肺:3.23 膀胱:2.61 腎臓:- 下垂体:2.73 甲状腺:- 副腎:3.92 膵臓:3.36 乳腺:3.67 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.58 食道:- 胃:- 腸:- 結腸:-     肝臓:3.90        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_008732
Gene ID 18174
Unigene ID Mm.234608
Probe set ID 1452078_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000023030

オーソログ対応遺伝子

ヒト[3]  NM_000617, NM_001174125, NM_001174126, NM_001174127, NM_001174128, NM_001174129, NM_001174130
ラット [0]  

染色体

15F1  [100,218,329  -  100,255,503]

遺伝子ファミリー (Interpro ID)

IPR001046  Natural resistance-associated macrophage protein

Link to Pubmed  (Pubmed ID)

658175
782924
807277
2744761
3366378
4404581
4563452
5070129
5427253
5507573
5521744
7613023
7789986
7995373
8469289
8661115
8703126
8889548
9241278
9448300
10077651
10349636
10577506
10791995
10922068
10942769
11042159
11076861
11090085
11159549
11175792
11217851
11739192
11741608
11964145
12081573
12209011
12239176
12466851
12477932
12522007
12576298
12724326
12743117
12776125
14610273
14618243
14681479
15024413
15139022
15469906
15764147
15782199
15849611
15994289
16023393
16141072
16141073
16142913
16227996
16475818
16787915
16905747
16936804
17097837
17262811
17293870
17932044
18076961
18177727
18653481
18722041
18723004
18776082
18799693
19011085
19211831
19596281
19621945
19679638
20336479
20394798
20558581
20959604
21267068
21436314
22534978
22666436
23000401
23064962
23508576
24282296

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0070574  cadmium ion transmembrane transport
GO:0034599  cellular response to oxidative stress
GO:0006824  cobalt ion transport
GO:0006825  copper ion transport
GO:0048813  dendrite morphogenesis
GO:0048821  erythrocyte development
GO:0070627  ferrous iron import
GO:0015684  ferrous iron transport
GO:0006783  heme biosynthetic process
GO:0006811  ion transport
GO:0055072  iron ion homeostasis
GO:0034755  iron ion transmembrane transport
GO:0006826  iron ion transport
GO:0015692  lead ion transport
GO:0007611  learning or memory
GO:0071421  manganese ion transmembrane transport
GO:0006828  manganese ion transport
GO:0060586  multicellular organismal iron ion homeostasis
GO:0015675  nickel ion transport
GO:0006779  porphyrin biosynthetic process
GO:0006778  porphyrin metabolic process
GO:0015992  proton transport
GO:0010042  response to manganese ion
GO:0000041  transition metal ion transport
GO:0006810  transport
GO:0015676  vanadium ion transport

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0045178  basal part of cell
GO:0005903  brush border
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005769  early endosome
GO:0012505  endomembrane system
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005770  late endosome
GO:0031902  late endosome membrane
GO:0005765  lysosomal membrane
GO:0005764  lysosome
GO:0016020  membrane
GO:0005634  nucleus
GO:0070826  paraferritin complex
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0055037  recycling endosome
GO:0005802  trans-Golgi network
GO:0005773  vacuole

Molecular Function

GO:0046870  cadmium ion binding
GO:0015086  cadmium ion transmembrane transporter activity
GO:0050897  cobalt ion binding
GO:0015087  cobalt ion transmembrane transporter activity
GO:0005507  copper ion binding
GO:0005375  copper ion transmembrane transporter activity
GO:0015093  ferrous iron transmembrane transporter activity
GO:0015078  hydrogen ion transmembrane transporter activity
GO:0022890  inorganic cation transmembrane transporter activity
GO:0005506  iron ion binding
GO:0005381  iron ion transmembrane transporter activity
GO:0015094  lead ion transmembrane transporter activity
GO:0030145  manganese ion binding
GO:0005384  manganese ion transmembrane transporter activity
GO:0016151  nickel ion binding
GO:0015099  nickel ion transmembrane transporter activity
GO:0015295  solute:hydrogen symporter activity
GO:0005215  transporter activity
GO:0015100  vanadium ion transmembrane transporter activity
GO:0008270  zinc ion binding