neurotrophic tyrosine kinase, receptor, type 2

同義遺伝子名

GP145-TrkB/GP95-TrkB, BDNF/NT-3 growth factors receptor precursor, Trk-B, C030027L06Rik, Ntrk2, AI848316, Trkb, TrkB tyrosine kinase, neurotrophic tyrosine kinase, receptor, type 2, Neurotrophic tyrosine kinase receptor type 2, trkB, Tkrb

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:451.50

小脳:644.70

脳幹:444.90

脳梁:-

松果体:-

末梢神経:76.40

脊柱:283.70

網膜:225

目:45.60

動脈:337.60

静脈:-

リンパ節:-

末梢血:-

脾臓:13.20

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:71.30

GeneChip

大脳:10.37

小脳:9.69

脳幹:-

脳梁:-

松果体:-

末梢神経:9.27

脊柱:10.01

網膜:9.43

目:9.23

動脈:-

静脈:8.46

リンパ節:7.60

末梢血:-

脾臓:7.15

胸腺:-

骨髄:6.82

脂肪:10

骨:7.10

皮膚:8.14

CAGE

大脳:5.35

小脳:-

脳幹:5.56

脳梁:-

松果体:-

末梢神経:-

脊柱:5.37

網膜:-

目:-

動脈:4.80

静脈:-

リンパ節:1.98

末梢血:-

脾臓:0.41

胸腺:1.75

骨髄:-

脂肪:-

骨:1.97

皮膚:3.25

RNA-seq

大脳:52.37

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:41.40

前立腺:-

卵巣:23

精巣:-

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:9.10

肺:-

膀胱:66.20

腎臓:-

下垂体:51.70

甲状腺:112.50

副腎:-

膵臓:159.50

乳腺:71.80

唾液腺:-

GeneChip

子宮:9.05

胎盤:7.55

前立腺:7.69

卵巣:8.79

精巣:6.99

心臓:7.40

骨格筋:7.83

食道:-

胃:7.43

腸:7.47

結腸:-

肝臓:7.11

肺:7.67

膀胱:7.55

腎臓:7.29

下垂体:10.52

甲状腺:-

副腎:8.63

膵臓:8.36

乳腺:9.17

唾液腺:7.88

CAGE

子宮:3.30

胎盤:2.12

前立腺:2.43

卵巣:3.26

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:1.35

腸:0.58

結腸:0.57

肝臓:1.45

肺:2.03

膀胱:2.50

腎臓:-

下垂体:4.54

甲状腺:-

副腎:2.46

膵臓:2.56

乳腺:3.05

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.34

食道:-

胃:-

腸:-

結腸:-

肝臓:0

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008745
Gene ID	18212
Unigene ID	Mm.130054
Probe set ID	1420838_at [Mouse430_2]
Ensembl ID	ENSMUSG00000055254

オーソログ対応遺伝子

ヒト[14]	NM_001007097, NM_001018064, NM_001018065, NM_001018066, NM_006180
ラット[3]	NM_001163168, NM_001163169, NM_012731, NM_001018066, NM_006180

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020777	Tyrosine-protein kinase, neurotrophic receptor
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0031547	brain-derived neurotrophic factor receptor signaling pathway
GO:0030154	cell differentiation
GO:0021954	central nervous system neuron development
GO:0021987	cerebral cortex development
GO:0007631	feeding behavior
GO:0014047	glutamate secretion
GO:0007612	learning
GO:0007616	long-term memory
GO:0060291	long-term synaptic potentiation
GO:0042490	mechanoreceptor differentiation
GO:0007275	multicellular organismal development
GO:0043524	negative regulation of neuron apoptosis
GO:0007399	nervous system development
GO:0007528	neuromuscular junction development
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0048709	oligodendrocyte differentiation
GO:0048935	peripheral nervous system neuron development
GO:0016310	phosphorylation
GO:0050772	positive regulation of axonogenesis
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0043410	positive regulation of MAPKKK cascade
GO:0010976	positive regulation of neuron projection development
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0050773	regulation of dendrite development
GO:0043408	regulation of MAPKKK cascade
GO:0019222	regulation of metabolic process
GO:0046928	regulation of neurotransmitter secretion
GO:0051896	regulation of protein kinase B signaling cascade
GO:0032314	regulation of Rac GTPase activity
GO:0046548	retinal rod cell development
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001570	vasculogenesis

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005829	cytosol
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0005768	endosome
GO:0060076	excitatory synapse
GO:0030426	growth cone
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0043679	nerve terminal
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0048786	presynaptic active zone
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0048403	brain-derived neurotrophic factor binding
GO:0060175	brain-derived neurotrophic factor receptor activity
GO:0046875	ephrin receptor binding
GO:0016301	kinase activity
GO:0043121	neurotrophin binding
GO:0005030	neurotrophin receptor activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

neurotrophic tyrosine kinase, receptor, type 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function